Welcome to our dedicated page for Aligos Therapeutics news (Ticker: ALGS), a resource for investors and traders seeking the latest updates and insights on Aligos Therapeutics stock.
Aligos Therapeutics, Inc. (NASDAQ: ALGS) is a clinical stage biotechnology company focused on therapies for liver and viral diseases, and its news flow reflects progress across this pipeline. Company announcements frequently highlight developments in chronic hepatitis B virus (HBV) programs, obesity and metabolic dysfunction-associated steatohepatitis (MASH) research, and broader corporate activities.
News items include updates on pevifoscorvir sodium, an oral capsid assembly modulator (CAM-E) under investigation for chronic HBV infection. Aligos issues press releases on clinical trial milestones, such as the initiation and enrollment of the Phase 2 B-SUPREME study, as well as data presentations at major scientific meetings. These communications describe antiviral activity, biomarker changes, and study designs that are central to understanding the company’s HBV strategy.
Investors and observers can also find coverage of ALG-055009, a THR-β agonist being studied for obesity and MASH. News from Aligos has detailed nonclinical in vivo results in diet-induced obese mouse models, showing synergistic body weight and fat mass loss when ALG-055009 is combined with incretin receptor agonists such as semaglutide or tirzepatide. Such updates provide insight into how the company positions this candidate within emerging combination approaches in cardiometabolic disease.
Beyond pipeline data, the ALGS news stream includes corporate and financial disclosures such as quarterly business updates, financial results, inducement grants under Nasdaq Listing Rule 5635(c)(4), amendments to equity plans, and senior leadership appointments. The company also announces participation in healthcare and investor conferences, where members of management discuss strategy and development programs.
By following ALGS news, readers can track clinical progress, preclinical findings, capital and governance actions, and organizational developments that shape Aligos Therapeutics’ efforts in liver and viral disease therapeutics.
Aligos Therapeutics (Nasdaq: ALGS) is set to present five scientific abstracts at the EASL Digital International Liver Congress™ 2021 from June 23-26, 2021. The presentations will showcase their progress on chronic hepatitis B (CHB) treatments, including two candidates in Phase 1b studies. Both the STOPS™ molecule and CAPSID Assembly Modulator (CAM) are being evaluated in CHB patients, with preliminary data expected by H2 2021. Additionally, ASO and siRNA candidates are on track for clinical development in H2 2021 and H1 2022, respectively.
Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced promising results from its study on ALG-000184, presented at the HBV-TAG 2021 Conference. Subjects receiving 100 mg of ALG-000184 for 14 days showed a mean reduction of 2.9 log10 IU/mL in HBV DNA levels. Notably, 50% of subjects had HBV DNA below the lower limit of quantitation. The drug was well tolerated and demonstrated significant antiviral activity. Aligos plans to share more data later this year and continue developing its CHB programs.
Aligos Therapeutics, a clinical stage biopharmaceutical company, announced that its CEO, Lawrence Blatt, will present at the Jefferies Virtual Healthcare Conference on June 3, 2021, from 2:00 to 2:25 PM ET. The presentation will include a virtual Q&A session. Interested parties can access the event via a webcast. The conference will feature over 400 companies and 3,000 investors discussing healthcare trends and investment opportunities.
Aligos Therapeutics reported its Q1 2021 financial results, revealing a net loss of $27.7 million or $0.74 per share, up from a loss of $20.0 million or $7.56 per share in Q1 2020. R&D expenses increased to $22.9 million, driven by clinical trials for drug candidates ALG-010133 and ALG-000184. General and administrative expenses rose to $5.8 million. Cash reserves decreased from $243.5 million at the end of 2020 to $213.4 million. Despite pandemic challenges, Aligos remains on track with its clinical programs, aiming to commence trials for several candidates in the coming months.
Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced it will release its first quarter 2021 financial results on May 10, 2021, after market close. The company focuses on developing novel therapeutics for viral and liver diseases, particularly chronic hepatitis B and nonalcoholic steatohepatitis. Founded in 2018, Aligos aims to leverage its team's extensive drug development experience to advance its pipeline of targeted antiviral therapies.
Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced the appointment of James Scopa, J.D., MBA, to its board of directors on April 27, 2021. CEO Lawrence Blatt stated this addition supports Aligos' growth as it transitions towards mid-stage clinical trials for chronic hepatitis B. Scopa brings over 30 years of life sciences experience as an investor and advisor, positioning him to provide strategic guidance. He has previously held significant roles at MPM Capital and Deutsche Banc Alex. Brown, enhancing Aligos' leadership as it expands in viral and liver disease therapies.
Aligos Therapeutics has commenced patient dosing in its ongoing study of ALG-000184, a drug candidate targeting chronic hepatitis B (CHB). This study evaluates ALG-000184's ability to inhibit viral replication by measuring HBV DNA and RNA levels. The company aims to combine ALG-000184 with other therapies to achieve better treatment outcomes. Preliminary data from previous trials indicate a favorable safety profile. Initial data on safety and antiviral activity are expected in the second half of 2021, contributing to Aligos' goal of improving CHB treatment regimens.
Aligos Therapeutics (NASDAQ: ALGS) reported strong financial results for Q4 and the full year 2020, with cash reserves of $243.5 million following a successful IPO raising $167.2 million. The company advanced two drug candidates, ALG-010133 and ALG-000184, into clinical trials for Chronic Hepatitis B (CHB) and expects to generate safety and antiviral activity data in 2021. However, net losses reached $108.5 million for the year, up from $52.3 million in 2019, reflecting increased R&D expenses of $79.9 million.
Aligos Therapeutics (Nasdaq: ALGS) has initiated dosing of its first drug candidate, ALG-010133, in chronic hepatitis B (CHB) patients as part of the ALG-010133-101 study. This proprietary molecule aims to reduce viral S-antigen levels, pivotal for HBV replication. Preclinical studies show promising inhibition of S-antigen. Currently, 72 healthy volunteers have been dosed, indicating an acceptable safety profile. Results from the initial patient cohorts are expected in the second half of 2021. Aligos aims to develop a treatment regimen that may lead to a functional cure for CHB.
Aligos Therapeutics (Nasdaq: ALGS) announced the presentation of its SARS-CoV-2 3CLpro inhibitor candidate, ALG-097111, at the 28th Conference on Retroviruses and Opportunistic Infections. The presentation highlighted in vivo evidence of potent virus inhibition in infected hamsters, achieving a 3.5 log10 reduction in viral RNA. ALG-097111 showed high selectivity with an IC50 of 7 nM, indicating its potential as a targeted therapeutic option amid COVID-19's evolving strains. CEO Lawrence Blatt emphasized its importance for untreated and vaccine-resistant patients.