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Agilent BioTek Cytation C10 Confocal Imaging Reader Enhanced with Innovative Water Immersion Technology

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Agilent Technologies Inc. (NYSE: A) introduces water immersion and new confocal spinning disk technology to the BioTek Cytation C10 confocal imaging reader. These features enhance image quality for live-cell and 3D applications, reducing deleterious effects on live-cell samples and improving clarity for thicker samples such as tissues and 3-D spheroids.
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Empowering researchers with superior imaging performance for cutting-edge live-cell and three-dimensional applications

SANTA CLARA, Calif.--(BUSINESS WIRE)-- Agilent Technologies Inc. (NYSE: A) today announced the addition of water immersion and new confocal spinning disk technology to the BioTek Cytation C10 confocal imaging reader. These features improve image quality and results by reducing deleterious effects on live-cell samples and enhancing clarity for thicker samples such as tissues and 3-D spheroids.

In light microscopy, water immersion technology automatically and consistently places a layer of water between the objective lens and the sample. The higher refractive index of water, as compared to air, effectively increases the numerical aperture of the objective lens; this reduces z-axis distortion, resulting in higher image quality and a more true-to-life representation of thick and three-dimensional cell models. Water immersion also benefits researchers who are increasingly turning to physiologically relevant live-cell (as opposed to fixed-cell) applications by reducing exposure times, thus lowering the phototoxic effects traditionally associated with these experiments.

Spinning disk confocal technology improves microscopic images by blocking out-of-focus light from reaching the image sensor. The new deep-sectioning spinning disk (DSD), now available as an option on the Cytation C10, allows researchers to look deeper into thick samples with less out-of-focus blur. The clearer images that result are particularly beneficial in quantitative analysis applications.

“The additions of water immersion objectives and a deep-sectioning confocal spinning disk to the Cytation C10 add significant new capabilities for researchers requiring the best imaging performance for live-cell and 3D applications,” stated Caleb Foster, associate vice president of marketing in Agilent’s Cell Analysis Division. “As the demands continue to grow for more complex physiologically relevant live-cell models, the Cytation C10 will be an invaluable and transformative research tool to support these imaging application areas.”

Designed as an affordable, high-performance confocal microscopy system, the Cytation C10 employs high-quality components, including a Hamamatsu scientific CMOS (sCMOS) camera, Olympus objectives, and laser-based illumination. Onboard environmental controls, widefield fluorescence, brightfield, and phase contrast optics further enhance the system’s capabilities. Additionally, integrating it with the Agilent BioTek BioSpa 8 automated incubator enables efficient multi-plate live-cell analysis.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in analytical and clinical laboratory technologies, delivering insights and innovation that help our customers bring great science to life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.85 billion in fiscal 2022 and employs 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, please subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.

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Naomi Goumillout

Agilent Technologies

+1.978.314.1862

naomi.goumillout@agilent.com

Source: Agilent Technologies Inc.

FAQ

What are the new features added to the BioTek Cytation C10 confocal imaging reader by Agilent Technologies Inc. (NYSE: A)?

Agilent Technologies Inc. (NYSE: A) has added water immersion and new confocal spinning disk technology to the BioTek Cytation C10 confocal imaging reader.

How do the water immersion and confocal spinning disk technology improve image quality for live-cell and 3D applications?

The water immersion technology reduces z-axis distortion and enhances clarity for thicker samples, while the spinning disk technology blocks out-of-focus light, resulting in clearer images.

What are the benefits of water immersion technology for researchers working with live-cell applications?

Water immersion technology reduces exposure times and lowers phototoxic effects traditionally associated with live-cell experiments.

What components does the Cytation C10 employ to ensure high-quality imaging performance?

The Cytation C10 uses high-quality components, including a Hamamatsu scientific CMOS (sCMOS) camera, Olympus objectives, and laser-based illumination.

How can the Cytation C10 be integrated for efficient multi-plate live-cell analysis?

Integrating the Cytation C10 with the Agilent BioTek BioSpa 8 automated incubator enables efficient multi-plate live-cell analysis.

Agilent Technologies Inc.

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