ALX Oncology Announces Two Evorpacept Clinical Abstracts Accepted for Presentation at the AACR Annual Meeting

Rhea-AI Summary

ALX Oncology Holdings Inc. announces acceptance of two clinical abstracts for presentation at the AACR Annual Meeting. The abstracts focus on trials in patients with relapsed/refractory B-cell non-Hodgkin lymphoma and higher-risk myelodysplastic syndrome.

- Investigator-initiated trial in patients with relapsed or refractory B-cell non-Hodgkin lymphoma selected for oral presentation

SOUTH SAN FRANCISCO, Calif., March 05, 2024 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), an immuno-oncology company developing therapies that block the CD47 immune checkpoint pathway, today announced that two clinical abstracts have been accepted for presentation at the American Association for Cancer Research (“AACR”) Annual Meeting, which will be held in San Diego from April 5-10, 2024.

Session titles and information for the two abstracts are listed below and are now available on the AACR online program planner.

A Phase 1 investigator-initiated trial of evorpacept (ALX148), lenalidomide and rituximab for patients with relapsed or refractory B-cell non-Hodgkin lymphoma
Session Title: Clinical Trials Minisymposium (Oral Presentation) / Novel Agents and Emerging Therapeutic Strategies
Session Date and Time: Tuesday, April 9, 2024 2:30 PM – 4:30 PM PT
Abstract: CT037

Phase 1 study of azacitidine in combination with evorpacept for higher-risk myelodysplastic syndrome (MDS)
Session Title: Phase I Clinical Trials 1
Session Date and Time: Monday April 8, 2024 9:00 AM – 12:30 PM PT
Location: Poster Section 48
Poster Board Number: 10
Abstract: CT060

Copies of the presentations will be available on ALX Oncology’s website at https://alxoncology.com/science/#publications following presentation at the meeting.

About ALX Oncology

ALX Oncology is a publicly traded, clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 immune checkpoint inhibitor and bridge the innate and adaptive immune system. ALX Oncology’s lead product candidate, evorpacept, is a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. To date, evorpacept has been dosed in over 500 subjects and has demonstrated promising activity and favorable tolerability profile across a range of hematologic and solid malignancies in combination with various leading anti-cancer antibodies. ALX Oncology is currently focusing on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors.

What is the focus of the clinical abstracts accepted by ALX Oncology for presentation at the AACR Annual Meeting?

The abstracts focus on trials in patients with relapsed/refractory B-cell non-Hodgkin lymphoma and higher-risk myelodysplastic syndrome.

When and where will the AACR Annual Meeting be held?

The AACR Annual Meeting will be held in San Diego from April 5-10, 2024.

What is the Session Title for the Phase 1 investigator-initiated trial of evorpacept, lenalidomide, and rituximab?

The Session Title is Clinical Trials Minisymposium (Oral Presentation) / Novel Agents and Emerging Therapeutic Strategies.

Where can copies of the presentations be found after the meeting?

Copies of the presentations will be available on ALX Oncology's website at https://alxoncology.com/science/#publications.