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CRISPR Therapeutics AG (CRSP) Financials

CRSP
Trailing 12 months to June 30, 2026
Revenue $13.4M -64.8% YoY
Net Income -$451.1M +3.6% YoY
EPS (Diluted) -$4.74 +12.4% YoY
Free Cash Flow -$371.3M -14.1% YoY
Market Cap $4.8B as of Oct 17, 2026
Price / Sales 356x on $13.4M revenue, trailing 12 months to June 30, 2026
Price / Earnings n/m net loss, so no earnings multiple, trailing 12 months to June 30, 2026
Price / Book 2.7x on $1.7B equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 17, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 3, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the CRSP SEC filings page.

CRISPR Therapeutics AG (CRSP) reported $13.4M in revenue over the twelve months to Jun 30, 2026, down 64.8% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 12 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI CRSP FY2025

CRISPR Therapeutics operates as a research platform, with substantial development spending, recurring cash outflows, and little current revenue.

From FY2023 to FY2025, reported revenue fell from $371M to $3.5M while R&D remained $285M, showing that spending is driven by development activity rather than near-term sales volume. That combination makes reported revenue a poor gauge of the company's operating scale today.

In FY2025, the net loss was $582M while operating cash outflow was $345M; the gap indicates noncash charges or working-capital effects reduced the immediate cash impact of the accounting loss.

The balance sheet is lightly debt-funded: no long-term debt was reported, while liabilities were $343M. External financing supplied $426M in FY2025, and reported cash, equivalents, and investments equaled 68.7 months of the latest annual operating outflow.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 53 / 100
Financial Health Score 53/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of CRISPR Therapeutics AG's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
71

CRISPR Therapeutics AG held $2.0B in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $345.0M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and CRISPR Therapeutics AG scores 71/100 among other emerging companies.

Dilution
49

CRISPR Therapeutics AG had 96M shares outstanding at the end of fiscal year 2025, against 86M in fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and CRISPR Therapeutics AG scores 49/100 among other emerging companies.

R&D Intensity
73

CRISPR Therapeutics AG spent $284.8M on research and development in fiscal year 2025, which was 42.6% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and CRISPR Therapeutics AG scores 73/100 among other emerging companies.

Revenue Progress
1

CRISPR Therapeutics AG reported revenue of $3.5M in fiscal year 2025, against $37.3M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and CRISPR Therapeutics AG scores 1/100 among other emerging companies.

Burn Trend
33

CRISPR Therapeutics AG's operations used $345.0M of cash in fiscal year 2025, against $142.8M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and CRISPR Therapeutics AG scores 33/100 among other emerging companies.

Balance Sheet
90

CRISPR Therapeutics AG's cash, cash equivalents and investments came to $2.0B at the end of fiscal year 2025, against $343.4M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and CRISPR Therapeutics AG scores 90/100 among other emerging companies.

Altman Z-Score Safe
7.12

CRISPR Therapeutics AG scores 7.12, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($4.8B) relative to total liabilities ($343.4M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
1/7

CRISPR Therapeutics AG passes 1 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

CRISPR Therapeutics AG reported a net loss of $581.6M while operations used $345.0M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$10.2M
YoY+1041.4%
QoQ+598.3%

CRISPR Therapeutics AG generated $10.2M in revenue in Q2 2026. This represents an increase of 1041.4% from the same quarter a year earlier. Against the prior quarter it is up 598.3%.

EBITDA
-$113.0M
YoY+49.7%
QoQ+10.3%

CRISPR Therapeutics AG's EBITDA was -$113.0M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 49.7% from the same quarter a year earlier. Against the prior quarter it is up 10.3%.

Net Income
-$91.2M
YoY+56.3%
QoQ+25.8%

CRISPR Therapeutics AG reported -$91.2M in net income in Q2 2026. This represents an increase of 56.3% from the same quarter a year earlier. Against the prior quarter it is up 25.8%.

EPS (Diluted)
-$0.94
YoY+60.8%
QoQ+26.6%

CRISPR Therapeutics AG earned -$0.94 per diluted share (EPS) in Q2 2026. This represents an increase of 60.8% from the same quarter a year earlier. Against the prior quarter it is up 26.6%.

