Abbvie Inc Stock Price, News & Analysis

AbbVie (NYSE: ABBV) and Gubra A/S have announced a license agreement to develop GUB014295, a potential best-in-class, long-acting amylin analog for obesity treatment. This partnership marks AbbVie's strategic entry into the obesity market.

The agreement includes a $350 million upfront payment to Gubra, with potential additional payments of up to $1.875 billion in development, commercial, and sales milestones, plus tiered royalties on global net sales. AbbVie will lead global development and commercialization activities.

GUB014295, currently in Phase 1 clinical trials, is an agonist that activates amylin and calcitonin receptors. The compound works by triggering appetite suppression signals to the brain, reducing food intake, and delaying gastric emptying. This development addresses a significant global health concern, with approximately 900 million adults affected by obesity.

AbbVie (NYSE: ABBV) received a positive CHMP opinion recommending approval of upadacitinib (RINVOQ®) for treating adult patients with Giant Cell Arteritis (GCA). The recommendation is based on the Phase 3 SELECT-GCA trial results, which demonstrated efficacy in achieving sustained remission and other key endpoints.

If approved by the European Commission in the first half of 2025, RINVOQ would become the first and only oral advanced therapy for adults with GCA. The trial evaluated upadacitinib (15 mg, once daily) in adults aged 50 and older, comparing 7.5 mg or 15 mg doses combined with a 26-week corticosteroid taper regimen against placebo with a 52-week taper.

The safety profile during the 52-week, placebo-controlled period aligned with observations from other approved indications. RINVOQ is currently approved in the EU for multiple conditions including radiographic axial spondylarthritis, psoriatic arthritis, and Crohn's disease, though not yet for GCA.

AbbVie (NYSE: ABBV) has announced its upcoming participation in TD Cowen's 45th Annual Health Care Conference. The event will take place on Wednesday, March 5, 2025, featuring a management fireside chat scheduled for 8:10 a.m. Central time.

Investors and interested parties can access a live audio webcast of the presentation through AbbVie's Investor Relations website at investors.abbvie.com. An archived version of the session will be made available for viewing later the same day.

AbbVie (NYSE: ABBV) announced that CEO Robert A. Michael will assume the additional position of chairman, effective July 1, 2025, following the retirement of current chairman Richard A. Gonzalez. The board of directors unanimously elected Michael to the position, with lead independent director Roxanne S. Austin expressing complete confidence in his leadership.

Gonzalez, who has served as chairman since AbbVie's formation in 2013 and was formerly the company's CEO, will retire from the board. Additionally, Glenn F. Tilton, who served as lead independent director from 2013 to 2024, will also retire from AbbVie's board effective July 1, 2025.

AbbVie (NYSE: ABBV) has announced a quarterly cash dividend of $1.64 per share, payable on May 15, 2025, to stockholders of record as of April 15, 2025. The company has demonstrated strong dividend growth, increasing its dividend by 310 percent since its establishment in 2013. AbbVie maintains its position in the prestigious S&P Dividend Aristocrats Index, which recognizes companies with at least 25 consecutive years of dividend increases.

Allergan Aesthetics, an AbbVie company (NYSE: ABBV), announced plans to open three new Allergan Medical Institute (AMI) Training Centers in the United States. The centers will be located in Irvine, California, Atlanta, and Austin, with the first facility opening in 2025 at the company's headquarters in Orange County.

The training centers will provide comprehensive education programs for licensed aesthetics providers, focusing on clinical techniques, complications management, and business operations. Led by AMI Medical Director Dr. Saami Khalifian, the facilities will offer hands-on curriculum and learning experiences for providers at all experience levels.

The initiative expands AMI's global presence to more than ten locations worldwide. In November 2024, the company launched AMI Business Education on their online platform, offering free business operations courses to practitioners.

AbbVie (ABBV) and Xilio Therapeutics (XLO) have announced a collaboration and option-to-license agreement to develop novel tumor-activated immunotherapies. The partnership leverages Xilio's proprietary technology platform for developing tumor-activated biologics, including masked T-cell engagers.

The collaboration aims to combine AbbVie's oncology expertise with Xilio's technology to create next-generation cancer treatments focused on tumor-selective activation while minimizing systemic adverse events. Under the agreement terms, Xilio will receive $52.0 million in total upfront payments, including a $10.0M equity investment, and will be eligible for up to $2.1 billion in contingent payments plus tiered royalties.

AbbVie (ABBV) has received FDA approval for EMBLAVEO™, the first and only fixed-dose, intravenous, monobactam/β-lactamase inhibitor combination antibiotic. The drug is approved in combination with metronidazole for treating complicated intra-abdominal infections (cIAI) in adults with or no alternative options.

EMBLAVEO combines aztreonam and avibactam to combat Gram-negative bacteria, including resistant strains that produce Metallo-β-lactamases (MBLs). The approval was supported by the Phase 3 REVISIT study and prior findings on aztreonam's efficacy in cIAI treatment.

The drug received FDA's Qualified Infectious Disease Product (QIDP) Designation and Fast Track Designation in 2019, granting priority review and five-year regulatory exclusivity extension. Commercial availability is expected in Q3 2025.

Allergan Aesthetics, an AbbVie company (NYSE: ABBV), has announced a nationwide open casting call for the Faces of Natrelle® campaign, seeking women who have undergone breast reconstruction or augmentation to share their stories. The initiative, running through February 28, 2025, extends the Natrelle® For Every BODY platform and aims to promote inclusivity and diversity.

Natrelle®, recognized as the #1 selected breast implant by leading U.S. physicians, offers the largest range of breast implant options. The campaign targets women aged 22 or older who have recently scheduled or undergone Natrelle® procedures. Important safety information highlights that breast implants are not lifetime devices and may require additional surgeries due to complications, including risks of BIA-ALCL cancer and various systemic symptoms.