Alkermes Plc Stock Price, News & Analysis

Alkermes (ALKS) has launched Vibrance-3, a Phase 2 clinical study evaluating ALKS 2680 for idiopathic hypersomnia (IH). The study will assess the safety and efficacy of their novel oral selective orexin 2 receptor agonist versus placebo in adults with IH.

The randomized, double-blind trial will enroll approximately 96 patients across U.S., Australia, and Europe sites. Participants will receive one of three doses (10mg, 14mg, or 18mg) or placebo once-daily for eight weeks. The primary endpoint measures decrease in sleepiness using the Epworth Sleepiness Scale score.

This development follows encouraging Phase 1b data and addresses a significant unmet need, as over 90% of patients in a recent Sleep Consortium survey reported moderate to high impact of IH symptoms on their lives. IH affects an estimated 40,000 people in America.

A new national survey conducted by The Harris Poll for Alkermes (ALKS) reveals critical insights into healthcare providers' perspectives on treating schizophrenia and bipolar I disorder (BDI). The September 2024 survey, involving over 250 healthcare providers, highlights that 98% of respondents consider patient quality of life equally important as symptom management.

Key findings show that medication adherence is a primary concern, with patients switching medications frequently - BDI patients average seven switches and schizophrenia patients eight switches in their lifetime. About 66% of providers reported good/excellent quality of life for BDI patients, compared to only 21% for schizophrenia patients.

The survey revealed that providers prioritize symptom management (98% for BDI, 97% for schizophrenia) and quality of life improvements (96% for BDI, 94% for schizophrenia) when considering treatment efficacy. Common treatment challenges include medication effectiveness (82%) and side effects (81%). Most providers (97%) seek options to minimize the number of different treatments patients need to take.

Alkermes plc (Nasdaq: ALKS) has announced its participation in two major upcoming investor conferences in March 2025. The company will engage in webcast fireside chats at the TD Cowen 45th Annual Health Care Conference on March 5 at 9:50 a.m. ET and the Leerink Partners Global Healthcare Conference 2025 on March 12 at 11:20 a.m. ET.

The webcasts will be accessible through the Investors tab on Alkermes' website and will remain archived for 14 days. Alkermes is a global biopharmaceutical company focused on neuroscience, with a portfolio including treatments for alcohol dependence, opioid dependence, schizophrenia, and bipolar I disorder. The company maintains operations across Ireland, Massachusetts, and Ohio.

Alkermes (ALKS) reported strong financial results for Q4 and full-year 2024, with total revenues of $1.56 billion. The company achieved 18% year-over-year growth in proprietary product net sales, reaching over $1 billion. Key highlights include:

- GAAP Net Income from continuing operations of $372.1 million ($2.20 per share)
- Total proprietary net sales reached $1.08 billion
- Year-end cash position of $824.8 million
- Company became debt-free after retiring $290 million in debt

For 2025, Alkermes provided financial guidance including:
- Total revenue expectations of $1.34-1.43 billion
- GAAP Net Income of $175-205 million
- EBITDA guidance of $215-245 million

The company is advancing its neuroscience pipeline, with ALKS 2680 Phase 2 studies in narcolepsy ongoing and data expected in H2 2025.

Alkermes (ALKS) has announced it will host a conference call and webcast on February 12, 2025, at 8:00 a.m. ET to discuss its fourth quarter and year-end 2024 financial results. During the presentation, management will also outline financial expectations for 2025 and provide a company update.

The event will be accessible through the company's website investor section, with a conference call available at +1 877 407 2988 for U.S. callers and +1 201 389 0923 for international participants. A replay will be available approximately two hours after the event.

Alkermes is a global biopharmaceutical company focused on neuroscience, with commercial products targeting alcohol dependence, opioid dependence, schizophrenia, and bipolar I disorder. The company maintains operations in Ireland, Massachusetts, and Ohio.

Alkermes plc (Nasdaq: ALKS) has announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference. CEO Richard Pops will deliver a corporate overview and update on Wednesday, Jan. 15, 2025, at 11:15 a.m. PST, followed by a Q&A session. The presentation will be accessible via webcast on the company's website under the Investors tab and will remain archived for 14 days.

Alkermes is a global biopharmaceutical company focused on neuroscience innovation. Their portfolio includes commercial products treating alcohol dependence, opioid dependence, schizophrenia, and bipolar I disorder. The company's pipeline features clinical and preclinical candidates for neurological disorders, including narcolepsy and idiopathic hypersomnia. Based in Ireland, Alkermes maintains a corporate office and R&D center in Massachusetts and a manufacturing facility in Ohio.

Alkermes plc (Nasdaq: ALKS) has announced its participation in two major investor conferences in December 2024. The company will present at the 7th Annual Evercore ISI HealthCONx Conference on December 3 at 10:25 a.m. ET and the Piper Sandler 36th Annual Healthcare Conference on December 4 at 4:00 p.m. ET.

The presentations will be accessible via live webcasts on the company's website under the Investors tab and will remain archived for 14 days. Alkermes is a global biopharmaceutical company focused on neuroscience, with commercial products for alcohol dependence, opioid dependence, schizophrenia, and bipolar I disorder. The company maintains operations in Ireland, Massachusetts, and Ohio.

Alkermes plc (Nasdaq: ALKS) has announced its participation in two upcoming investor conferences in November 2024. The company will present at the Stifel Healthcare Conference on November 18 at 8:35 a.m. ET and the Jefferies London Healthcare Conference on November 19 at 8:00 a.m. ET. Live webcasts will be available on Alkermes' website under the Investors tab and archived for 14 days.

Alkermes is a global biopharmaceutical company focused on neuroscience, with commercial products for alcohol dependence, opioid dependence, schizophrenia, and bipolar I disorder. The company maintains operations in Ireland, Massachusetts, and Ohio.

Alkermes announced presentations at two key scientific conferences, showcasing research on LYBALVI® (olanzapine and samidorphan), ARISTADA® (aripiprazole lauroxil), and ALKS 2680. At the 37th Annual Psych Congress and the 2024 Neuroscience Education Institute Congress, Alkermes presented 12 posters, including a study on healthcare resource utilization in patients with schizophrenia and bipolar I disorder after LYBALVI initiation. The study revealed significant reductions in inpatient admissions and emergency department visits. Limitations include potential data omissions and coding errors. Additionally, safety and efficacy data from a phase 1b study of ALKS 2680 in narcolepsy were presented.