Cash & Balance Sheet

Free Cash Flow
-$84.1M
YoY+26.2%
QoQ+23.1%

CRISPR Therapeutics AG recorded an outflow of $84.1M in free cash flow in Q2 2026, representing a cash shortfall after capex. This represents an increase of 26.2% from the same quarter a year earlier. Against the prior quarter it is up 23.1%.

Cash & Debt
$291.3M
YoY+50.5%
QoQ-31.2%
5Y CAGR-29.3%
10Y CAGR+1.7%

CRISPR Therapeutics AG held $291.3M in cash against $586.2M in long-term debt as of Q2 2026.

Shares Outstanding
97M
YoY+6.3%
QoQ+0.3%
5Y CAGR+4.9%

CRISPR Therapeutics AG had 97M shares outstanding in Q2 2026. This represents an increase of 6.3% from the same quarter a year earlier. Against the prior quarter it is up 0.3%.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-5.2%
YoY+7.0pp
QoQ+1.5pp

CRISPR Therapeutics AG's ROE was -5.2% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 7.0 percentage points from the same quarter a year earlier. Against the prior quarter it is up 1.5 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$67.2M
YoY-3.9%
QoQ-2.1%

CRISPR Therapeutics AG invested $67.2M in research and development in Q2 2026. This represents a decrease of 3.9% from the same quarter a year earlier. Against the prior quarter it is down 2.1%.

Capital Expenditures
$648K
YoY+453.8%
QoQ+28.6%
5Y CAGR-53.1%
10Y CAGR-4.7%

CRISPR Therapeutics AG invested $648K in capex in Q2 2026, funding long-term assets and infrastructure. This represents an increase of 453.8% from the same quarter a year earlier. Against the prior quarter it is up 28.6%.

Share Buybacks

Not reported for Q2 2026.

CRSP Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CRSP quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Revenue$10.2M+1041.4%$1.5M+68.6%$864K-97.6%$889K+47.7%$892K+72.5%$865K+71.6%$35.7M$602K
R&D Expenses$67.2M-3.9%$68.6M-5.4%$83.5M+16.4%$58.9M-28.3%$69.9M-12.8%$72.5M-4.8%$71.7M$82.2M-9.4%
SG&A Expenses$17.6M-7.2%$17.2M-11.0%$18.4M+1.5%$16.9M-2.8%$18.9M-2.9%$19.3M+7.5%$18.1M$17.4M-4.8%
Operating Income-$117.3M+48.9%-$130.2M+12.2%-$154.8M-139.6%-$132.1M-19.9%-$229.3M-51.6%-$148.4M-5.6%-$64.6M-$110.1M+16.8%
EBITDA-$113.0M+49.7%-$125.9M+12.4%-$149.0M-149.4%-$127.7M-21.2%-$224.7M-53.4%-$143.7M-5.8%-$59.8M-$105.3M+17.4%
Interest Expense$3.3M$553KN/AN/A$0$0N/AN/A
Income Tax$960K-25.7%$839K-24.3%$614K-12.3%$619K-29.3%$1.3M+0.4%$1.1M+53.2%$700K$876K+112.6%
Net Income-$91.2M+56.3%-$122.9M+9.6%-$130.6M-250.1%-$106.4M-23.9%-$208.5M-65.0%-$136.0M-16.6%-$37.3M-$85.9M+23.4%
EPS (Basic)-$0.94+60.8%-$1.28+19.0%-$1.35-221.4%-$1.17-15.8%-$2.40-61.1%-$1.58-10.5%-$0.42-137.2%-$1.01+28.4%
EPS (Diluted)-$0.94+60.8%-$1.28+19.0%-$1.35-221.4%-$1.17-15.8%-$2.40-61.1%-$1.58-10.5%-$0.42-137.2%-$1.01+28.4%
Diluted Shares (Avg)97M+10.8%96M+11.8%N/A91M+7.1%87M+2.5%86M+5.1%N/A85M+7.3%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

