Alkermes Plc Stock Price, News & Analysis

Alkermes plc (Nasdaq: ALKS) will present data on nemvaleukin alfa, an investigational immunotherapy, at the Society of Gynecologic Oncology 2022 Annual Meeting from March 18-21, 2022. The focus will be on outcomes from the ARTISTRY-1 study in platinum-resistant ovarian cancer patients, with a plenary oral presentation scheduled for March 19. Additionally, a poster on the ongoing ARTISTRY-7 study will be presented, comparing nemvaleukin plus pembrolizumab against chemotherapy. These studies aim to evaluate the safety and effectiveness of nemvaleukin in cancer treatment.

On February 17, 2022, Alkermes plc (Nasdaq: ALKS) presented new findings from the ARTISTRY-1 clinical trial of nemvaleukin alfa at the ASCO GU Cancers Symposium. The data demonstrate significant anti-tumor activity in patients with advanced renal cell carcinoma (RCC) treated with nemvaleukin as a monotherapy, particularly in those previously treated with checkpoint inhibitors. Key findings include a 60% reduction in target lesions for some patients and a notable immune response. Safety data align with previous reports, showing manageable adverse events without treatment-related deaths.

Alkermes plc (Nasdaq: ALKS) reported financial results for the quarter and year ended Dec. 31, 2021, showing total revenues of $324.5 million for Q4 2021 and $1.17 billion for the year, reflecting a year-over-year increase. Net income for Q4 was $0.9 million, a significant turnaround from a net loss of $42.6 million in the same quarter of the previous year. However, the company anticipates a GAAP net loss of $180 to $210 million for 2022, primarily due to the expected loss of royalties from long-acting INVEGA products. Alkermes aims to drive long-term profitability and shareholder value creation.

Alkermes announces positive topline results from the ENLIGHTEN-Early phase 3b study of LYBALVI (olanzapine and samidorphan) in young adults (ages 16-39) with schizophrenia, schizophreniform disorder, or bipolar I disorder. The study met its primary endpoint, showing less weight gain in patients treated with LYBALVI (mean: 4.91%) compared to olanzapine (mean: 6.77%, p=0.012) at week 12. Secondary endpoints also favored LYBALVI in weight gain percentages and symptom severity. Safety profiles were consistent with prior studies, with a majority of patients completing the trial.

Alkermes plc (Nasdaq: ALKS) will conduct a conference call on February 16, 2022, at 8:00 a.m. ET to discuss its fourth quarter and year-end 2021 financial results. The call will provide insights into the company's financial expectations for 2022 and include an operational update. Investors can access the webcast and slides via the Investors section on Alkermes' website. Dial-in details for U.S. and international callers are provided. A replay will be available shortly after the event.

Alkermes plc (Nasdaq: ALKS) announced its presentation of clinical data on nemvaleukin alfa, an investigational IL-2 variant immunotherapy, at the ASCO Gastrointestinal Cancers Symposium from Jan. 20-22, 2022. The poster will feature findings from the ARTISTRY-1 phase 1/2 study, evaluating nemvaleukin's efficacy and tolerability alone and with KEYTRUDA in advanced GI cancers. The abstract number is 659, presented by Dr. Ulka N. Vaishampayan. Nemvaleukin aims to enhance tumor-killing immune cells while minimizing immunosuppression.

Alkermes plc (Nasdaq: ALKS) will present a corporate overview at the 40th Annual J.P. Morgan Healthcare Conference on January 12, 2022, at 11:15 a.m. EST. CEO Richard Pops will lead the presentation, followed by a Q&A session. The event will be accessible via live webcast on the company's investor relations page and archived for 14 days. Alkermes is focused on developing innovative medicines in neuroscience and oncology, with a portfolio aimed at addiction, schizophrenia, and bipolar I disorder.

Alkermes plc (Nasdaq: ALKS) announced its participation in the fourth annual Evercore ISI HealthCONx Conference on December 2, 2021, at 10:30 a.m. ET. The event will be accessible under the Investors section of Alkermes' website and archived for 14 days. Alkermes is a global biopharmaceutical company focused on developing innovative medicines in neuroscience and oncology, with a pipeline targeting neurodegenerative disorders and cancer.