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Monte Rosa Therapeutics, Inc. Financials

GLUE
FY2025 annual
Revenue $123.7M +63.5% YoY
Net Income -$38.6M +46.9% YoY
EPS (Diluted) -$0.46 +53.1% YoY
Free Cash Flow -$27.5M -172.3% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Monte Rosa Therapeutics, Inc. (GLUE) reported $123.7M in revenue for fiscal year 2025, up 63.5% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI GLUE FY2025

Monte Rosa’s shrinking operating loss reflects better revenue absorption, but cash conversion moved backward as research intensity stayed high.

In the latest year, earnings quality weakened as operating cash flow swung from $42.0M positive to -$22.8M negative. That happened even as the net loss improved to -$38.6M, so reported progress relied more on accounting than on cash creation and forced the balance sheet, not the business itself, to finance a larger share of activity.

Revenue scale is starting to absorb overhead: sales reached $123.7M while operating margin improved to -43.8%, showing that incremental revenue is now covering a larger share of fixed costs. But R&D still sits above revenue at $141.5M, and SG&A barely moved, so the narrower loss reflects better fixed-cost absorption rather than a retreat from discovery spending.

Liquidity improved for a less obvious reason: the current ratio rose to 6.1x even though cash fell to $129.9M, meaning near-term obligations eased faster than liquid resources did. Funding remains partly external: shares outstanding reached 65.5M while financing cash provided $30.4M, a sign that runway support still came from fresh capital rather than internally generated cash.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity CashFlow Returns 57 / 100
Financial Health Score 57/100

Scored against operating companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Monte Rosa Therapeutics, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
24

Monte Rosa Therapeutics, Inc. has an operating margin of -43.8%, meaning the company loses $44 on every $100 of revenue. This results in a profitability score of 24/100. This is up from -107.3% the prior year.

Growth
96

Monte Rosa Therapeutics, Inc.'s revenue surged 63.5% year-over-year to $123.7M, reflecting rapid business expansion. This strong growth earns a score of 96/100.

Leverage
48

Monte Rosa Therapeutics, Inc. has a moderate D/E ratio of 0.93. This balance of debt and equity financing earns a leverage score of 48/100.

Liquidity
93

With a current ratio of 6.12, Monte Rosa Therapeutics, Inc. holds $6.12 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 93/100.

Cash Flow
47

Monte Rosa Therapeutics, Inc.'s operations used $22.8M of cash, and capex of $4.7M added to the outflow, for a free cash flow shortfall of $27.5M. This results in a cash flow score of 47/100.

Returns
31

Monte Rosa Therapeutics, Inc. posts a -16.6% return on equity (ROE), meaning it loses $17 for every $100 of shareholders' equity. This results in a returns score of 31/100. This is up from -32.6% the prior year.

Altman Z-Score Grey Zone
2.54

Monte Rosa Therapeutics, Inc. scores 2.54, placing it in the grey zone between 1.81 and 2.99. The score is driven primarily by a large market capitalization ($1.2B) relative to total liabilities ($215.6M). This signals moderate financial risk that warrants monitoring.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/7

Monte Rosa Therapeutics, Inc. passes 4 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Monte Rosa Therapeutics, Inc. reported a net loss of $38.6M while operations used $22.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$123.7M
YoY+63.5%

Monte Rosa Therapeutics, Inc. generated $123.7M in revenue in fiscal year 2025. This represents an increase of 63.5% from the prior year.

EBITDA
-$43.4M
YoY+38.8%

Monte Rosa Therapeutics, Inc.'s EBITDA was -$43.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 38.8% from the prior year.

Net Income
-$38.6M
YoY+46.9%

Monte Rosa Therapeutics, Inc. reported -$38.6M in net income in fiscal year 2025. This represents an increase of 46.9% from the prior year.

EPS (Diluted)
-$0.46
YoY+53.1%

Monte Rosa Therapeutics, Inc. earned -$0.46 per diluted share (EPS) in fiscal year 2025. This represents an increase of 53.1% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$27.5M
YoY-172.3%

Monte Rosa Therapeutics, Inc. recorded an outflow of $27.5M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 172.3% from the prior year.