CRSP Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CRSP quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$2.7B+30.6%$2.7B+25.8%$2.3B+1.0%$2.2B-0.5%$2.0B-13.3%$2.2B-11.2%$2.2B+0.6%$2.3B+8.1%
Current Assets$2.4B+36.8%$2.4B+31.1%$2.0B+2.5%$1.9B-0.8%$1.7B-13.8%$1.9B-11.9%$1.9B+1.5%$1.9B+10.4%
Cash & Equivalents$291.3M+50.5%$423.3M+80.0%$347.6M+16.5%$286.5M+27.0%$193.6M-60.0%$235.2M-66.8%$298.3M-23.4%$225.7M-57.2%
Short-Term Investments$2.1B+35.7%$2.0B+24.6%$1.6B+1.4%$1.6B-4.7%$1.5B+0.7%$1.6B+15.7%$1.6B+23.1%$1.7B+41.1%
Accounts ReceivableN/AN/A$0-100.0%$0$0$0$25.0M-87.5%$0
Long-Term Investments$0$0$0$28.4M$0-100.0%$0$0-100.0%$0
Total Liabilities$904.2M+183.8%$911.3M+170.5%$343.4M+10.8%$329.3M+4.1%$318.6M-11.2%$336.9M-5.1%$310.0M-10.6%$316.5M-11.9%
Current Liabilities$132.9M+27.3%$136.3M+14.1%$149.1M+69.9%$119.0M+32.5%$104.4M-18.4%$119.4M+0.4%$87.8M-19.3%$89.8M-19.3%
Non-Current Liabilities$771.3M+260.1%$775.0M+256.3%$194.3M-12.5%$210.4M-7.2%$214.2M-7.3%$217.5M-7.9%$222.2M-6.6%$226.7M-8.5%
Long-Term Debt$586.2M$585.5M$0N/AN/AN/AN/AN/A
Total Equity$1.7B+2.1%$1.8B-0.8%$1.9B-0.5%$1.9B-1.2%$1.7B-13.6%$1.8B-12.2%$1.9B+2.6%$1.9B+12.3%
Retained Earnings-$2.2B-26.4%-$2.1B-37.9%-$1.9B-42.6%-$1.8B-36.8%-$1.7B-37.6%-$1.5B-34.5%-$1.4B-36.6%-$1.3B-22.0%

Not reported in any period shown, so not listed: Inventory, Goodwill.

CRSP Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CRSP quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$83.5M+26.7%-$108.9M-101.9%-$92.6M-85.0%-$84.6M+20.8%-$113.9M-19.1%-$53.9M-149.2%-$50.0M+47.9%-$106.9M-168.2%
Depreciation & Amortization$4.3M-6.5%$4.3M-8.8%$5.7M+16.9%$4.4M-8.3%$4.6M-4.2%$4.7M-2.0%$4.8M-1.2%$4.8M-2.0%
Stock-Based Compensation$17.3M-1.7%$16.3M-19.2%N/A$16.6M-22.9%$17.6M-25.6%$20.2M+4.2%N/A$21.5M+7.9%
Capital Expenditures$648K+453.8%$504K+144.7%$517K+103.5%$74K-66.2%$117K-83.5%$206K-71.4%$254K-65.6%$219K-89.7%
Free Cash Flow-$84.1M+26.2%-$109.4M-102.0%-$93.1M-85.1%-$84.7M+20.9%-$114.0M-18.4%-$54.2M-149.7%-$50.3M+48.1%-$107.1M-155.2%
Investing Cash Flow-$55.7M-179.5%-$410.7M-1979.2%$37.2M-64.8%-$119.2M+26.2%$70.0M+155.1%-$19.8M+79.8%$105.8M+229.9%-$161.6M-233.2%
Financing Cash Flow$7.2M+218.0%$591.9M+5490.4%$116.4M+589.8%$296.8M+2978.5%$2.3M+584.5%$10.6M-96.5%$16.9M-56.7%$9.6M+519.5%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

