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PureTech Health (Nasdaq: PRTC) announced that its founded entity, Akili Interactive (Nasdaq: AKLI), signed a definitive merger agreement with Virtual Therapeutics. The merger aims to create a leading digital health company focused on mental health solutions using immersive games. Akili shareholders will receive $0.4340 per share, representing a 4% premium to Akili's closing stock price on May 28, 2024, and an 85% premium to the closing price on April 29, 2024. The combined entity will operate as Virtual Therapeutics, with Akili as a wholly owned subsidiary. The merger is expected to close in Q3 2024, subject to certain conditions.
PureTech Health (Nasdaq: PRTC, LSE: PRTC), a clinical-stage biotherapeutics company, will present at the Jefferies Global Healthcare Conference on June 6, 2024. The event will feature a fireside chat with CEO Bharatt Chowrira and Co-founder Eric Elenko at 10:00am EDT / 3:00pm BST. A webcast of the presentation will be available on the PureTech Health investor website.
PureTech Health announced that Vedanta Biosciences has dosed the first patient in the global Phase 3 RESTORATiVE303 clinical study of VE303. This orally administered, live biotherapeutic candidate aims to prevent recurrent Clostridioides difficile infections (rCDI). The trial will evaluate VE303's efficacy and safety, laying the groundwork for a Biologics License Application to the FDA. Earlier Phase 2 results showed VE303 reduced CDI recurrence by 30.5%, indicating over an 80% reduction in recurrence odds. This pivotal study addresses a significant medical need, targeting a condition that affects up to 175,000 patients and causes around 20,000 deaths annually in the U.S.
PureTech Health (Nasdaq: PRTC, LSE: PRTC) has announced the launch of a $100 million tender offer to purchase up to 33,500,000 ordinary shares or ADSs at 250 pence per share, a 25% premium to its trailing volume-weighted average price. The offer, closing 20 June 2024 for ordinary shares and 18 June 2024 for ADSs, represents 12% of PureTech's issued share capital. Shareholder approval will be sought at a general meeting on 6 June 2024. Surplus funds from the tender offer may be returned as a special dividend. Investors are advised to consult tax professionals regarding federal income tax implications.
Seaport Therapeutics presented data from multiple clinical trials of SPT-300 at the Society of Biological Psychiatry Annual Meeting, showcasing significant progress in oral bioavailability and stress reduction for mood and anxiety disorders. The Phase 1 trial demonstrated nine times greater allopregnanolone exposure orally, while the Phase 2a trial showed a substantial reduction in stress-induced cortisol levels. These results validate the Glyph™ platform's ability to enhance bioavailability and support Seaport's ongoing studies in neuropsychiatry.
PureTech Health plc's Founded Entity, Seaport Therapeutics, has added industry expert Denice Torres, J.D., to its Board of Directors along with making key executive appointments. Michael Chen, Ph.D., is now the Chief Scientific Officer, and Eric Green, MBA, assumes the role of Chief Operating Officer. Seaport, specializing in neuropsychiatry, recently secured a $100 million Series A financing. PureTech retains a 61.5% equity stake in Seaport post-funding, aligning with its strategy to share later-stage development costs and focus on innovation.