Cash & Debt
$129.9M
YoY-42.1%
5Y CAGR+25.5%

Monte Rosa Therapeutics, Inc. held $129.9M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
66M
YoY+6.6%

Monte Rosa Therapeutics, Inc. had 66M shares outstanding in fiscal year 2025. This represents an increase of 6.6% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Operating Margin
-43.8%

Monte Rosa Therapeutics, Inc.'s operating margin was -43.8% in fiscal year 2025, reflecting core business profitability. No change is given against fiscal year 2024: its reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin
-31.2%
YoY+64.9pp

Monte Rosa Therapeutics, Inc.'s net profit margin was -31.2% in fiscal year 2025, showing the share of revenue converted to profit. This is up 64.9 percentage points from the prior year.

Return on Equity
-16.6%
YoY+16.1pp

Monte Rosa Therapeutics, Inc.'s ROE was -16.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 16.1 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$141.5M
YoY+16.4%
5Y CAGR+42.6%

Monte Rosa Therapeutics, Inc. invested $141.5M in research and development in fiscal year 2025. This represents an increase of 16.4% from the prior year.

Capital Expenditures
$4.7M
YoY+17.9%
5Y CAGR+6.8%

Monte Rosa Therapeutics, Inc. invested $4.7M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 17.9% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

GLUE Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

GLUE annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20
Revenue$28.7M$123.7M+63.5%$75.6M$0N/AN/AN/A
R&D Expenses$170.7M$141.5M+16.4%$121.6M+9.2%$111.3M+30.8%$85.1M+48.8%$57.2M+138.1%$24.0M
SG&A Expenses$39.9M$36.4M+3.4%$35.2M+9.8%$32.0M+17.3%$27.3M+73.7%$15.7M+292.7%$4.0M
Operating Income-$181.9M-$54.2M+33.2%-$81.1M+43.4%-$143.3M-27.5%-$112.4M-54.2%-$72.9M-160.2%-$28.0M
Income Tax-$2.9M-$1.1M-142.7%$2.6M+660.4%$338K$0N/AN/A
Net Income-$161.1M-$38.6M+46.9%-$72.7M+46.3%-$135.4M-24.7%-$108.5M-46.7%-$74.0M-106.1%-$35.9M
EPS (Diluted)-$0.46+53.1%-$0.98+62.7%-$2.63-14.3%-$2.30-$2.96N/A

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

GLUE Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

GLUE annual balance sheet
MetricFY25FY24FY23FY22FY21FY20
Total Assets$448.7M+2.3%$438.7M+44.4%$303.8M-11.3%$342.4M-6.5%$366.3M+641.9%$49.4M
Current Assets$393.2M+4.2%$377.4M+59.8%$236.2M-14.4%$275.9M-20.9%$348.7M+699.9%$43.6M
Cash & Equivalents$129.9M-42.1%$224.3M+75.1%$128.1M+133.3%$54.9M-84.1%$346.1M+729.9%$41.7M
Total Liabilities$215.6M-0.1%$215.8M+73.3%$124.5M+75.4%$71.0M+277.3%$18.8M-80.8%$98.1M
Current Liabilities$64.2M-59.1%$156.9M+236.9%$46.6M+82.2%$25.6M+53.7%$16.6M-43.2%$29.3M
Total Equity$233.1M+4.5%$222.9M+24.4%$179.3M-34.0%$271.4M-21.9%$347.5M+813.2%-$48.7M
Retained Earnings-$477.2M-8.8%-$438.6M-19.9%-$365.9M-58.7%-$230.5M-88.9%-$122.0M-153.8%-$48.1M

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

GLUE Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

GLUE annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20
Operating Cash Flow-$24.1M-$22.8M-154.3%$42.0M+195.9%-$43.8M+52.6%-$92.5M-55.8%-$59.4M-157.5%-$23.1M
Capital Expenditures$8.0M$4.7M+17.9%$4.0M-79.1%$19.0M+47.5%$12.9M+32.7%$9.7M+187.2%$3.4M
Free Cash Flow-$32.1M-$27.5M-172.3%$38.0M+160.5%-$62.8M+40.4%-$105.4M-52.5%-$69.1M-161.3%-$26.4M
Investing Cash Flow-$316.8M-$101.8M-129.1%-$44.5M-150.1%$88.8M+140.5%-$219.2M-2171.0%-$9.7M-184.8%-$3.4M
Financing Cash Flow$361.5M$30.4M-69.3%$98.9M+259.7%$27.5M+34.3%$20.5M-94.6%$377.6M+528.6%$60.1M
Dividends Paid$0$0$0$0$0$0N/A

