Aligos Therapeutics, Inc. Stock Price, News & Analysis

Aligos Therapeutics (Nasdaq: ALGS) reported its Q2 2022 financial results and recent progress in clinical studies. Key highlights include:

• Cash reserves of $159.3 million, sufficient to fund operations into H1 2024.
• Net loss reduced to $19.9 million, down from $29.8 million YoY.
• R&D expenses decreased to $16.5 million, primarily due to the wind-down of specific programs.
• Enrollment completed in multiple Phase 1 studies, including ALG-000184 and ALG-125755, with ongoing development of treatments for HBV and NASH.

Management remains optimistic about upcoming clinical trial applications.

Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical-stage biopharmaceutical company, will report its second quarter financial results on August 4, 2022, after U.S. market close. Founded in 2018, Aligos focuses on developing therapies for viral infections, particularly chronic hepatitis B and coronaviruses, as well as targeted treatments for liver diseases like nonalcoholic steatohepatitis (NASH). With a strategy built on deep expertise in drug development, Aligos aims to advance its pipeline of potentially best-in-class therapeutics.

Aligos Therapeutics (Nasdaq: ALGS) has initiated enrollment for a 12-week dosing cohort of HBeAg-positive chronic hepatitis B (CHB) patients in its ongoing Phase 1b study of ALG-000184. CEO Lawrence Blatt emphasized this as a crucial step towards evaluating ALG-000184's potential as a chronic suppressive therapy. Prior results indicated that the drug was well tolerated with promising antiviral activity. Data from this cohort is expected to be shared at a scientific conference in Q4 2022, aiming to assess longer-term dosing effectiveness against elevated viral levels.

Aligos Therapeutics (Nasdaq: ALGS) presented preliminary Phase 1 data from its chronic hepatitis B (CHB) and nonalcoholic steatohepatitis (NASH) programs at the 2022 European Association for the Study of the Liver Congress. Highlights include significant reductions in HBV DNA and RNA in CHB patients after 28 days of treatment with ALG-000184. Additionally, preliminary results for ALG-055009 in hyperlipidemia patients showed favorable pharmacokinetics and safety. Aligos aims for broader clinical trials and further data releases in Q3 2022.

Aligos Therapeutics announced its participation in the Metropolitan AntiViral Drug Accelerator (MAVDA), a consortium recently awarded a $65 million grant from the NIH and NIAID. MAVDA aims to develop novel antiviral treatments for SARS-CoV-2 and other pandemic viruses. Aligos plans to advance its 3CLpro inhibitor, ALG-097558, into clinical trials, which has shown superior potency against COVID-19 variants compared to existing treatments. The collaboration includes experts from top universities and pharmaceutical companies to expedite drug development.

Aligos Therapeutics (Nasdaq: ALGS) announced that its Chairman and CEO, Lawrence M. Blatt, Ph.D., MBA, will present at the Jefferies Healthcare Conference on June 8, 2022, at 3:30 PM ET in New York City. The session will cover the company's efforts in developing therapies for viral and liver diseases.

Additionally, Aligos management will participate in investor 1x1 meetings during the conference. A replay of the presentation will be available for 90 days on Aligos' investor website.

Aligos Therapeutics (Nasdaq: ALGS) reported its Q1 2022 financial results, highlighting a net loss of $35.6 million, compared to $27.7 million in Q1 2021. Cash reserves totaled $183.2 million as of March 31, 2022, down from $205.8 million at the end of 2021, but sufficient to fund operations until mid-2024. Despite terminating its STOPS™ and ASO HBV programs due to poor results, Aligos is advancing its pipeline with multiple candidates, including ALG-000184 for HBV and ALG-097558, a coronavirus inhibitor, expected to file for clinical trials in H2 2022.

Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced the presentation of three posters on its chronic hepatitis B (CHB) portfolio at the International Liver Congress 2022 in London from June 22-26, 2022. The posters will cover the safety and efficacy of the class II capsid assembly modulator ALG-000184, the HBV siRNA ALG-125755, and oral PDL1 inhibitors for CHB treatment. These presentations aim to advance Aligos’ diverse CHB portfolio, potentially improving outcomes for patients. The company is committed to developing targeted therapies for viral infections and liver diseases.

Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced plans to report its first quarter 2022 financial results on May 4, 2022, after U.S. market close. The company focuses on developing innovative therapeutics for viral and liver diseases, including chronic hepatitis B and nonalcoholic steatohepatitis (NASH). Established in 2018, Aligos aims to leverage its expertise in drug development to advance its therapeutic pipeline.

Forward-looking statements in the release highlight potential risks in drug development and market conditions.