Amgen Inc Stock Price, News & Analysis

Amgen (NASDAQ:AMGN) has declared a $1.76 per share dividend for Q1 2021, to be paid on March 8, 2021, to stockholders of record by February 15, 2021. This marks a 10% increase from the prior four quarters. The company continues its commitment to innovative therapeutics, addressing serious illnesses, and focusing on high unmet medical needs. Investors can view additional information on Amgen's offerings via their official site.

Amgen has submitted a New Drug Application (NDA) for sotorasib, a KRAS^G12C inhibitor, to the FDA for treating advanced non-small cell lung cancer (NSCLC). Sotorasib shows promise as the first approved targeted therapy for KRAS G12C mutation, found in about 13% of NSCLC patients. The NDA is supported by positive Phase 2 data from the CodeBreaK 100 study, demonstrating durable anticancer activity. The FDA will review the application under the Real-Time Oncology Review program, aiming for expedited access to effective treatments.

Amgen announced that the FDA granted Breakthrough Therapy designation for its investigational KRAS^G12C inhibitor, sotorasib, aimed at treating patients with advanced non-small cell lung cancer (NSCLC) with the KRAS G12C mutation. This designation underscores the unmet clinical need in a patient population lacking targeted therapies. Sotorasib is being tested in the CodeBreaK clinical program across 13 tumor types, with positive Phase 2 results indicating durable anticancer activity. Amgen plans to submit a new drug application by year-end 2020.

Amgen (NASDAQ:AMGN) has partnered with Karamo Brown to launch the Know Migraine Mission, aimed at increasing awareness and understanding of migraine. Karamo, who has suffered from migraines since high school, will share his experiences and encourage open conversations about the condition. Aimovig®, co-marketed with Novartis, is the first FDA-approved treatment for migraine prevention. The initiative focuses on combating stigma and promoting the significance of discussing migraine challenges, highlighting Aimovig's proven efficacy in reducing monthly migraine days.

Amgen announced its first presentation of clinical data for AMG 701, a half-life extended bispecific T cell engager, at the ASH Annual Meeting. Targeting BCMA, this immuno-oncology therapy was evaluated in 85 heavily pre-treated patients with relapsed/refractory multiple myeloma. The study revealed a 36% response rate, with some patients experiencing responses lasting up to 26 months. Adverse events included anemia (42%) and cytokine release syndrome (65%). This data emphasizes Amgen's commitment to innovative cancer treatments and the potential of the BiTE platform in addressing unmet medical needs.

Amgen and McKesson have established a multi-year strategic partnership aimed at enhancing cancer care in community oncology settings. With 1 in 5 cancer patients receiving an Amgen treatment and McKesson reaching 20% of U.S. cancer patients, this collaboration intends to optimize access to innovative therapies. The partnership will focus on improving molecular testing, treatment patterns, and utilizing real-world data to enhance patient care. The initiative emphasizes reducing disparities in cancer treatment across diverse demographics.

Amgen (NASDAQ:AMGN) will host a webcast on December 8, 2020, at 4:00 p.m. ET, following the 62nd American Society of Hematology Annual Meeting. Led by David M. Reese, the call will focus on the company's oncology and hematology programs, particularly the innovative BiTE® platform. Key topics will include the first clinical data for AMG 701 and results from a Phase 3 pediatric study of BLINCYTO® (blinatumomab). The webcast will be available on Amgen's website and archived for 90 days.

Amgen (NASDAQ:AMGN) will present key data at the 62nd American Society of Hematology Annual Meeting from Dec. 5-8, 2020. Highlights include findings from the Phase 1 study of AMG 701, targeting BCMA for relapsed/refractory multiple myeloma. The data also features analyses from the BLINCYTO Phase 3 study for children with high-risk B-ALL. Amgen emphasizes its robust bispecific T cell engager (BiTE®) portfolio, showcasing first-in-human data. Additional presentations will cover updates from the KYPROLIS Phase 3 CANDOR study.

Amgen (NASDAQ:AMGN) is set to present at the Evercore ISI Virtual HealthCONx Conference on Dec. 1, 2020, at 1:50 p.m. ET. Key executives, including David M. Reese and Peter H. Griffith, will lead the presentation. Interested parties can access the live audio on Amgen's website under the Events Calendar, with a replay available for 90 days. Amgen is focused on innovative therapeutics and addressing unmet medical needs, aiming to improve health outcomes globally. More details can be found at www.amgen.com.