AbbVie Inc. reports pharmaceutical developments across immunology, neuroscience, oncology and Allergan Aesthetics. Recurring updates include financial results by product portfolio, clinical and real-world data for therapies such as SKYRIZI and RINVOQ, FDA regulatory submissions and response letters, and medical-conference presentations in inflammatory bowel disease and other immune-mediated conditions.
Company news also covers pipeline spending, acquired in-process research and development, manufacturing capacity for medicines in core therapeutic areas, and investor conference appearances. AbbVie’s product references commonly include SKYRIZI, RINVOQ, Botox Therapeutic, Vraylar, Ubrelvy, Qulipta, Venclexta, Imbruvica and Elahere.
AbbVie (NYSE: ABBV) presented new data from the Phase 2 CAPTIVATE trial at the 2020 ASH Annual Meeting, showcasing the efficacy of IMBRUVICA® (ibrutinib) combined with VENCLEXTA®/VENCLYXTO® (venetoclax) for treating chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). The results indicated a one-year disease-free survival (DFS) rate of 100% for patients receiving ibrutinib compared to 95.3% for placebo. This combination also demonstrated high rates of undetectable minimal residual disease (uMRD). The study's findings support a potential fixed-duration treatment option for CLL/SLL patients.
AbbVie and Frontier Medicines announced a strategic collaboration to discover and develop innovative small molecule therapeutics targeting challenging protein targets in oncology and immunology. AbbVie will provide an upfront payment of $55 million and cover R&D costs during pre-clinical development phases. The collaboration has the potential for milestone payments exceeding $1 billion and expanded target options. AbbVie aims to enhance its efforts in targeted protein degradation while Frontier retains rights to its internal programs.
AbbVie (NYSE: ABBV) and Frontier Medicines have entered a strategic collaboration aimed at discovering and commercializing small molecule therapeutics targeting challenging protein targets, especially in oncology and immunology.
AbbVie will provide an upfront payment of $55 million and cover Frontier's R&D costs through early development phases. Frontier can receive additional milestone payments, potentially exceeding $1 billion, as well as royalties on commercialized products. This partnership enhances AbbVie's focus on innovative drug development, particularly in protein degradation.
AbbVie will conduct a virtual immunology strategic update for investors on December 14, 2020, at 9:00 a.m. Central time. Richard A. Gonzalez, CEO, alongside the executive leadership team, will discuss AbbVie's immunology business and pipeline. Investors can access a live audio webcast on AbbVie's Investor Relations site, with an archived version available later that day. AbbVie's mission focuses on developing innovative medicines across various therapeutic areas, including immunology, oncology, and more.
AbbVie (NYSE: ABBV) will participate in the Evercore ISI Virtual HealthCONx Conference on December 2, 2020, at 1:40 p.m. CT, and the Piper Sandler Virtual Healthcare Conference on December 3, 2020, at 10 a.m. CT. Key executives, including Michael Severino, M.D., and Robert A. Michael, will present at both venues. Investors can access a live audio webcast from AbbVie's Investor Relations website, with archived versions available later that day. AbbVie's mission focuses on delivering innovative medicines across various therapeutic areas.
AbbVie announced the expiration and results of its Registered Exchange Offers for its outstanding senior unsecured notes totaling $30 billion and €2.5 billion. The offers concluded on November 17, 2020, with an impressive participation rate across multiple notes, notably a 100% exchange of the Senior Floating Rate Notes due November 2021. The company is set to settle the exchanges on November 19, 2020. The new Registered Notes will have similar terms to the Original Notes but will be registered under the Securities Act, eliminating certain transfer restrictions.
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AbbVie will participate in the Wolfe Research Healthcare Conference on November 19, 2020. Presenters include Michael Severino, vice chairman and president, and Robert A. Michael, CFO, scheduled for 11:35 a.m. Central time. A live audio webcast will be available on AbbVie’s Investor Relations website, with an archived version accessible later the same day.
AbbVie focuses on delivering innovative medicines across various therapeutic areas, including immunology and oncology.
AbbVie (NYSE: ABBV) will present nearly 40 abstracts, including 10 oral presentations, at the virtual American Society of Hematology (ASH) Annual Meeting from December 5-8, focusing on blood cancers.
Key studies include updated results from the CAPTIVATE study on chronic lymphocytic leukemia (CLL) treatments and data from collaborations with Genmab and I-Mab. Notable presentations involve long-term efficacy analyses and real-world patient data on therapies like Ibrutinib and Venetoclax.
AbbVie reported third-quarter 2020 financial results with net revenues of $12.902 billion, a 52.1% increase. Adjusted net revenues were $12.882 billion, up 4.1%. The company highlighted growth from key products like Skyrizi and Rinvoq. Humira net revenues were $5.140 billion, with a 4.1% increase. Rinvoq and Venclexta received FDA applications for new indications. EPS reached $1.29 (GAAP) and $2.83 (adjusted). AbbVie announced a 10.2% dividend increase, reflecting a commitment to shareholder returns.