Welcome to our dedicated page for Acadia Pharmaceuticals news (Ticker: ACAD), a resource for investors and traders seeking the latest updates and insights on Acadia Pharmaceuticals stock.
Acadia Pharmaceuticals Inc. develops and commercializes therapies for neurological and rare diseases. Its commercial portfolio includes NUPLAZID (pimavanserin) for hallucinations and delusions associated with Parkinson’s disease psychosis and DAYBUE (trofinetide), including DAYBUE STIX, for Rett syndrome.
Company news commonly covers product revenue from NUPLAZID and DAYBUE, formulation and launch updates for trofinetide, clinical and scientific presentations across neurological disorders, pipeline work in Alzheimer’s disease psychosis, Lewy body dementia psychosis and essential tremor, investor-conference participation, and board or research-and-development leadership changes.
Acadia Pharmaceuticals (NASDAQ: ACAD) will present at the 11th Annual SVB Leerink Global Healthcare Conference on February 18, 2022, at 1:40 p.m. ET. The event will be held virtually, with a live webcast available on Acadia's website under the investors section. An archived recording will be accessible until March 18, 2022. Acadia focuses on neuroscience breakthroughs, having developed the first approved treatment for Parkinson’s disease psychosis and is advancing therapies for dementia-related psychosis and other CNS disorders.
Acadia Pharmaceuticals and Stoke Therapeutics have formed a collaboration to co-develop RNA-based therapies for severe neurodevelopmental diseases, including SYNGAP1 syndrome and Rett syndrome. Acadia gains exclusive licenses for two additional preclinical programs. Stoke receives a $60 million upfront payment, with potential milestone payments reaching $907 million, along with royalties. The partnership combines Stoke’s TANGO research platform with Acadia’s development expertise, aiming to enhance treatment options for patients with these debilitating conditions.
Acadia Pharmaceuticals (Nasdaq: ACAD) announced its participation in the 40th Annual J.P. Morgan Healthcare Conference on January 11, 2022, at 10:30 a.m. Eastern Time. The event will be held virtually, featuring a live audio-only webcast of Acadia's presentation and Q&A session, which can be accessed on their website and will be available for replay until February 11, 2022.
Acadia focuses on advancing neuroscience breakthroughs, including treatments for psychosis related to Parkinson's disease, dementia, schizophrenia, and Rett syndrome.
Acadia Pharmaceuticals has announced plans to resubmit its supplemental New Drug Application (sNDA) for pimavanserin, aimed at treating hallucinations and delusions associated with Alzheimer's disease psychosis, in the first quarter of 2022. The resubmission will include new analyses from two positive Phase 3 studies, ultimately supporting its clinical benefits without worsening cognitive or motor functions in elderly patients. The company has had constructive discussions with the FDA regarding the resubmission process.
Acadia Pharmaceuticals Inc. has promoted Mark Schneyer to Executive Vice President and Chief Financial Officer (CFO), effective immediately. Schneyer, who served as interim CFO since September 2021, will oversee finance, accounting, investor relations, and business development. CEO Steve Davis expressed confidence in Schneyer’s leadership and experience, highlighting his role in strategic growth initiatives and the acquisition of CerSci Therapeutics. Schneyer joined Acadia in 2020 from Pfizer, bringing extensive experience in corporate finance and strategic transactions.
Acadia Pharmaceuticals announced positive results from its pivotal Phase 3 Lavender study of trofinetide for treating Rett syndrome in 187 girls and young women aged 5-20. The study met co-primary endpoints, showing statistically significant improvements in the Rett Syndrome Behaviour Questionnaire (p=0.0175) and Clinical Global Impression of Improvement (p=0.0030). Additionally, trofinetide improved a key secondary endpoint related to communication (p=0.0064). A pre-NDA meeting with the FDA is planned for Q1 2022, with an NDA submission expected mid-year.
Acadia Pharmaceuticals (ACAD) announced the publication of Phase 2 ADVANCE study results in The Lancet Psychiatry, which evaluated pimavanserin as an adjunctive treatment for schizophrenia's negative symptoms. The study demonstrated a significant improvement in negative symptoms from baseline to week 26 compared to placebo (-10.4 vs. -8.5; p=0.043). Pimavanserin was well-tolerated, with completion rates around 86%, and similar adverse event rates between groups. Acadia plans to continue evaluating pimavanserin in its Phase 3 ADVANCE-2 study.
Acadia Pharmaceuticals has launched Yours, Truly, a storytelling campaign aimed at raising awareness of non-motor symptoms in Parkinson’s disease during National Family Caregivers Awareness Month. This initiative, in collaboration with StoryCorps, enables participants to share personal stories, fostering understanding and reducing stigma. Approximately one million people in the U.S. live with Parkinson's, with around 50% experiencing psychotic symptoms. The campaign seeks to empower patients and caregivers by amplifying their voices and experiences.
Acadia Pharmaceuticals (Nasdaq: ACAD) reported 3Q21 net sales of $131.6 million, a 9% increase from $120.6 million in 3Q20. Net losses narrowed to $14.5 million from $84.7 million year-over-year. Acadia plans an FDA meeting to discuss a potential resubmission of the pimavanserin sNDA for dementia-related psychosis, with top-line results from the Phase 3 LAVENDER study for Rett syndrome expected by year-end. NUPLAZID sales guidance has been narrowed to $480-$500 million, while R&D guidance has been adjusted to $230-$245 million.
Acadia Pharmaceuticals has presented new analyses on Medicare claims data related to dementia-related psychosis (DRP) at Psych Congress 2021. The data shows that over 70% of patients treated with off-label atypical antipsychotics experienced adverse events within a year, with costs averaging $5,565 for hyperlipidemia. Additionally, approximately 38% of patients faced cerebrovascular adverse events, with associated costs soaring to $68,308. Furthermore, nearly two-thirds of patients experienced suboptimal treatment outcomes leading to higher annual costs.
Acadia emphasizes the urgent need for effective treatments for DRP.