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Actuate Therapeutics to Present at The Citizens Life Sciences Conference

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Actuate Therapeutics (NASDAQ: ACTU) announced that Dan Schmitt, President & CEO, will present at the Citizens Life Sciences Conference in Miami Beach on March 10, 2026 at 8:25 a.m. ET. The presentation will be webcast and available live under "Events" in Investors at the company website.

A replay will be available on Actuate's website for 30 days after the presentation, and management will hold one-on-one meetings with registered attendees.

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Positive

  • None.

Negative

  • None.

Key Figures

Conference date: March 10, 2026 Presentation time: 8:25 a.m. ET Webcast replay window: 30 days +5 more
8 metrics
Conference date March 10, 2026 Citizens Life Sciences Conference presentation
Presentation time 8:25 a.m. ET Scheduled start of CEO presentation
Webcast replay window 30 days Replay availability on company website
Share price $3.05 Price before Citizens conference news
Daily price change -18.4% Move over prior 24 hours pre-announcement
Today’s volume 218,514 shares Trading volume on news date
20-day avg volume 42,334 shares Baseline for volume comparison
52-week range $3.02–$11.99 Low and high prior to this announcement

Market Reality Check

Price: $3.05 Vol: Volume 218,514 is 5.16x t...
high vol
$3.05 Last Close
Volume Volume 218,514 is 5.16x the 20-day average of 42,334, indicating unusually heavy trading ahead of this conference update. high
Technical Shares at $3.05 are 74.56% below the 52-week high of $11.99 and only 0.99% above the 52-week low of $3.02, trading below the 200-day MA of $6.9.

Peers on Argus

ACTU fell 18.4% while key biotech peers showed mixed moves (e.g., CRDF up 4.21%,...
1 Up

ACTU fell 18.4% while key biotech peers showed mixed moves (e.g., CRDF up 4.21%, AVTX down 2.96%, GLSI down 1.85%). Only one peer (INO) appeared in the momentum scanner, moving up, which does not support a coordinated sector decline.

Historical Context

5 past events · Latest: Feb 24 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Feb 24 Investor conference Positive +10.6% Oppenheimer healthcare conference presentation with webcast and investor meetings.
Jan 21 Clinical pipeline plan Positive +5.4% Plan to start Phase 1/2 elraglusib tablet trial in refractory cancers.
Jan 12 Phase 2 survival data Positive -6.3% Phase 2 elraglusib plus GnP met primary endpoint in pancreatic cancer.
Jan 06 Pediatric Phase 1 data Positive +5.0% Positive outcomes in refractory pediatric cancers with elraglusib combinations.
Dec 18 ASCO GI selection Positive +2.3% Phase 2 pancreatic data selected for oral and poster presentation at ASCO GI.
Pattern Detected

Recent Actuate news has generally been positive and often followed by gains, with one notable divergence on favorable Phase 2 data.

Recent Company History

Over the last few months, Actuate has combined clinical progress with investor outreach. Positive clinical updates for elraglusib in metastatic pancreatic cancer and refractory pediatric cancers in January 2026 drove mixed price reactions, including a -6.35% move after strong Phase 2 survival data and gains of 5.4%, 5.05%, and 2.33% on other clinical milestones. A recent conference appearance on February 26, 2026 coincided with a 10.64% rise. Today’s Citizens Life Sciences Conference presentation continues this pattern of active visibility efforts.

Regulatory & Risk Context

Active S-3 Shelf
Shelf Active
Active S-3 Shelf Registration 2025-09-02

The company has an active Form S-3 shelf registration filed on 2025-09-02, allowing it to offer various securities such as common stock, debt, warrants, and units in the future. Specific offering terms and sizes are defined in subsequent prospectus supplements, with at least 2 such supplements (both Form 424B5) already filed.

Market Pulse Summary

This announcement highlights continued investor-relations activity, with Actuate presenting at the C...
Analysis

This announcement highlights continued investor-relations activity, with Actuate presenting at the Citizens Life Sciences Conference on March 10, 2026 and offering a 30-day webcast replay. It follows recent clinical updates in pancreatic and pediatric cancers and another conference appearance in late February. Investors watching the story may focus on how these events support capital access, including use of the active S-3 shelf filed on 2025-09-02, and on future clinical milestones for elraglusib.

Key Terms

glycogen synthase kinase-3 beta (gsk-3β)
1 terms
glycogen synthase kinase-3 beta (gsk-3β) medical
"…through the inhibition of glycogen synthase kinase-3 beta (GSK-3β), today announced…"
Glycogen synthase kinase-3 beta (GSK-3β) is a cellular enzyme that acts like a control knob for many internal processes such as energy storage, cell survival and signaling. It matters to investors because drugs that block or modify this enzyme are potential treatments for conditions like neurodegenerative diseases, certain cancers and metabolic disorders, so progress or setbacks in related research can strongly affect the value and prospects of biotech companies.

AI-generated analysis. Not financial advice.

CHICAGO and FORT WORTH, Texas, March 04, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers through the inhibition of glycogen synthase kinase-3 beta (GSK-3β), today announced that Dan Schmitt, President & CEO of the Company, will present at the Citizens Life Sciences Conference in Miami Beach, FL on Tuesday, March 10, 2026, at 8:25 a.m. ET.

