Company Description
Coeptis Therapeutics Holdings Inc. (Nasdaq: COEP), also referenced in company materials as COEPTIS, Inc., is described as a biopharmaceutical and technology company. Through its biopharmaceutical divisions and subsidiaries Coeptis Pharmaceuticals, Inc., GEAR Therapeutics, Inc., SNAP Biosciences, Inc., and Coeptis Technologies, Inc., the company focuses on developing cell therapy platforms and related technologies targeting cancer, autoimmune, and infectious diseases. According to multiple company announcements, Coeptis is headquartered in Wexford, Pennsylvania.
The biopharmaceutical operations are centered on cell-based immunotherapies and next-generation platforms. Company disclosures state that its therapeutic portfolio includes assets licensed from Deverra Therapeutics, such as an allogeneic cellular immunotherapy platform and DVX201, a clinical-stage, unmodified natural killer (NK) cell therapy technology. Coeptis is also working on a universal, multi-antigen CAR technology licensed from the University of Pittsburgh, known as SNAP-CAR, and GEAR cell therapy and companion diagnostic platforms developed in collaboration with VyGen-Bio and medical researchers at the Karolinska Institutet.
Cell therapy platforms and collaborations
Coeptis highlights several core platforms within its pipeline. The GEAR (Gene Edited Antibody Resistant) Cell Therapy Platform is described as a first-in-class approach to modifying immune cells to support combination strategies with monoclonal antibodies. Under an exclusive worldwide development and commercialization license from VyGen-Bio, the company formed GEAR Therapeutics, Inc. as a majority-owned subsidiary to advance GEAR-based cell therapy toward human proof-of-concept studies, initially focusing on GEAR-modified NK cells (GEAR-NK) for a broad range of cancers and other potential therapeutic modalities.
Company materials explain that GEAR-NK is being developed as a strategy to allow modified NK cells to be co-administered with targeted monoclonal antibodies that would otherwise affect NK cells due to shared receptors with malignant cells. The GEAR platform is also described as having potential applications in modifying hematopoietic stem cells in combination with monoclonal antibodies to improve bone marrow transplant outcomes in hematologic malignancies.
SNAP Biosciences, Inc., a majority-owned subsidiary and one of the biopharmaceutical divisions of Coeptis, is focused on the development of SNAP-CAR, which is described as a "universal" CAR (chimeric antigen receptor) cell therapy. According to company communications, SNAP-CAR uses a SNAP molecule to connect a CAR to tumor cells, enabling programmable antigen targeting through co-administered antibodies and providing flexibility to target multiple antigens and indications. A licensing agreement with Monarch Therapeutics Inc. gives SNAP Biosciences access to Monarch’s small-molecule adaptor-based technology platform to broaden the functionality of the Snap-Car NK cell therapy platform in oncology.
Technology division and AI-powered platforms
In addition to its biopharmaceutical activities, Coeptis has established a Technology Division that focuses on enhancing operational capabilities through advanced technologies. Company announcements describe this division as featuring AI-powered marketing software and robotic process automation tools acquired from NexGenAI Solutions Group. These tools are characterized as being designed to optimize business processes and improve efficiency.
Coeptis also owns the NexGenAI Affiliates Network, which is described as an AI-powered affiliate marketing platform that uses automation and advanced analytics to support marketing campaigns, including AI-driven content distribution, automated email outreach, and social media integration. The company has announced a co-working technology hub in India, operated by Ishvara Tech Consulting LLP, to support the NexGenAI Affiliates Group and initiatives in artificial intelligence, blockchain technologies, digital transformation, and robotic solutions for defense and security.
Hybrid business approach and revenue generation
External coverage cited by the company describes Coeptis as pursuing a dual-track or hybrid model that combines therapeutic development with complementary revenue streams from its technology platforms. In that context, the NexGenAI platform is identified as a contributor to revenue while the company advances its cell therapy research, including the GEAR Cell Therapy Platform and NK cell research. This approach is presented as a way to reduce reliance on dilutive funding while continuing to invest in biotechnology innovation.
Strategic transactions and planned corporate changes
Coeptis has announced a definitive merger agreement with Z Squared Inc., a Dogecoin-focused digital asset mining company. Under the agreement, a wholly owned subsidiary of Coeptis will merge with and into Z Squared, with Z Squared becoming a wholly owned subsidiary of Coeptis. Company communications state that in connection with this merger, Coeptis intends to spin out its biopharmaceutical operations and continue to operate those operations separately from Coeptis after the merger, while the technology operations are expected to remain in the company.
The company has filed a registration statement on Form S-4 with the U.S. Securities and Exchange Commission related to this proposed transaction, and a later announcement notes that the Form S-4 has been declared effective and that proxy materials are being mailed for an Annual/Special Meeting of stockholders to vote on the transaction. Coeptis also notes that the combined company has submitted an application to list the combined company’s common stock on The Nasdaq Stock Market LLC, while stating that approval has not yet been obtained and cannot be assured. Company disclosures indicate that if the combined company is unable to obtain listing on a national securities exchange, its securities would continue to trade on the OTC Markets following the transaction.
In the description of the merger, Coeptis states that it anticipates being rebranded and operating as Z Squared, Inc., and that the combined company will focus on advancing Z Squared’s digital asset mining expertise, primarily generating Dogecoin along with other digital assets such as Litecoin and other altcoins. The company also notes that the transaction is subject to customary closing conditions, including regulatory approvals, continued Nasdaq listing, and shareholder approvals.
Capital structure and partnerships
In a corporate update, Coeptis announced the extinguishment of a convertible note with YA II PN, Ltd (Yorkville), stating that this cleared the company’s outstanding debt obligations to that creditor. The company characterizes this as strengthening its capital structure and supporting its long-term goals, including a proposed strategic addition of operations in the cryptocurrency space.
Coeptis has also disclosed partnerships that connect its technology division with external companies. For example, NUBURU, Inc., a blue laser technology company, has described a strategic partnership with Coeptis’ NexGenAI Affiliates Network, characterizing NexGenAI as a provider of artificial intelligence and robotics solutions that use AI algorithms and data analytics to optimize marketing strategies, enhance customer engagement, and implement operational efficiencies.
Regulatory framework and compliance focus
In multiple company descriptions, Coeptis states that it operates within the regulatory framework set forth by the U.S. Food and Drug Administration (FDA) and emphasizes alignment with standards of compliance and patient care in its biopharmaceutical activities. This framing reflects the company’s positioning as a biotechnology developer working on cell therapy platforms that may require regulatory oversight for clinical development and potential future commercialization.
Business segments and thematic focus
Based on company materials, Coeptis can be viewed as operating across several thematic areas:
- Biopharmaceutical platforms: Development of cell therapy technologies, including allogeneic cellular immunotherapy, DVX201 NK cell therapy, GEAR-based immunotherapy, SNAP-CAR universal CAR technology, and associated companion diagnostics.
- Technology and AI: AI-powered marketing software, robotic process automation, and the NexGenAI Affiliates Network platform, with applications in marketing and operational efficiency.
- Digital assets and mining (planned): Through the proposed merger with Z Squared, a focus on Dogecoin and other digital asset mining, with an anticipated rebranding and strategic shift at the public-company level, while biopharmaceutical operations are intended to be spun out.
According to the company’s own descriptions, these activities are pursued through a combination of internal subsidiaries, licensed technologies, and collaborations with academic and industry partners.