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Alamar Biosciences Launches NULISAseq™ Immune 340 Panel for Comprehensive Profiling of the Immune Proteome

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Alamar Biosciences (Nasdaq: ALMR) launched the NULISAseq Immune 340 Panel, its broadest multiplexed immune profiling solution for translational research and drug development. The assay measures about 340 immune-related proteins from a single sample, expanding on the earlier NULISAseq Inflammation Panel 250.

According to Alamar Biosciences, the panel’s ultra-sensitive technology detects low-abundance cytokines, chemokines, checkpoint regulators, and cell death markers at fg/mL to sub-pg/mL levels, supporting research in cancer, cardiovascular and metabolic diseases, autoimmune diseases, and aging, including “inflammaging.” A Sanofi biomarker lead highlighted its combined breadth and sensitivity for immune landscape profiling.

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Market Context

ALMR’s prior product launch was followed by a -1.68% 24-hour reaction. That history adds context to ...
Analysis

ALMR’s prior product launch was followed by a -1.68% 24-hour reaction. That history adds context to this panel announcement, while low short positioning is a less prominent risk factor; adoption evidence and financial contribution remain areas to watch.

Key Figures

Immune proteins measured: approximately 340 immune-related proteins Prior panel designation: 250 Low concentration range: fg/mL to sub-pg/mL +1 more
4 metrics
Immune proteins measured approximately 340 immune-related proteins NULISAseq Immune 340 Panel
Prior panel designation 250 NULISAseq Inflammation Panel 250
Low concentration range fg/mL to sub-pg/mL concentrations of immune mediators
Announcement date July 28, 2026 Alamar Biosciences announcement

Historical Context

5 past events · Latest: Jul 14 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jul 14 earnings date notice Neutral -3.4% Company scheduled second-quarter 2026 results for August 10 after market close.
Jul 13 partnership initiative Positive -3.6% National initiative planned profiling about 21,000 plasma samples from 10,000 participants.
Jul 10 conference presentation Positive +7.3% NULISA data appeared in more than 140 AAIC 2026 presentations.
Jul 07 product launch Positive -1.7% Company launched commercial eMTBR-Tau blood immunoassay within NULISAseq Neuro 220.
May 08 earnings report Positive +1.3% First-quarter revenue reached $26.0 million, up 99% year-over-year.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

ALMR's positive product and partnership announcements produced mixed reactions, including -3.59% and -1.68% moves, while one conference-related event gained 7.33%.

Key Terms

immune proteome, cytokines, chemokines, inflammaging, +1 more
5 terms
immune proteome medical
"Expanded panel advances the understanding of immune system"
The immune proteome is the complete set of proteins produced by and interacting with the immune system, including antibodies, cytokines, receptors and other signaling or structural molecules involved in immune responses. Investors care because changes in this protein “inventory” can reveal disease signals, drug targets, or diagnostic biomarkers—similar to how a fingerprint or snapshot of activity helps detect problems and measure the effect of therapies or vaccines.
cytokines medical
"measuring the cytokines and other biomarkers of immune activation"
Small proteins produced by immune and other cells that act as on/off signals or “text messages,” telling cells to ramp up, calm down, grow, or move during infection, injury, or disease. Investors watch cytokines because they are common drug targets and biomarkers—changes in cytokine activity can make a therapy work, cause serious side effects, or determine clinical trial and regulatory outcomes, all of which affect a company’s value.
chemokines medical
"including cytokines, chemokines, and cell death pathway markers"
Small signaling proteins that act like traffic signals, guiding immune and inflammatory cells to specific locations in the body such as sites of infection, injury or disease. They matter to investors because chemokines are common drug targets and biomarkers: changes in their activity can drive therapeutic strategies, affect clinical trial design and outcomes, and influence regulatory decisions and commercial potential for treatments in immunology, oncology and other fields.
inflammaging medical
"This is especially true of inflammaging, the chronic, low-grade inflammation"
Chronic, low-level inflammation that builds up as people age and slowly damages tissues and organs, like a smoldering fire that eventually weakens a house. It matters to investors because this underlying process is linked to many age-related diseases (heart disease, dementia, diabetes), creating large markets for diagnostics, drugs and preventive treatments and influencing healthcare costs, regulatory priorities and long-term company valuations.
immunoassays technical
"well below the floor of conventional immunoassays"
Immunoassays are laboratory tests that use specially made immune proteins (antibodies) to find and measure specific molecules—like proteins, hormones or bits of a virus—in blood or other samples, similar to using a highly specific key to pick out one lock in a crowded room. Investors care because these tests drive sales of diagnostic devices and consumables, affect clinical trial and regulatory outcomes, and can create recurring revenue and competitive advantage for medical and biotech companies.