CRSP Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CRSP quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Margin-1151.8%-8933.3%-17912.5%-14854.8%-25709.0%-17158.8%-181.0%-18294.0%
Net Margin-895.3%-8431.5%-15117.3%-11973.1%-23379.9%-15722.1%-104.5%-14276.1%
Return on Equity-5.2%+7.0pp-6.8%+0.7pp-6.8%-4.9pp-5.6%-1.1pp-12.2%-5.8pp-7.4%-1.8pp-1.9%-4.4%+2.1pp
Return on Assets-3.4%+6.8pp-4.5%+1.8pp-5.8%-4.1pp-4.7%-0.9pp-10.3%-4.9pp-6.3%-1.5pp-1.7%-3.8%+1.6pp
Current Ratio17.85+1.2x17.96+2.3x13.32-8.8x16.22-5.4x16.61+0.9x15.64-2.2x22.07+4.5x21.64+5.8x
Debt-to-Equity0.34+0.1x0.32+0.1x0.00-0.2x0.170.0x0.190.0x0.180.0x0.160.0x0.160.0x
Asset Turnover0.000.0x0.000.0x0.000.0x0.000.0x0.000.0x0.000.0x0.020.000.0x
FCF Margin-826.5%-7503.5%-10772.0%-9528.5%-12779.9%-6260.5%-140.9%-17796.0%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
CRISPR Therapeutics AG CRSP FY2025 $3.5M -$581.6M N/A $4.8B 53/100
Merus N.V. MRUS FY2024 $36.1M -$215.3M N/A $6.8B 59/100
TG Therapeutics, Inc. TGTX FY2025 $616.3M $447.2M 72.6% $8.3B 60/100
PTC Therapeutics, Inc. PTCT FY2025 $1.7B $683.0M 39.5% $4.9B 53/100
Legend Biotech Corporation LEGN FY2025 $1.0B -$296.8M -28.8% $3.6B 41/100

Frequently Asked Questions

What is CRISPR Therapeutics AG's annual revenue?

CRISPR Therapeutics AG (CRSP) reported $3.5M in total revenue for fiscal year 2025. This represents a -90.6% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is CRISPR Therapeutics AG's revenue growing?

CRISPR Therapeutics AG (CRSP) revenue declined by 90.6% year-over-year, from $37.3M to $3.5M in fiscal year 2025.

Is CRISPR Therapeutics AG profitable?

No, CRISPR Therapeutics AG (CRSP) reported a net income of -$581.6M in fiscal year 2025.

CRISPR Therapeutics AG (CRSP) reported diluted earnings per share of -$6.47 for fiscal year 2025. This represents a -49.1% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

CRISPR Therapeutics AG (CRSP) had EBITDA of -$645.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, CRISPR Therapeutics AG (CRSP) had $347.6M in cash and equivalents against $0 in long-term debt.

CRISPR Therapeutics AG (CRSP) has a return on equity of -30.3% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

CRISPR Therapeutics AG (CRSP) recorded an outflow of $345.9M in free cash flow during fiscal year 2025. This represents a -139.1% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

CRISPR Therapeutics AG (CRSP) recorded an outflow of $345.0M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

CRISPR Therapeutics AG (CRSP) had $2.3B in total assets as of fiscal year 2025, including both current and long-term assets.

CRISPR Therapeutics AG (CRSP) invested $914K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

CRISPR Therapeutics AG (CRSP) invested $284.8M in research and development during fiscal year 2025.

CRISPR Therapeutics AG (CRSP) had 96M shares outstanding as of fiscal year 2025.

CRISPR Therapeutics AG (CRSP) had a current ratio of 13.32 as of fiscal year 2025, which is generally considered healthy.

CRISPR Therapeutics AG (CRSP) had a debt-to-equity ratio of 0.00 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

CRISPR Therapeutics AG (CRSP) had a return on assets of -25.7% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

CRISPR Therapeutics AG (CRSP) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (trailing 12 months to June 30, 2026). The market capitalization is $4.8B as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

CRISPR Therapeutics AG (CRSP) trades at 356x sales, its market capitalization divided by revenue of $13.4M revenue, trailing 12 months to June 30, 2026. The market capitalization is $4.8B as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, CRISPR Therapeutics AG (CRSP) held $2.0B in cash, cash equivalents and investments, and reported an operating cash outflow of $345.0M over that year. Dividing the one by the other, the reported balance equals about 69 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

CRISPR Therapeutics AG (CRSP) has an Altman Z-Score of 7.12, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

CRISPR Therapeutics AG (CRSP) has a Piotroski F-Score of 1 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

CRISPR Therapeutics AG (CRSP) reported a net loss of $581.6M while operations used $345.0M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

CRISPR Therapeutics AG (CRSP) scores 53 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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