Welcome to our dedicated page for Altimmune news (Ticker: ALT), a resource for investors and traders seeking the latest updates and insights on Altimmune stock.
Altimmune, Inc. (Nasdaq: ALT) generates a steady flow of news as a late clinical-stage biopharmaceutical company developing peptide-based therapeutics for liver, metabolic and cardiometabolic diseases. Most company updates center on its lead investigational medicine, pemvidutide, a balanced 1:1 glucagon/GLP-1 dual receptor agonist in development for metabolic dysfunction-associated steatohepatitis (MASH), alcohol use disorder (AUD), alcohol-associated liver disease (ALD) and obesity.
News coverage of ALT frequently highlights clinical trial milestones. Altimmune issues detailed press releases on the IMPACT Phase 2b trial in MASH, including 24-week and 48-week topline data, changes in non-invasive tests of fibrosis and hepatic inflammation, and AI-based digital pathology analyses of liver biopsies. Additional updates describe progress in the RECLAIM Phase 2 trial in AUD and the RESTORE Phase 2 trial in ALD, including enrollment status and expected timelines for topline results.
Investors and followers of ALT stock also see regulatory and scientific news, such as Fast Track designations for pemvidutide in MASH and AUD, Breakthrough Therapy Designation for MASH, and publication of IMPACT trial data in peer-reviewed journals. Presentations at major medical meetings, including late-breaking oral and poster sessions at The Liver Meeting hosted by the American Association for the Study of Liver Diseases (AASLD), are common subjects of company announcements.
Altimmune’s news flow further includes corporate and financial updates. These range from quarterly financial results and business updates to CEO succession plans, executive appointments, term loan amendments and at-the-market equity offering arrangements disclosed in SEC filings and companion press releases. For anyone tracking ALT, this news page brings together clinical, regulatory, scientific and corporate developments in one place, making it easier to follow how Altimmune’s programs and capital strategy evolve over time.
Altimmune, a clinical-stage biopharmaceutical company, presented data on its GLP-1/glucagon dual receptor agonist candidate, pemvidutide, at the American Diabetes Association’s 84th Annual Scientific Sessions. Pemvidutide showed significant reductions in pro-inflammatory serum lipids, including total cholesterol, LDL-C, and triglycerides, by 28%, 26%, and 38% respectively. These lipid reductions were not linked to weight loss, implying a direct impact on lipid metabolism. The Phase 1 study involved 34 subjects receiving varying doses of pemvidutide or placebo for 12 weeks. Additionally, reductions in GlycA and GlycB, markers of systemic inflammation, and decreases in systolic and diastolic blood pressure were noted, suggesting a potential lowered cardiovascular disease risk.
Altimmune, a clinical-stage biopharmaceutical company listed on Nasdaq under the symbol ALT, will participate in the Piper Sandler 2nd Annual Virtual Obesity Investor Day on June 26, 2024. Company leaders, including CEO Vipin Garg, Ph.D., and Chief Scientific Officer Scott Roberts, Ph.D., will discuss insights from the American Diabetes Association's Scientific Sessions during a fireside chat at 9:30 a.m. EDT. The session will be webcast and accessible via the Events section of the Altimmune website.
Altimmune (Nasdaq: ALT), a clinical-stage biopharmaceutical company, will present data on their investigational drug, pemvidutide, at the American Diabetes Association’s (ADA) 84th Scientific Sessions from June 21-24, 2024, in Orlando, FL.
Pemvidutide, a GLP-1/glucagon dual receptor agonist, is being developed for obesity and NASH treatment. Two key presentations include:
- Dr. John J. Suschak discussing the effects of pemvidutide on cardioinflammatory lipids on June 22 at 4:45 PM EDT.
- Dr. Louis Aronne presenting 48-week Phase 2 trial data on June 23 at 1:45 PM EDT, also featured in ADA's Press Program.
Details will be available on Altimmune's website.
Altimmune presented new data at the EASL International Liver Congress 2024 highlighting the potential of pemvidutide in treating Metabolic Dysfunction-Associated Steatohepatitis (MASH). The data from Phase 1 trials indicate significant improvements in non-invasive tests, suggesting potential histologic benefits by Q1 2025. The trials show that pemvidutide's dual GLP-1/glucagon agonism could outperform GLP-1 alone in resolving MASH and reducing fibrosis. Additionally, lipidomic profiling supports its potential in addressing MASH-related co-morbidities like cardiovascular disease. Pemvidutide is currently being evaluated in a Phase 2b trial.
On May 29, 2024, Altimmune (Nasdaq: ALT), a clinical-stage biopharmaceutical company, announced its participation in two upcoming investor conferences. The company management will attend the Jefferies Global Healthcare Conference in New York on June 5, 2024, with a fireside chat at 2:00 p.m. ET. They will also attend the Goldman Sachs Global Healthcare Conference in Miami Beach on June 12, 2024, with a fireside chat at 9:20 a.m. ET. Both sessions will be webcast and accessible via the Events section of Altimmune's website.
Altimmune, a clinical-stage biopharmaceutical company, announced new data on pemvidutide, a novel peptide-based GLP-1/glucagon dual receptor agonist, at the EASL International Liver Congress™ 2024 in Milan. Pemvidutide is under development for treating obesity and metabolic dysfunction-associated steatohepatitis (MASH). The data highlights its anti-inflammatory and anti-fibrotic properties in subjects with metabolic dysfunction-associated steatotic liver disease (MASLD). Presentations include:
- Dr. Sarah Browne on metabolic dysfunction-associated steatohepatitis activity and fibrosis.
- Dr. Scot Roberts on plasma lipidomic profiling in subjects with obesity.
- Dr. Shaheen Tomah on noninvasive tests indicating histologic response in MASLD subjects.
These presentations will occur on June 5, 2024, at 8:30 am CEST, with posters displayed throughout the congress.
Roundhill Investments has launched the Roundhill GLP-1 & Weight Loss ETF (OZEM), now trading on Nasdaq. OZEM targets the growing market of GLP-1 receptor agonists and weight management drugs, which is projected to hit $100 billion by 2030. The ETF offers exposure to companies leading in obesity treatment innovation, including Eli Lilly, Novo Nordisk, and Innovent Biologics. CEO Dave Mazza emphasizes the substantial growth potential due to the rising global obesity rates. Key holdings in the ETF feature major pharmaceutical companies with a focus on weight loss therapeutics.
Altimmune announced its financial results for the first quarter of 2024, revealing cash, cash equivalents, and short-term investments of $182.1 million as of March 31, 2024. The company highlighted the ongoing IMPACT Phase 2b trial of pemvidutide in MASH, with top-line results expected in Q1 2025. Altimmune also emphasized the upcoming End-of-Phase 2 meeting with the FDA and the positive data from the Phase 2 MOMENTUM trial of pemvidutide in obesity. The company continues to advance enrollment in the IMPACT trial, with topline data anticipated in Q1 2025.
Altimmune, Inc. (Nasdaq: ALT) will participate in two upcoming investor conferences, the JMP Life Sciences Conference in New York on May 14, 2024, and the UBS Obesity Therapeutics Day virtual conference on May 23, 2024. The company's management team will be available for 1x1 meetings and will hold Fireside Chats at specific times. The sessions will be webcast on the Altimmune website.
Altimmune, Inc. (Nasdaq: ALT) will report its first quarter 2024 financial results and provide a business update on May 9, 2024. Altimmune management will host a conference call to discuss the financial results and business update.