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Expanded panel advances the understanding of immune system across translational and clinical research in cancer, cardiovascular and metabolic diseases, autoimmune diseases and aging 

Highly sensitive multiplex measurement captures regulatory proteins, like checkpoint inhibitors, and low abundance targets that standard platforms routinely miss

FREMONT, Calif., July 28, 2026 (GLOBE NEWSWIRE) -- Alamar Biosciences, Inc. (Nasdaq: ALMR), a leader in precision proteomics dedicated to advancing the early detection of disease, today announced the launch of the NULISAseq™ Immune 340 Panel, its broadest multiplexed immune profiling solution available for translational research and drug development. The panel expands on the NULISAseq Inflammation Panel 250, to deliver simultaneous measurement of approximately 340 immune-related proteins from a single sample. By measuring key proteins that were previously undetectable by other methods, the Immune 340 Panel deepens the understanding of the immune proteome in critical disease areas across cancer, cardiovascular and metabolic diseases, autoimmune diseases, and aging research.

“The immune system holds some of the earliest and most informative signals of disease, yet much of that biology has been out of reach,” said Dr. Yuling Luo, founder, chief executive officer and chair of Alamar. “NULISAseq Immune 340 gives researchers an unprecedented view of immune activity. We believe that this view will accelerate biomarker discovery, strengthen the development of new therapies and diagnostics, and advance our mission of detecting disease earlier and helping people stay healthier for longer.”

Immune responses are never driven by a single protein. Pathway crosstalk, feedback loops, and cell type cooperation all demand multi-protein context to interpret. Understanding this biology, and catching it early, requires measuring the cytokines and other biomarkers of immune activation that signal disease before symptoms appear. The challenge is detection. Many immune mediators, including cytokines, chemokines, and cell death pathway markers, circulate at fg/mL to sub-pg/mL concentrations, well below the floor of conventional immunoassays. This is especially true of inflammaging, the chronic, low-grade inflammation that builds quietly with age as immune senescence and neuroimmune activation compound to drive cardiovascular, metabolic, neurodegenerative, and cancer risk. Its key signals have largely been invisible to researchers until now.

In drug development, the ability to simultaneously profile the full immune landscape – not just the well-characterized cytokines, but the entire network of checkpoints, metabolic regulators, cell death mediators, and co-stimulatory signals – fundamentally changes what we can learn from a single sample,” said Bailin Zhang, PhD, head of exploratory biomarkers in the Translational Medicine Unit at Sanofi. “What makes the NULISAseq Immune 340 Panel distinctive is the combination of breadth and sensitivity. Many of the proteins most relevant to immune mechanisms of action, resistance, and toxicity have historically been undetectable in blood. Having access to them, alongside the canonical markers, in one multiplexed run opens new possibilities for biomarker discovery and patient stratification.”

For more information about the NULISAseq Immune 340 Panel and Alamar's full portfolio of precision proteomics solutions, visit alamarbio.com.

About Alamar Biosciences

Alamar is a commercial-stage proteomics company establishing a gold standard in protein detection and analysis. Leveraging our proprietary NULISA™ technology and the ARGO™ HT System, our platform is designed to detect protein biomarkers at extremely low concentrations in blood with ultra-high sensitivity, high specificity, flexible multiplexing, broad dynamic range and seamless automation. We refer to this combination of features as “Precision Proteomics,” and believe it fills a critical gap in the field of advanced proteomics, helping researchers unlock the full spectrum of protein biomarkers across disease states. Learn more at alamarbio.com.

