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Design Therapeutics, Inc. Financials

DSGN
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Design Therapeutics, Inc. (DSGN) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Piotroski F-Score Weak
1/9

Design Therapeutics, Inc. passes 1 of 9 financial strength tests. 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality Low Quality
0.78x

For every $1 of reported earnings, Design Therapeutics, Inc. generates $0.78 in operating cash flow (-$54.4M OCF vs -$69.8M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Earnings & Revenue

Revenue
$0

Design Therapeutics, Inc. generated $0 in revenue in fiscal year 2025.

EBITDA
-$78.8M
YoY-27.6%

Design Therapeutics, Inc.'s EBITDA was -$78.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 27.6% from the prior year.

Net Income
-$69.8M
YoY-40.7%

Design Therapeutics, Inc. reported -$69.8M in net income in fiscal year 2025. This represents a decrease of 40.7% from the prior year.

EPS (Diluted)
$-1.22
YoY-38.6%

Design Therapeutics, Inc. earned $-1.22 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 38.6% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$54.6M
YoY-25.6%

Design Therapeutics, Inc. generated -$54.6M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 25.6% from the prior year.

Cash & Debt
$16.9M
YoY-25.3%
5Y CAGR+47.9%

Design Therapeutics, Inc. held $16.9M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
60M
YoY+6.4%

Design Therapeutics, Inc. had 60M shares outstanding in fiscal year 2025. This represents an increase of 6.4% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
N/A
Net Margin
N/A
Return on Equity
-32.8%
YoY-12.4pp

Design Therapeutics, Inc.'s ROE was -32.8% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 12.4 percentage points from the prior year.

Capital Allocation

R&D Spending
$59.1M
YoY+33.3%
5Y CAGR+57.7%

Design Therapeutics, Inc. invested $59.1M in research and development in fiscal year 2025. This represents an increase of 33.3% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$193K
YoY-43.2%
5Y CAGR+20.5%

Design Therapeutics, Inc. invested $193K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 43.2% from the prior year.

DSGN Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue N/A N/A N/A $0 N/A N/A N/A N/A
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses N/A $14.6M-7.3% $15.7M+2.3% $15.4M N/A $11.9M+12.9% $10.5M+7.3% $9.8M
SG&A Expenses N/A $4.7M-19.0% $5.8M+15.7% $5.0M N/A $4.4M-3.5% $4.5M-1.6% $4.6M
Operating Income N/A -$19.3M+10.5% -$21.6M-5.6% -$20.4M N/A -$16.2M-8.0% -$15.0M-4.5% -$14.4M
Interest Expense N/A N/A N/A N/A N/A N/A N/A N/A
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income N/A -$17.0M+10.9% -$19.1M-7.7% -$17.7M N/A -$13.0M-10.6% -$11.8M-6.2% -$11.1M
EPS (Diluted) N/A $-0.30+11.8% $-0.34-9.7% $-0.31 N/A $-0.23-9.5% $-0.21-5.0% $-0.20

DSGN Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $226.2M+6.8% $211.8M-5.0% $222.9M-6.1% $237.5M-5.8% $252.1M-3.6% $261.6M-3.0% $269.6M-3.3% $278.8M
Current Assets $223.8M+7.1% $209.0M-4.9% $219.8M-5.9% $233.6M-5.8% $248.0M-3.6% $257.2M-2.9% $264.8M-3.3% $273.9M
Cash & Equivalents $16.9M+11.7% $15.1M-23.4% $19.7M+44.2% $13.7M-39.4% $22.6M-25.6% $30.3M-33.6% $45.7M+55.5% $29.4M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $13.7M+13.7% $12.1M+22.3% $9.8M+3.1% $9.6M-4.4% $10.0M+8.9% $9.2M+10.0% $8.3M-9.7% $9.2M
Current Liabilities $13.1M+16.8% $11.2M+27.7% $8.7M+6.2% $8.2M-2.7% $8.5M+13.9% $7.4M+16.2% $6.4M-9.9% $7.1M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $212.5M+6.4% $199.7M-6.3% $213.0M-6.5% $227.9M-5.9% $242.1M-4.1% $252.5M-3.4% $261.2M-3.1% $269.6M
Retained Earnings -$297.0M-5.7% -$281.0M-6.4% -$264.0M-7.8% -$244.9M-7.8% -$227.2M-6.4% -$213.6M-6.5% -$200.5M-6.2% -$188.7M

