Welcome to our dedicated page for Acadia Pharmaceuticals news (Ticker: ACAD), a resource for investors and traders seeking the latest updates and insights on Acadia Pharmaceuticals stock.
Acadia Pharmaceuticals Inc. develops and commercializes therapies for neurological and rare diseases. Its commercial portfolio includes NUPLAZID (pimavanserin) for hallucinations and delusions associated with Parkinson’s disease psychosis and DAYBUE (trofinetide), including DAYBUE STIX, for Rett syndrome.
Company news commonly covers product revenue from NUPLAZID and DAYBUE, formulation and launch updates for trofinetide, clinical and scientific presentations across neurological disorders, pipeline work in Alzheimer’s disease psychosis, Lewy body dementia psychosis and essential tremor, investor-conference participation, and board or research-and-development leadership changes.
Acadia Pharmaceuticals announced positive results from its pivotal Phase 3 Lavender study of trofinetide for treating Rett syndrome in 187 girls and young women aged 5-20. The study met co-primary endpoints, showing statistically significant improvements in the Rett Syndrome Behaviour Questionnaire (p=0.0175) and Clinical Global Impression of Improvement (p=0.0030). Additionally, trofinetide improved a key secondary endpoint related to communication (p=0.0064). A pre-NDA meeting with the FDA is planned for Q1 2022, with an NDA submission expected mid-year.
Acadia Pharmaceuticals (ACAD) announced the publication of Phase 2 ADVANCE study results in The Lancet Psychiatry, which evaluated pimavanserin as an adjunctive treatment for schizophrenia's negative symptoms. The study demonstrated a significant improvement in negative symptoms from baseline to week 26 compared to placebo (-10.4 vs. -8.5; p=0.043). Pimavanserin was well-tolerated, with completion rates around 86%, and similar adverse event rates between groups. Acadia plans to continue evaluating pimavanserin in its Phase 3 ADVANCE-2 study.
Acadia Pharmaceuticals has launched Yours, Truly, a storytelling campaign aimed at raising awareness of non-motor symptoms in Parkinson’s disease during National Family Caregivers Awareness Month. This initiative, in collaboration with StoryCorps, enables participants to share personal stories, fostering understanding and reducing stigma. Approximately one million people in the U.S. live with Parkinson's, with around 50% experiencing psychotic symptoms. The campaign seeks to empower patients and caregivers by amplifying their voices and experiences.
Acadia Pharmaceuticals (Nasdaq: ACAD) reported 3Q21 net sales of $131.6 million, a 9% increase from $120.6 million in 3Q20. Net losses narrowed to $14.5 million from $84.7 million year-over-year. Acadia plans an FDA meeting to discuss a potential resubmission of the pimavanserin sNDA for dementia-related psychosis, with top-line results from the Phase 3 LAVENDER study for Rett syndrome expected by year-end. NUPLAZID sales guidance has been narrowed to $480-$500 million, while R&D guidance has been adjusted to $230-$245 million.
Acadia Pharmaceuticals has presented new analyses on Medicare claims data related to dementia-related psychosis (DRP) at Psych Congress 2021. The data shows that over 70% of patients treated with off-label atypical antipsychotics experienced adverse events within a year, with costs averaging $5,565 for hyperlipidemia. Additionally, approximately 38% of patients faced cerebrovascular adverse events, with associated costs soaring to $68,308. Furthermore, nearly two-thirds of patients experienced suboptimal treatment outcomes leading to higher annual costs.
Acadia emphasizes the urgent need for effective treatments for DRP.
Acadia Pharmaceuticals (NASDAQ: ACAD) announced the promotion of Brendan Teehan to Executive Vice President and Chief Operating Officer, effective immediately. Previously the Senior Vice President, Chief Insights and Analytics Officer, Teehan will oversee all sales and marketing functions while continuing to lead commercial strategy and operations. Teehan has over 25 years of experience in healthcare, having worked with companies like Johnson & Johnson and Amgen. Additionally, two senior executives, Charmaine Lykins and Amanda Morgan, will leave the company for new opportunities.
Acadia Pharmaceuticals will report its third quarter 2021 financial results on November 8, 2021, after the market closes. A conference call and webcast will follow at 4:30 p.m. Eastern Time on the same day, providing insights into the company's financials and operations. Participants can access the call via dedicated numbers for U.S. and international callers. The event will also be available for replay until November 22, 2021. Acadia continues to focus on innovative solutions in neuroscience.
Acadia Pharmaceuticals (NASDAQ: ACAD) announced a scientific presentation on pimavanserin at the 14th Clinical Trials on Alzheimer’s Disease (CTAD) conference, scheduled for November 9-12, 2021, in Boston, MA. A poster presentation will summarize post-hoc analysis results from the Phase 3 HARMONY trial, focusing on treating hallucinations and delusions in patients with Parkinson’s disease dementia. Although pimavanserin is FDA-approved for Parkinson’s disease psychosis, it is not approved for dementia-related psychosis.
Acadia Pharmaceuticals Inc. (NASDAQ: ACAD) will participate in several upcoming virtual investor conferences, including the Citi’s 16th Annual BioPharma Virtual Conference on September 10, 2021, Morgan Stanley Virtual 19th Annual Global Healthcare Conference on September 13, 2021, and the 2021 Cantor Virtual Global Healthcare Conference on September 27, 2021. Live webcasts will be accessible on the company’s website under the investors section, with archived recordings available for a month post-event.
Acadia Pharmaceuticals (Nasdaq: ACAD) announced the departure of Elena Ridloff, Chief Financial Officer, effective September 10, 2021, as she transitions to another biopharmaceutical firm. Mark Schneyer, Senior VP of Business Development, will serve as interim CFO while a formal search for a new CFO is conducted. CEO Steve Davis expressed gratitude for Ridloff's contributions to Acadia's growth and the pimavanserin franchise.