Welcome to our dedicated page for Altimmune news (Ticker: ALT), a resource for investors and traders seeking the latest updates and insights on Altimmune stock.
Altimmune Inc (ALT) is a clinical-stage biopharmaceutical company pioneering peptide-based therapeutics for obesity, metabolic disorders, and liver diseases. This page serves as the definitive source for verified news and press releases directly from the company and trusted financial publications.
Investors and researchers will find timely updates on clinical trial progress, including developments for pemvidutide, the company’s GLP-1/glucagon dual receptor agonist candidate. Track regulatory milestones, partnership announcements, and strategic initiatives that shape Altimmune’s research pipeline.
Our curated news feed includes earnings reports, scientific presentations, and manufacturing updates, providing a holistic view of the company’s trajectory. All content is rigorously vetted to ensure alignment with financial reporting standards and clinical accuracy.
Bookmark this page for efficient access to Altimmune’s latest material events. Check regularly for updates on pivotal studies in metabolic-associated steatohepatitis (MASH) and obesity therapeutics, ensuring you stay informed on developments impacting this innovative biopharma leader.
Altimmune (NASDAQ: ALT) announced publication in The Lancet of 24-week IMPACT Phase 2b results for pemvidutide in MASH and a late-breaking oral presentation at AASLD The Liver Meeting® 2025 on Nov 11, 2025.
Key 24-week findings: MASH resolution occurred in 58% (1.2 mg) and 52% (1.8 mg) versus 20% for placebo; liver fat normalization reached 31% and 44% versus 4% for placebo; mean weight reductions were −4.8% and −5.8% versus −0.5% for placebo. Multiple non-invasive tests (MRI-PDFF, FibroScan, cT1, ELF, PRO-C3, FAST) showed consistent improvements and liver stiffness fell by −3.7 kPa and −2.2 kPa for active doses. Safety/tolerability were described as favorable with low discontinuation rates. Altimmune said longer-term NIT and weight-loss readouts will be provided in Q4 2025.
Altimmune (Nasdaq: ALT) reported AI-based digital pathology analysis from the IMPACT Phase 2b pemvidutide trial in MASH showing significant fibrosis reductions vs placebo at 24 weeks.
Key results: 31% of patients on pemvidutide 1.8 mg achieved ≥60% total fibrosis area reduction (n=85) vs 8% placebo (n=86; p=0.0003); early fibrosis ≥60% reduction: 34% (1.8 mg) vs 9% placebo (p<0.0001); advanced fibrosis ≥60% reduction: 27% (1.8 mg) vs 11% placebo (p=0.0063). Non-invasive tests including PRO-C3:CTX-III ratio and PRO-C6 also improved.
Altimmune (Nasdaq: ALT) reported Q3 2025 corporate and financial updates on November 6, 2025. Key points: $210.8M cash, cash equivalents and short-term investments as of September 30, 2025 (about +60% vs. Dec 31, 2024); net loss of $19.0M (−$0.21 per share) for Q3 2025; R&D expense of $15.0M in Q3 2025. Important clinical milestones: an End-of-Phase 2 meeting with FDA scheduled Q4 2025 for pemvidutide MASH and 48-week IMPACT data expected before year-end 2025. Corporate: amended Hercules facility to $125M with an additional $20M draw, and three senior hires (CMO, CCO, CLO).
Altimmune (Nasdaq: ALT) said company management will attend two investor conferences in November 2025: a Stifel 2025 Healthcare Conference fireside chat on November 12, 2025 at 10:00 a.m. ET, and a Jefferies Global Healthcare Conference fireside chat on November 20, 2025 at 9:30 a.m. GMT. Management will be available for one-on-one meetings. Both sessions will be webcast and accessible via the Events section of the company's website.
Altimmune (Nasdaq: ALT) announced early completion of enrollment in RECLAIM, a Phase 2 trial of pemvidutide in adults with alcohol use disorder (AUD). Approximately 100 patients were randomized 1:1 to 2.4 mg pemvidutide or placebo once weekly for 24 weeks. The primary endpoint is change in average number of heavy drinking days per week; key secondary endpoints include a 2-level WHO risk drinking reduction and change in PEth biomarker. Enrollment finished several months ahead of schedule and topline results are expected in 2026. Altimmune is also enrolling the RESTORE Phase 2 ALD trial and expects 48-week IMPACT results for MASH later this quarter.
Altimmune (Nasdaq: ALT) will report its third quarter 2025 financial results on Thursday, November 6, 2025. Management will host a conference call and webcast at 8:30 a.m. ET the same day to discuss results and provide a business update.
The live webcast will be available on Altimmune’s Investor Relations website and requires registration to receive dial-in numbers and a unique PIN. A replay of the call will be posted on the Investor Relations site and remain available for up to three months.
Altimmune (Nasdaq: ALT) will present 24-week Phase 2b IMPACT data for pemvidutide in metabolic dysfunction-associated steatohepatitis (MASH) at AASLD The Liver Meeting® 2025 in Washington, D.C., Nov 7–11, 2025.
Two late-breaking presentations are scheduled: an oral podium on Nov 11, 2025 at 11:45 a.m. ET by Dr. Mazen Noureddin covering the randomized, placebo-controlled trial (publication 5001), and a late-breaking poster on Nov 8, 2025 from 1:00–2:00 p.m. ET by Dr. Julio Gutierrez showing AI-based digital pathology analysis of liver fibrosis (publication 5025). The company expects to announce 48-week data in Q4 2025 and will post the presentation and poster on its Events page.
Altimmune (NASDAQ:ALT) has appointed Christophe Arbet-Engels, MD, PhD as Chief Medical Officer, effective October 1, 2025. Dr. Arbet-Engels brings over 30 years of experience and will lead the clinical development of pemvidutide, including the planned Phase 3 trial in metabolic dysfunction-associated steatohepatitis (MASH).
He succeeds Scott Harris, M.D., who will remain as Senior Strategic Advisor until February 2026. Dr. Arbet-Engels joins from X4 Pharmaceuticals, where he contributed to the successful approval of Xolremdi. His compensation package includes options to purchase 450,000 shares and 150,000 restricted stock units of Altimmune's common stock.
The appointment comes at a crucial time as Altimmune prepares for upcoming 48-week data from the IMPACT trial in MASH and ongoing Phase 2 trials in Alcohol Use Disorder and Alcohol-associated Liver Disease.Altimmune (NASDAQ:ALT), a late clinical-stage biopharmaceutical company focused on liver and cardiometabolic diseases, has announced its participation in two upcoming investor conferences. Management will present at the Stifel 2025 Virtual Cardiometabolic Forum on September 30, 2025, at 10:30 a.m. ET, and the H.C. Wainwright Liver Disease Virtual Conference on October 21, 2025, at 7:00 a.m. ET.
Both presentations will feature fireside chats and will be available via webcast through the Events section of Altimmune's website. The company's management team will also be available for one-on-one meetings with investors during these events.
Altimmune (NASDAQ:ALT) has appointed Linda M. Richardson as Chief Commercial Officer, effective September 16, 2025. Richardson brings over 30 years of experience in sales, marketing, and commercial development, with expertise in metabolic disease, hepatology, cardiovascular, and addiction medicine.
Richardson joins Altimmune as the company approaches Phase 3 development of pemvidutide in MASH. She previously served as Chief Commercial Officer at Intercept Pharmaceuticals until early 2024 and held senior positions at Chimerix, Sanofi, Reliant Pharmaceuticals, and GSK.
As part of her compensation package, Richardson will receive options to purchase 278,000 shares and 96,000 restricted stock units (RSUs), with a four-year vesting schedule.
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