Not reported in any period shown, so not listed: Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

GLUE Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

GLUE annual financial ratios
MetricFY25FY24FY23FY22FY21FY20
Operating Margin-43.8%-107.3%N/AN/AN/AN/A
Net Margin-31.2%+64.9pp-96.1%N/AN/AN/AN/A
Return on Equity-16.6%+16.1pp-32.6%+42.9pp-75.5%-35.5pp-40.0%-18.7pp-21.3%N/A
Return on Assets-8.6%+8.0pp-16.6%+28.0pp-44.6%-12.9pp-31.7%-11.5pp-20.2%+52.5pp-72.7%
Current Ratio6.12+3.7x2.40-2.7x5.07-5.7x10.79-10.2x20.96+19.5x1.49
Debt-to-Equity0.930.0x0.97+0.3x0.69+0.4x0.26+0.2x0.05N/A
FCF Margin-22.2%-72.5pp50.3%N/AN/AN/AN/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin.

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Frequently Asked Questions

What is Monte Rosa Therapeutics, Inc.'s annual revenue?

Monte Rosa Therapeutics, Inc. (GLUE) reported $123.7M in total revenue for fiscal year 2025. This represents a 63.5% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Monte Rosa Therapeutics, Inc.'s revenue growing?

Monte Rosa Therapeutics, Inc. (GLUE) revenue grew by 63.5% year-over-year, from $75.6M to $123.7M in fiscal year 2025.

Is Monte Rosa Therapeutics, Inc. profitable?

No, Monte Rosa Therapeutics, Inc. (GLUE) reported a net income of -$38.6M in fiscal year 2025, with a net profit margin of -31.2%.

Monte Rosa Therapeutics, Inc. (GLUE) reported diluted earnings per share of -$0.46 for fiscal year 2025. This represents a 53.1% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Monte Rosa Therapeutics, Inc. (GLUE) had EBITDA of -$43.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Monte Rosa Therapeutics, Inc. (GLUE) had an operating margin of -43.8% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Monte Rosa Therapeutics, Inc. (GLUE) had a net profit margin of -31.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Monte Rosa Therapeutics, Inc. (GLUE) has a return on equity of -16.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Monte Rosa Therapeutics, Inc. (GLUE) recorded an outflow of $27.5M in free cash flow during fiscal year 2025. This represents a -172.3% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Monte Rosa Therapeutics, Inc. (GLUE) recorded an outflow of $22.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Monte Rosa Therapeutics, Inc. (GLUE) had $448.7M in total assets as of fiscal year 2025, including both current and long-term assets.

Monte Rosa Therapeutics, Inc. (GLUE) invested $4.7M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Monte Rosa Therapeutics, Inc. (GLUE) invested $141.5M in research and development during fiscal year 2025.

Monte Rosa Therapeutics, Inc. (GLUE) had 66M shares outstanding as of fiscal year 2025.

Monte Rosa Therapeutics, Inc. (GLUE) had a current ratio of 6.12 as of fiscal year 2025, which is generally considered healthy.

Monte Rosa Therapeutics, Inc. (GLUE) had a debt-to-equity ratio of 0.93 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Monte Rosa Therapeutics, Inc. (GLUE) had a return on assets of -8.6% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Monte Rosa Therapeutics, Inc. (GLUE) had $129.9M in cash against an annual operating cash burn of $22.8M. This gives an estimated cash runway of approximately 68 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Monte Rosa Therapeutics, Inc. (GLUE) has an Altman Z-Score of 2.54, placing it in the Grey Zone (moderate risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Monte Rosa Therapeutics, Inc. (GLUE) has a Piotroski F-Score of 4 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Monte Rosa Therapeutics, Inc. (GLUE) reported a net loss of $38.6M while operations used $22.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Monte Rosa Therapeutics, Inc. (GLUE) scores 57 out of 100 on our Financial Health Score, indicating moderate standing within its operating companies peer group. The score is a 0-100 composite of six dimensions (Profitability, Growth, Leverage, Liquidity, Cash Flow, Returns), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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