The webcast of Mr. Schmitt’s presentation will be available at:

https://event.summitcast.com/view/BuMiPNPtyHKimMF6k4AFMd/guest_book?session_id=PW9gAwrMfrWWSf34Hno6ah

The Actuate management team will be available for one-on-one meetings with registered conference attendees.

A live link to the presentation will be located under “Events” in the Investors section of the Company’s website at www.actuatetherapeutics.com. A replay of the webcast will be available on Actuate’s website for 30 days following the presentation.

About Actuate Therapeutics, Inc.

Actuate is a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers. Actuate’s lead investigational drug, elraglusib (a novel GSK-3β inhibitor), targets molecular pathways in cancer that are involved in promoting tumor growth and resistance to conventional cancer drugs such as chemotherapy through the inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) and DNA Damage Response (DDR). Elraglusib may also mediate anti-tumor immunity through the regulation of multiple immune checkpoints and immune cell function.

For additional information, please visit the Company’s website at www.actuatetherapeutics.com or follow us on LinkedInX, and Facebook.

Forward Looking Statements

This press release contains forward-looking statements about us, including our and other parties’ clinical trials and development plans, and our industry. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “ongoing,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would,” or the negative of these terms or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. All statements, other than statements related to present facts or current conditions or of historical facts, contained in this press release are forward-looking statements. Accordingly, these statements involve estimates, assumptions, substantial risks and uncertainties which could cause actual results to differ materially from those expressed in them, including but not limited to that preliminary and unpublished data may be subject to change and further interpretation following the availability of more data or following a more comprehensive review of the data and should not be relied upon as a final analysis; clinical and preclinical drug development involves a lengthy and expensive process with uncertain timelines and outcomes, results of prior preclinical studies, early clinical trials and sub-group studies are not necessarily predictive of future results and may not correlate with improved responses, and elraglusib may not achieve positive clinical results or favorable preclinical results or receive regulatory approval on a timely basis, if at all; that we may not successfully enroll additional patients or establish or advance plans for further development, including through conversations with the FDA or EMA and the standards such bodies may impose for such development; that elraglusib could be associated with side effects, adverse events or other properties or safety risks, which could delay or preclude regulatory approval, cause us to suspend or discontinue clinical trials or result in other negative consequences; our reliance on third parties to conduct our non-clinical studies and our clinical trials; our reliance on third-party licensors and ability to preserve and protect our intellectual property rights; that we face significant competition from other biotechnology and pharmaceutical companies; our ability to fund development activities, including because our financial condition raises substantial doubt as to our ability to continue as a going concern and we require additional capital to finance our operations beyond the second quarter of fiscal year 2026, and a failure to obtain this necessary capital in the near term on acceptable terms, or at all, could force us to delay, limit, reduce or terminate our development programs, commercialization efforts or other operations. In addition, any forward-looking statements are qualified in their entirety by reference to the factors discussed under the heading “Item 1A. Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 13, 2025, and our Quarterly Reports on Form 10-Q, and other filings with the SEC. Because the risk factors referred to above could cause actual results or outcomes to differ materially from those expressed in any forward-looking statements made by us or on our behalf, you should not place undue reliance on any forward-looking statements. Further, any forward-looking statement speaks only as of the date on which it is made. New factors emerge from time to time, and it is not possible for us to predict which factors will arise. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. Unless legally required, we do not undertake any obligation to release publicly any revisions to such forward-looking statements to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events.

Investor Contact
Mike Moyer
Managing Director
LifeSci Advisors, LLC
mmoyer@lifesciadvisors.com

Media Contact
Ignacio Guerrero-Ros, Ph.D.
Russo Partners, LLC
Ignacio.guerrero-ros@russopartnersllc.com
(858) 717-2310


FAQ

When will Actuate Therapeutics (ACTU) present at the Citizens Life Sciences Conference?

Actuate will present on March 10, 2026 at 8:25 a.m. ET. According to the company, Dan Schmitt, President & CEO, will deliver the presentation in Miami Beach and management will be available for one-on-one meetings with registered attendees.

How can investors watch the ACTU presentation at the March 10, 2026 conference?

Investors can watch via a live webcast linked under Events on the company website. According to the company, a direct webcast URL is provided and the live link will also appear in the Investors section for easy access.

Will Actuate Therapeutics (ACTU) provide a replay of the Citizens Life Sciences presentation?

Yes, a replay will be available for 30 days after the presentation. According to the company, the webcast replay will be posted on Actuate's website so investors who miss the live event can view it within that 30-day window.

Who from Actuate will present at the Citizens Life Sciences Conference on March 10, 2026?

Dan Schmitt, President & CEO of Actuate, will present at the conference. According to the company, Mr. Schmitt will deliver the prepared remarks and the management team will offer one-on-one meetings with registered conference participants.

Where will the live webcast of Actuate Therapeutics (ACTU) be hosted for the conference presentation?

The live webcast will be hosted on Actuate's investor website under Events and via a webcast URL. According to the company, the presentation link will be posted on the Investors section and the provided event URL will stream the talk live.
Actuate Therapeutics Inc

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