Adc Therapeutics Sa Stock Price, News & Analysis

ADC Therapeutics (NYSE:ADCT), a commercial-stage leader in antibody drug conjugates (ADCs), announced its upcoming participation in the Cantor Global Healthcare Conference 2025. CEO Ameet Mallik will engage in a fireside chat on September 3, 2025, at 9:10 a.m. ET.

Investors can access the presentation through a webcast on the Events & Presentations page of ADC Therapeutics' investor relations website. The webcast recording will remain available for approximately 30 days after the event.

ADC Therapeutics (NYSE:ADCT) reported Q2 2025 financial results and operational updates, highlighting significant progress in their ZYNLONTA® clinical programs. The company's LOTIS-7 trial showed impressive results with 93.3% overall response rate and 86.7% complete response rate in combination with glofitamab for r/r DLBCL patients.

Key financial developments include a $100 million PIPE financing, extending cash runway into 2028, and Q2 2025 net product revenues of $18.1 million. The company reported a net loss of $56.6 million ($0.50 per share). A strategic restructuring plan was announced, reducing global workforce by 30% and discontinuing early development efforts in solid tumors to focus on ZYNLONTA.

The LOTIS-5 Phase 3 trial is expected to reach PFS events by end-2025, with potential sBLA submission in H1 2026. The company's cash position stands at $264.6 million as of June 30, 2025.

ADC Therapeutics (NYSE: ADCT), a commercial-stage leader in antibody drug conjugates, will host its Q2 2025 financial results conference call on August 12, 2025, at 8:30 a.m. EDT. The company will present financial results and provide business updates during the call.

Investors can access the conference via toll-free dial-in at 1-800-836-8184 for North America and Canada. A live webcast will be available on the company's investor relations website, with the recording accessible for 30 days after the event.

ADC Therapeutics (NYSE: ADCT), a commercial-stage leader in antibody drug conjugates, has granted stock options for 127,000 common shares to three new employees as employment inducement awards. The grants were approved by the Company's Compensation Committee under the Inducement Plan.

The options will vest over a four-year period, with 25% vesting on the first anniversary and the remaining vesting monthly thereafter, contingent on continued employment. These grants were made under NYSE's Listed Company Manual Rule 303A.08 employment inducement exemption.

ADC Therapeutics (NYSE: ADCT), a commercial-stage leader in antibody drug conjugates, has granted stock options for 17,000 common shares to one new employee as an employment inducement. The grant was approved by the Company's Compensation Committee under the Inducement Plan.

The options will vest over a four-year period, with 25% vesting on the first anniversary and the remaining vesting monthly thereafter, contingent on continued employment. This grant was made under NYSE's Listed Company Manual Rule 303A.08 employment inducement exemption.

ADC Therapeutics announced updated Phase 2 trial data for ZYNLONTA in treating relapsed/refractory marginal zone lymphoma (r/r MZL) at ICML 2025. The trial showed impressive results with an 84.6% overall response rate and 69.2% complete response rate among 26 evaluable patients. Notably, 17 of 18 patients maintained complete response, with the longest duration being 27 months. The progression-free survival rate was 92.9% at 12 months. The treatment demonstrated a manageable safety profile, with mostly grade 1 or 2 adverse events. The study is expanding to additional sites to increase enrollment to 50 patients, and ADC Therapeutics plans to pursue regulatory pathways based on continued positive results.

ADC Therapeutics (NYSE: ADCT) has secured a $100 million PIPE financing through the sale of 13.0 million common shares at $3.53 per share and pre-funded warrants for 15.7 million shares at $3.43 each. The funding will support ZYNLONTA's clinical development and commercialization. The company plans significant restructuring, including a 30% workforce reduction and UK facility closure, incurring $6-7 million in restructuring charges. This extends their cash runway into 2028. Key upcoming catalysts include LOTIS-7 trial data expansion, LOTIS-5 Phase 3 trial results, potential regulatory submissions, and advancement of their PSMA-targeting ADC program. The PIPE financing, led by Redmile Group, is expected to close on June 16, 2025.

ADC Therapeutics announced updated data from the LOTIS-7 Phase 1b trial evaluating ZYNLONTA in combination with glofitamab for relapsed/refractory DLBCL patients. The combination demonstrated remarkable efficacy with a 93.3% overall response rate and 86.7% complete response rate among 30 evaluable patients. Notably, 25 of 26 patients achieving complete response maintained it at data cutoff. The treatment showed a manageable safety profile across 41 safety-evaluable patients, with main grade 3+ adverse events including neutropenia (24.4%) and anemia (9.8%). Based on these promising results, the company is expanding the trial enrollment to 100 patients at the 150 µg/kg dose level.

ADC Therapeutics (NYSE: ADCT) has granted stock options to two new employees totaling 107,550 common shares as part of their employment inducement package. The grants, approved by the Company's Compensation Committee under the Inducement Plan, were made on June 2, 2025. The options will vest over a four-year period, with 25% vesting on the first anniversary and the remaining vesting monthly at a rate of 1/48th, contingent on continued employment. The grants were made in compliance with NYSE's Listed Company Manual Rule 303A.08 and aim to motivate high performance and significant contributions to the company's success.