DSGN Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$12.0M-7.2% -$11.2M+22.7% -$14.4M+14.0% -$16.8M-70.3% -$9.9M-3.3% -$9.5M+15.2% -$11.3M+9.5% -$12.4M
Capital Expenditures $34K $0-100.0% $87K+20.8% $72K $0+100.0% -$16K-109.9% $161K-17.4% $195K
Free Cash Flow -$12.0M-7.5% -$11.2M+23.2% -$14.5M+13.8% -$16.9M-71.0% -$9.9M-3.1% -$9.6M+16.3% -$11.4M+9.6% -$12.6M
Investing Cash Flow -$11.6M-277.9% $6.5M-67.6% $20.1M+155.6% $7.9M+329.6% $1.8M+131.4% -$5.8M-121.3% $27.3M+32.6% $20.6M
Financing Cash Flow $25.3M+68324.3% $37K-89.8% $361K+1469.6% $23K-91.3% $263K+26200.0% $1K-99.6% $229K+1045.0% $20K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

DSGN Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A N/A N/A N/A N/A N/A N/A N/A
Net Margin N/A N/A N/A N/A N/A N/A N/A N/A
Return on Equity N/A -8.5%+0.5pp -9.0%-1.2pp -7.8% N/A -5.2%-0.6pp -4.5%-0.4pp -4.1%
Return on Assets N/A -8.0%+0.5pp -8.6%-1.1pp -7.5% N/A -5.0%-0.6pp -4.4%-0.4pp -4.0%
Current Ratio 17.14-1.6 18.71-6.4 25.13-3.2 28.37-0.9 29.31-5.3 34.61-6.8 41.42+2.8 38.61
Debt-to-Equity 0.060.0 0.06+0.0 0.050.0 0.040.0 0.040.0 0.040.0 0.030.0 0.03
FCF Margin N/A N/A N/A N/A N/A N/A N/A N/A

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Frequently Asked Questions

Design Therapeutics, Inc. (DSGN) reported $0 in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

No, Design Therapeutics, Inc. (DSGN) reported a net income of -$69.8M in fiscal year 2025.

Design Therapeutics, Inc. (DSGN) reported diluted earnings per share of $-1.22 for fiscal year 2025. This represents a -38.6% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Design Therapeutics, Inc. (DSGN) had EBITDA of -$78.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Design Therapeutics, Inc. (DSGN) has a return on equity of -32.8% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Design Therapeutics, Inc. (DSGN) generated -$54.6M in free cash flow during fiscal year 2025. This represents a -25.6% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Design Therapeutics, Inc. (DSGN) generated -$54.4M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Design Therapeutics, Inc. (DSGN) had $226.2M in total assets as of fiscal year 2025, including both current and long-term assets.

Design Therapeutics, Inc. (DSGN) invested $193K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Design Therapeutics, Inc. (DSGN) invested $59.1M in research and development during fiscal year 2025.

Design Therapeutics, Inc. (DSGN) had 60M shares outstanding as of fiscal year 2025.

Design Therapeutics, Inc. (DSGN) had a current ratio of 17.14 as of fiscal year 2025, which is generally considered healthy.

Design Therapeutics, Inc. (DSGN) had a debt-to-equity ratio of 0.06 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Design Therapeutics, Inc. (DSGN) had a return on assets of -30.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Design Therapeutics, Inc. (DSGN) had $16.9M in cash against an annual operating cash burn of $54.4M. This gives an estimated cash runway of approximately 4 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Design Therapeutics, Inc. (DSGN) has a Piotroski F-Score of 1 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Design Therapeutics, Inc. (DSGN) has an earnings quality ratio of 0.78x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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