Agenus Stock Price, News & Analysis

Agenus Inc. (NASDAQ: AGEN) reported positive preliminary results from its Phase 1 trial of iNKT cell therapy aimed at patients with moderate to severe COVID-19 symptoms. Conducted by AgenTus Therapeutics, the trial showcased that 3 out of 4 intubated patients were discharged after treatment, and 2 patients were extubated within 24 hours of dosing. The company is currently in the dose escalation phase, with plans to initiate a Phase 2 trial by mid-2021, and data readouts expected by Q4 2021. Early results indicate good tolerance and potential benefits of the therapy for severely ill patients.

Agenus Inc. (NASDAQ: AGEN) has announced a clinical collaboration with Nelum Corp. to evaluate the combination of zalifrelimab, its anti-CTLA-4 antibody, and Nelum's NLM-001 with chemotherapy for first-line advanced pancreatic cancer. The trial aims to assess the safety and efficacy of this combination. Under the agreement, Agenus will supply zalifrelimab, while Nelum will sponsor and conduct the trial, expected to begin enrolling in the first half of 2021. This collaboration is seen as a strategic move to enhance the therapeutic potential of Agenus' pipeline.

Agenus Inc. (NASDAQ: AGEN) announced that Dr. Jennifer Buell, President and COO, and Dr. Steven O’Day, CMO, will participate in the B. Riley Securities’ Oncology Investor Conference on January 20-21, 2021. The conference will feature a fireside chat with Dr. Buell on January 21 from 10:30 am to 11:00 am, accessible via a live webcast. Additionally, both doctors will engage in a panel discussion on novel immunotherapies. Recorded replays will be available on Agenus' Events & Presentations page post-conference.

Agenus Inc. (NASDAQ: AGEN) announced an updated timeline for the Biologics License Application (BLA) filing of balstilimab, necessitated by FDA feedback for a 12-month follow-up on all trial patients and a 6-month follow-up on responders. Two late responses in the clinical trial prompted this strategy adjustment, with the BLA filing now expected in the first half of 2021. The company is also clarifying PD-L1 diagnostic requirements with the FDA. This follow-up will provide data on patients achieving durable disease stabilization through long-term therapy.

Agenus Inc. (NASDAQ: AGEN) has expanded its Phase 2 trial for AGEN1181 in colorectal cancer following a promising clinical response. A significant tumor reduction of 27% was observed in a patient, alongside disease stabilization in 19 out of 41 treated patients. The trial also reported four clinical responses and the potential to treat tumors traditionally unresponsive to immune therapies. The company aims to broaden the patient population benefiting from cancer immunotherapies through innovative combination approaches.

Agenus Inc. (NASDAQ: AGEN) announced Dr. Jennifer Buell, President and COO, will participate in a fireside chat at the Evercore ISI 3rd Annual HealthCONx Conference on December 3, 2020, from 10:55 AM to 11:15 AM EST. Dr. Buell is set to provide updates on clinical programs, specifically AGEN1181, and the company's overall progress. Interested individuals can register for the webinar in advance. A replay will be available post-event on the Agenus website's Events & Presentations page.

Agenus Inc. (NASDAQ: AGEN), an immuno-oncology firm, announced Dr. Jennifer Buell's participation in a fireside chat at the Jefferies 2020 Virtual London Healthcare Conference on November 17, 2020, from 4:25 PM - 4:55 PM GMT. This event will highlight the company’s innovative pipeline of immune therapies, including checkpoint antibodies and vaccines aimed at enhancing immune responses against cancer. Interested parties can register for the webinar and access a replay on the Agenus website.

Agenus Inc. (NASDAQ: AGEN) announced a webcast on November 16, 2020, featuring Dr. Steven O’Day and other key figures discussing AGEN1181 and its Ph1 trial results. Dr. O’Day will review initial responses in patients with microsatellite stable disease and implications of Treg depletion. Dr. Jennifer Buell and Dr. Dhan Chand will outline next steps for AGEN1181 and share insights on its other drug programs, including AGEN2373 and AgenT-797. Registration is available online, and a replay will be accessible on the Agenus website post-event.

Agenus Inc. (NASDAQ: AGEN) announced participation in the Virtual SITC 2020 Immuno-Oncology Event hosted by B. Riley on November 12, 2020. Key executives, including Dr. Steven O'Day and Dr. Jennifer Buell, will lead discussions on Next-Gen Checkpoint Inhibitors and Cell Therapy 2.0. The event includes two panels: The first from 1:00 PM to 2:00 PM ET, and the second from 2:00 PM to 3:00 PM ET. Interested parties can access replays via provided conference IDs.

Agenus focuses on immuno-oncology therapies designed to activate immune responses against cancer.