Forward-Looking Statements

This press release may contain forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as "aims," "anticipates," "believes," "could," "estimates," "expects," "forecasts," "intends," "may," "plans," "possible," "potential," "seeks," "will" and variations of these words or similar expressions that are intended to identify forward-looking statements. Any such statements in this press release that are not statements of historical fact may be deemed to be forward-looking statements. These forward-looking statements include, without limitation, statements regarding the capabilities, performance, and impact of the NULISAseq™ Immune 340 Panel, including the anticipated benefits of the panel for research and drug development. Any forward-looking statements in this press release are based on Alamar Biosciences’ current expectations and involve assumptions that may never materialize or may prove to be incorrect. Readers are cautioned that actual results could differ materially from those expressed or implied in Alamar Biosciences’ forward-looking statements due to a variety of risks and uncertainties, which include, without limitation, risks and uncertainties related to intense competition in the proteomics market, exposure to legal proceedings, regulatory inquiries and other legal matters, failure to develop new assays or instruments, dependence on researchers who rely heavily on government funding, reductions in spending by research and academic institutions, the potential for products to be subject to more onerous regulation by the FDA or other regulatory requirements, the complexity of manufacturing Alamar Biosciences’ instruments and consumables, failure to obtain marketing authorizations for future products that are intended for clinical or diagnostic use, Alamar Biosciences’ ability to protect its intellectual property, and the other risks described in Alamar Biosciences’ filings with the U.S. Securities and Exchange Commission (SEC), including those described from time to time under the caption “Risk Factors” and elsewhere in Alamar Biosciences’ filings with the SEC, including its Quarterly Report on Form 10-Q filed with the SEC on May 8, 2026. Alamar Biosciences explicitly disclaims any obligation to update any forward-looking statements except to the extent required by law.

Media Contact: media@alamarbio.com

Investor Contact: investors@alamarbio.com


FAQ

What is Alamar Biosciences’ NULISAseq Immune 340 Panel launched in July 2026 (NASDAQ: ALMR)?

The NULISAseq Immune 340 Panel is Alamar Biosciences’ broadest multiplexed immune profiling assay, measuring about 340 immune-related proteins from one sample. According to Alamar Biosciences, it targets translational research and drug development across cancer, cardiovascular and metabolic diseases, autoimmune disorders, and aging research.

How many proteins does the NULISAseq Immune 340 Panel from Alamar Biosciences (ALMR) measure?

The NULISAseq Immune 340 Panel measures approximately 340 immune-related proteins in a single run. According to Alamar Biosciences, this expanded coverage builds on its Inflammation Panel 250 and aims to provide broader insight into immune mechanisms across multiple disease areas and research settings.

What makes Alamar Biosciences’ NULISAseq Immune 340 Panel different from standard immunoassay platforms?

The NULISAseq Immune 340 Panel is designed to detect proteins at fg/mL to sub-pg/mL concentrations, below conventional assay limits. According to Alamar Biosciences, this sensitivity enables measurement of low-abundance cytokines, chemokines, checkpoints, and cell death markers that are often missed by standard platforms.

Which disease areas can benefit from the NULISAseq Immune 340 Panel by Alamar Biosciences (NASDAQ: ALMR)?

The NULISAseq Immune 340 Panel is intended for research in cancer, cardiovascular and metabolic diseases, autoimmune diseases, and aging. According to Alamar Biosciences, it is particularly relevant for studying chronic low-grade inflammation, or inflammaging, and early immune signals of disease.

How could Alamar Biosciences’ NULISAseq Immune 340 Panel support biomarker discovery and drug development?

The NULISAseq Immune 340 Panel enables simultaneous profiling of diverse immune mediators from one sample, including checkpoints and co-stimulatory signals. According to Alamar Biosciences, this multiplexed, sensitive readout may help accelerate biomarker discovery, patient stratification, and understanding of therapeutic mechanisms and resistance.