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Aeglea BioTherapeutics Announces Grants of Inducement Awards

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Aeglea BioTherapeutics, Inc. has announced the approval of stock options for six non-executive employees. The options allow the purchase of an aggregate of 729,600 shares of common stock at an exercise price of $11.43 per share. The options will vest over time, with one-fourth of the shares becoming exercisable on the first anniversary of each employee's start date.
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WALTHAM, Mass., Nov. 3, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (NASDAQ: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to transform the treatment of inflammatory bowel disease ("IBD"), today announced that Aeglea's independent Compensation Committee of the Board of Directors approved the grants of stock options to purchase an aggregate of 729,600 shares of common stock of Aeglea to six non-executive employees as equity inducement awards under the Aeglea BioTherapeutics, Inc. 2018 Equity Inducement Plan, as amended (the "2018 Plan"). The stock options were approved on October 30, 2023 and were material to each employee's acceptance of employment with Aeglea, in accordance with Nasdaq Listing Rule 5635(c)(4).

The stock options were granted with a 10-year term and an exercise price equal to $11.43, the closing price per share of Aeglea's common stock as reported by Nasdaq on November 1, 2023. The options granted to each employee shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee's start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Aeglea through the applicable vesting dates. The stock options are subject to the terms of the 2018 Plan.

About Aeglea BioTherapeutics
In June 2023, Aeglea completed its asset acquisition of Spyre Therapeutics, Inc. and shifted its disease focus to IBD. Aeglea is advancing a pipeline of antibody therapeutics with the potential to transform the treatment of IBD. Aeglea's approach combines novel antibody engineering, rational therapeutic combinations, and precision immunology with the goal of maximizing efficacy, safety, and convenience of treatments for IBD. The company is developing antibodies targeting α4β7, TL1A, and IL-23.

 

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SOURCE Aeglea BioTherapeutics, Inc.

Aeglea BioTherapeutics announced the approval of stock options for non-executive employees.

The stock options allow the purchase of an aggregate of 729,600 shares of common stock.

The exercise price of the stock options is $11.43 per share.

The stock options will vest over time, with one-fourth of the shares becoming exercisable on the first anniversary of each employee's start date.

The stock options have a 10-year term.
Aeglea BioTherapeutics Inc

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About AGLE

aeglea was founded in december of 2013 to develop engineered human enzymes invented in the laboratory of george georgiou, ph.d. of the university of texas at austin. the convergence of discovery and technology has created a significant opportunity for aeglea to impact both the treatment of inborn errors of metabolism and cancer. three drug candidates that degrade specific amino acids in the circulation are in development. for inborn errors of metabolism efforts are underway to normalize high arginine levels in patients who suffer from a gene mutation in the arginine degrading enzyme arginase1 and for patients who have mutations leading to excess levels of homocysteine. taking advantage of a cancer’s metabolic vulnerability and selectively killing only the tumor through deprivation of arginine, cysteine/cystine, and methionine are techniques in development for multiple oncology indications. coupling amino acid depletion therapy with the development of diagnostics for each oncology f