Akari Therapeutics Plc Stock Price, News & Analysis

Akari Therapeutics has appointed Dr. John F. Neylan, III, as Executive Vice President and Chief Medical Officer, effective immediately. Dr. Neylan brings over 20 years of experience in medical and clinical development, having previously led research efforts at several biotech firms, including Angion Biomedica and Keryx Biopharmaceuticals. His expertise will support Akari's advancement of nomacopan, currently in a Phase 3 trial for HSCT-TMA, and in pre-clinical research for geographic atrophy. This leadership change aims to strengthen clinical development and accelerate the company’s drug development pipeline.

Akari Therapeutics, Plc (Nasdaq: AKTX) announced its participation in the Sidoti November Virtual Micro-Cap Conference on November 9, 2022, with President and CEO Rachelle Jacques presenting at 1:45 PM Eastern time. The management team will also engage in scheduled 1:1 investor meetings. A recording of the presentation will be available on the company's website post-event. Akari focuses on therapies for autoimmune and inflammatory diseases, particularly its lead asset, investigational nomacopan, which targets complement C5 activation and leukotriene B4 activity.

Akari Therapeutics (Nasdaq: AKTX) received a Nasdaq Listing Qualifications letter stating it is non-compliant with the $1.00 minimum bid price requirement. The company has a 180-day compliance period ending April 24, 2023, to rectify this by maintaining a closing bid price of at least $1.00 for ten consecutive business days. Failure to comply may lead to potential delisting. Currently, there is no immediate effect on trading, and Akari’s shares will continue to trade under the symbol AKTX during this grace period.

Akari Therapeutics has successfully closed a registered direct offering and concurrent private placement, raising approximately $12.8 million. The funds will support the company's focused pipeline, particularly the Phase 3 Part A clinical trial of nomacopan for severe pediatric HSCT-TMA, with data expected in the first half of 2023. The company is also advancing the development of long-acting PAS-nomacopan for geographic atrophy. Despite recent financing success, net loss for Q2 2022 rose to approximately $5.7 million due to increased research and administrative costs.

Akari Therapeutics (Nasdaq: AKTX), a late-stage biotechnology firm focused on therapies for autoimmune diseases, will participate in the Cantor Oncology & HemOnc Conference on September 28, 2022. President and CEO Rachelle Jacques will address challenges in cell therapy during a panel at 9:00 a.m. Eastern time and will engage in 1:1 meetings with investors. Akari’s lead treatment, nomacopan, is under Phase 3 trials for severe pediatric hematopoietic stem cell transplant-related thrombotic microangiopathy, along with preclinical work on PAS-nomacopan for geographic atrophy.

Akari Therapeutics, Plc (Nasdaq: AKTX) announced a private placement for 15,000,000 American Depository Shares (ADSs) at $0.85 each, raising gross proceeds of approximately $12.75 million. The offering includes Series A and B Warrants, exercised at the same price with expiration dates in 2024 and 2029. Proceeds will fund Phase 3 trials for nomacopan targeting severe pediatric HSCT-TMA and a pre-clinical program for geographic atrophy. The closing of the offering is expected on September 14, 2022, pending customary conditions.

Akari Therapeutics (Nasdaq: AKTX) has announced a strategic shift to prioritize two key pipeline programs. The company will focus cash and resources on the Phase 3 clinical trial of nomacopan for severe pediatric HSCT-TMA, with initial data anticipated in H1 2023. Additionally, the promising pre-clinical program for PAS-nomacopan in geographic atrophy will receive attention following positive results. Conversely, Akari is discontinuing the clinical evaluation of nomacopan in bullous pemphigoid. This decision stems from a reassessment of timelines and costs to enhance pipeline value.

Akari Therapeutics (NASDAQ: AKTX) announced positive pre-clinical results for PAS-nomacopan aimed at treating geographic atrophy (GA) in dry age-related macular degeneration (dAMD), a condition with no current treatments. The studies highlighted tolerability and the potential for extended dosing intervals of over three months, which could ease patient burden. New pharmacokinetic measurements indicate improved half-life for the drug in the eye. CEO Rachelle Jacques emphasized the supportive data for advancing toward regulatory applications necessary for clinical trials by year-end.

Akari Therapeutics (NASDAQ: AKTX) recently announced significant progress in its clinical trials and financial results for Q1 2022. The Phase 3 Part A trial of nomacopan for severe pediatric HSCT thrombotic microangiopathy (TMA) has enrolled four out of seven planned patients. Additionally, ten sites have opened for the ARREST-BP Phase 3 trial in bullous pemphigoid (BP), aiming to enroll 48 patients. Financially, cash increased to approximately $16.7 million, with a net loss of $5.2 million. The company continues to advance pre-clinical programs for geographic atrophy in dAMD.