AC Immune Stock Price, News & Analysis

AC Immune SA (NASDAQ: ACIU) reported Q3 2020 financial results, achieving revenues of CHF 1.1 million amid a significant decline of CHF 32.1 million year-over-year. The company holds CHF 246.6 million in cash, funding operations until Q1 2024. A Phase 1 trial with Eli Lilly for Morphomer™ Tau showed promising pharmacokinetics, while the TDP-43 therapeutic program advances with EU grant support. However, a Phase 2 trial of the anti-Tau antibody did not meet primary efficacy endpoints. R&D expenditures increased by over 35%, and the net loss for Q3 reached CHF 19 million.

AC Immune (NASDAQ: ACIU), a leading biopharmaceutical company focused on neurodegenerative diseases, announced its participation in the Jefferies Virtual London Healthcare Conference on November 18, 2020. CEO Prof. Andrea Pfeifer will discuss the company’s strategies for 2021, particularly its candidates targeting TAR DNA-binding protein 43 (TDP-43), which is critical in conditions like Alzheimer’s and amyotrophic lateral sclerosis (ALS). The presentation aims to highlight their innovative approach to precision medicine in treating these diseases.

AC Immune SA has entered a strategic partnership with WuXi Biologics to advance its TDP-43 antibody into clinical development for NeuroOrphan indications. This agreement leverages AC Immune's drug discovery platforms and WuXi's manufacturing capabilities to address the significant unmet medical needs related to TDP-43-related neurodegenerative diseases. The collaboration aims to expedite the drug development process, with AC Immune retaining all intellectual property rights. This partnership highlights the company's growth and commitment to bringing innovative treatments to market.

AC Immune (NASDAQ: ACIU) has secured a €1.45M grant from the EU's Joint Programme – Neurodegenerative Disease Research (JPND). This funding will support the development of the first-in-class TDP-43 PET tracer in collaboration with the JPND ImageTDP-43 consortium, aimed at detecting neurodegenerative diseases including ALS and FTLD-TDP. The company emphasizes its innovative Morphomer™ platform's role in advancing precision medicine, as highlighted by CEO Prof. Andrea Pfeifer. The TDP-43 PET tracer shows strong binding to pathological aggregates, enhancing diagnostics and potential treatments for Alzheimer’s disease.

AC Immune (NASDAQ: ACIU) announced its participation in the H.C. Wainwright 22nd Annual Global Investment Conference on September 15, 2020. CEO Prof. Andrea Pfeifer will present the company’s advanced anti-Tau clinical pipeline, which includes an antibody, a small molecule inhibitor, and a vaccine targeting neurodegenerative diseases. The presentation will highlight recent results from their Tau PET imaging agent, PI-2620, which may aid in earlier diagnosis of progressive supranuclear palsy (PSP). Four clinical-stage assets are in development.

AC Immune SA (NASDAQ: ACIU) announced the start of investigational new drug (IND)-enabling studies for its first-in-class anti-TDP-43 antibody, which is the only antibody reported to have in vivo activity against TDP-43 neuropathology. This antibody targets various neurodegenerative conditions, including ALS and FTLD-TDP, associated with significant market potential. The initiative follows several key achievements in the company’s pipeline, which utilizes the proprietary SupraAntigen™ and Morphomer™ platforms. CEO Andrea Pfeifer emphasized the importance of this milestone in addressing unmet needs in neurodegenerative diseases.

AC Immune (NASDAQ: ACIU) presented innovative data for its next-generation alpha-synuclein PET tracer at the Alzheimer’s Association International Conference (AAIC) on July 28, 2020. The preclinical results highlight improved contrast and specificity for diagnosing Parkinson’s disease, meeting a significant clinical need. The company’s Morphomer™ platform is key to developing these diagnostics. ACI-12589 shows promise as a first-class imaging agent, advancing the company's therapeutic and diagnostic strategies for neurodegenerative diseases, particularly alpha-synucleinopathies.

AC Immune (NASDAQ: ACIU) announced that it will deliver two oral presentations at the Alzheimer’s Association International Conference (AAIC), running virtually from July 27 to 31, 2020. The presentations will cover the company's advancements in the alpha-synuclein PET tracer program and the Phase 1b trial of the ACI-24 anti-Abeta vaccine in Down syndrome. These presentations highlight AC Immune’s innovative pipeline targeting neurodegenerative diseases and confirm its commitment to pioneering diversified approaches in Alzheimer’s treatment.