Aditxt Inc - ADTX STOCK NEWS

Aditxt (NASDAQ: ADTX) announced that its subsidiary Pearsanta has received IRB approval to begin a clinical study for the Mitomic® Endometriosis Test (MET), a blood-based diagnostic tool for endometriosis detection. The study will evaluate MET's performance against laparoscopic diagnosis, enrolling up to 1,000 participants starting May 2025.

The study aims to assess MET's sensitivity and specificity across disease subtypes, explore correlations between test results and symptoms, and establish a biobank for future research. MET utilizes mitochondrial DNA biomarkers to detect disease signatures through a simple blood draw, potentially offering a non-invasive alternative to surgical diagnosis.

Endometriosis affects 1 in 10 women globally, with diagnosis typically taking 7-10 years due to current diagnostic limitations. The study results will support MET's launch as a Laboratory Developed Test at Pearsanta's CLIA/CAP-certified laboratory in Richmond, Virginia.

Aditxt (NASDAQ: ADTX) announced positive results from Mayo Clinic pre-clinical studies for its subsidiary Adimune's lead therapeutic candidate ADI-100. The study, led by Mayo Clinic's neuroimmunology team, validated that ADI-100 induces immune tolerance to glutamic acid decarboxylase (GAD), a key autoantigen in multiple autoimmune conditions.

Key findings include:

• Confirmation of ADI-100's safety profile with no increased T cell reactivity to GAD
• Dendritic cells treated with ADI-100 showed increased tolerogenic markers
• ADI-100-induced tolerogenic dendritic cells reduced activation of T cells from GAD-sensitive patients

The findings were presented at the American Academy of Neurology Annual Meeting. With pre-clinical efficacy and safety studies complete and GMP manufacturing finalized, Adimune plans regulatory submissions for the second half of 2025, targeting subsequent first-in-human clinical trials.

Aditxt (NASDAQ: ADTX), a social innovation platform focused on health innovations, has announced its Weekly Update event scheduled for today at 11:30 a.m. ET. The virtual meeting will address several key developments, including the company's recent achievement of regaining compliance with Nasdaq's minimum bid price requirement, ensuring continued listing on the Nasdaq Capital Market.

The event will also provide updates on the company's operating subsidiaries and discuss ongoing strategic transactions. The meeting will be held virtually via Zoom, with registration required for attendance.

Aditxt (NASDAQ: ADTX) has successfully regained compliance with Nasdaq's minimum bid price requirement under Listing Rule 5550(a)(2). As a result, the previously scheduled hearing before the Hearings Panel for April 22, 2025, has been cancelled. The company will continue trading on the Nasdaq Capital Market under the symbol ADTX.

The social innovation platform, focused on accelerating promising health innovations in areas including autoimmunity and cancer, received official notification from the Nasdaq Stock Market's Listing Qualifications Department confirming their compliance status.

Aditxt (NASDAQ: ADTX) announced that Appili Therapeutics' President and CEO Don Cilla will join Aditxt's Weekly Update on April 4, 2025. The event will focus on emerging infectious diseases and provide updates on the Appili transaction and operational highlights.

Key highlights include $117 million in submitted federal funding applications and Appili's track record of securing $33.2 million in prior government awards. The update will also cover modifications to the United States Air Force Academy Cooperative Agreement for ATI-1701, a biodefense vaccine candidate, featuring an increased General & Administrative overhead recovery rate that will be applied retroactively.

Aditxt Inc (NASDAQ: ADTX) announced a Weekly Update event focusing on its subsidiary Pearsanta's recent acquisition of the CaSe Platform, a proprietary technology based on adductomics. The platform is designed to detect early DNA changes that may lead to cancer-associated mutations and other illnesses.

The virtual event, scheduled for March 28, 2025, at 11:30 a.m. ET, will feature presentations from key figures including Dr. Shahrokh Shabahang (Aditxt's Chief Innovation Officer), Chris Mitton (Pearsanta's President), and Dr. Roger Giese (Co-Inventor of the CaSe Platform and Professor Emeritus at Northeastern University). The discussion will explore the platform's potential role in advancing early cancer detection and prevention efforts.

Evofem Biosciences (OTCQB: EVFM) reported its financial results for Q4 and full-year 2024, marking its fourth consecutive year of net sales growth. The company achieved $19.4 million in net sales for 2024, a 6% increase from 2023, primarily driven by PHEXXI® sales and improved gross-to-net ratio.

Key operational highlights include:

• Total operating expense reduced by 27% to $26.4 million (excluding SOLOSEC amortization)
• Sales and marketing expense at 47% of net sales for 2024, the best ratio since PHEXXI's launch
• Loss from operations improved by 57% to $7.7 million
• Revenue stream diversified through SOLOSEC® acquisition in July 2024

The company entered a fifth amendment to the merger agreement with Aditxt (NASDAQ: ADTX), requiring $1.5 million funding by April 7, 2025, and merger consummation by September 30, 2025. Additionally, Evofem partnered with Windtree Therapeutics to reduce PHEXXI manufacturing costs.

Aditxt (NASDAQ: ADTX) announced that its subsidiary Pearsanta has acquired key patents for adductomics-based DNA damage detection in a transaction valued at approximately $1 million, paid in Pearsanta Convertible Preferred Stock.

The acquisition enhances Pearsanta's cancer prevention diagnostic capabilities by combining with their proprietary Mitomic® Technology platform. The adductomics technology enables detection of DNA adducts - chemical modifications to DNA caused by carcinogens - which are early indicators of cancer risk. The platform will analyze urine, blood, or solid tissue samples to assess genomic instability before permanent mutations occur.

Over the next 2-3 years, Pearsanta plans to:

• Conduct clinical validation of the technology
• Submit regulatory applications for Laboratory Developed Tests (LDTs) and FDA pathways
• Scale operations within CLIA/CAP-certified laboratories
• Integrate adductomics-based screening into their precision oncology portfolio

Aditxt (NASDAQ: ADTX) provided a corporate update highlighting progress across its subsidiaries and strategic initiatives. The company announced the launch of Aditxt Weekly Updates starting March 21, 2025.

Key subsidiary updates include:

• Adimune™ is preparing IND applications for Stiff Person Syndrome with Mayo Clinic and Clinical Trial Applications for Type 1 Diabetes and Psoriasis in Germany
• Pearsanta™ is advancing toward commercial launch in H2 2025 for blood-based Prostate Cancer and Endometriosis tests, with Dominari Securities engaged for planned IPO
• Adivue™ plans to seek FDA renewal for Brain Scientific's EEG device

Strategic acquisition updates:

• Extended agreement with Appili Therapeutics through March 2025 with completed $250,000 payments
• Ongoing discussions with Evofem Biosciences for potential integration

The company recently implemented a reverse stock split to maintain Nasdaq compliance.