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Autonomix Medical Expands Intellectual Property Portfolio with New U.S. Patent Covering Feedback-Guided Precision Neuromodulation and Targeted Therapy Delivery

Autonomix Medical (NASDAQ: AMIX) announced the issuance of U.S. Patent No. 12,714,780 on August 25, 2026, covering systems that integrate real-time physiological feedback, sensing and imaging with controlled delivery of therapeutic agents.

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Autonomix Medical (NASDAQ: AMIX) announced the issuance of U.S. Patent No. 12,714,780 on August 25, 2026, covering systems that integrate real-time physiological feedback, sensing and imaging with controlled delivery of therapeutic agents.

The patent protects medical systems using surgical instruments and controllers to regulate treatment based on feedback signals from targeted or surrounding tissues, including control of therapeutic fluid quantity and distribution. It encompasses applications where targeted tissue includes tumors and therapeutic fluids enable neural ablation to reduce cancer pain, and covers denervating and neuroblocking agents. The patent also addresses monitoring, imaging, stimulating and ablating neurological structures in the lower urinary tract via minimally invasive access routes, and is based on continuation applications dating back to 2012 and 2014.

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Argus Aug 26 session 35 alerts
-11.27% close to close 38.4x rel. volume Open Argus
Details

Market move: AMIX -11.27% in the Aug 26 session. U.S. patent issuance

+21.8% Peak Tracked
-6.7% Trough Tracked
$7.71M Mkt Cap at Peak Alert

On Aug 26, the day this news came out, AMIX closed 11.27% below the previous close. Argus tracked a peak move of +21.8% during that session. Argus tracked a trough of -6.7% from its starting point during tracking. Our momentum scanner recorded 35 alerts for this stock that day. Relative volume reached 38.4x the daily average during tracking.

Data tracked by StockTitan Argus for the Aug 26 session.

Key Figures

U.S. patent number: Patent No. 12,714,780 Patent issuance date: August 25, 2026 Underlying application years: 2012 and 2014
U.S. patent number
Patent No. 12,714,780
Issued by the USPTO
Patent issuance date
August 25, 2026
U.S. patent issuance
Underlying application years
2012 and 2014
Applications traced by the continuation application

Historical Context

5 past events · Latest: Aug 24
5 events
  1. Aug 24

    Warrant inducement

    24h Move
    +33.9%

    Immediate warrant exercise generated proceeds but introduced additional warrants and dilution risk.

  2. Aug 12

    Preclinical study

    24h Move
    -17.4%

    Completed GLP study supported planned FDA submission and future clinical-stage execution.

  3. Aug 10

    Leadership recognition

    24h Move
    -7.5%

    Co-founder and chief medical officer received a cardiovascular technology lifetime achievement award.

  4. Aug 04

    Patent issuance

    24h Move
    +434.3%

    New patent expanded protection for nerve sensing, mapping and targeted therapy delivery.

  5. Jul 24

    Preclinical results

    24h Move
    -16.6%

    Renal nerve sensing and post-ablation neural activity changes were demonstrated in an animal model.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

neuromodulation, neural ablation, continuation application, electrophysiological feedback
4 terms
neuromodulation medical
"additional applications for neuromodulation and targeted ablation"
Neuromodulation is the use of devices or targeted treatments to change how nerves or brain circuits send signals, much like adjusting the volume or tuning on an audio system to alter what you hear. For investors, it matters because these therapies can treat chronic conditions (pain, movement disorders, depression) where existing medicines fall short, creating potential markets, regulatory milestones, and durable revenue streams if technologies prove safe and effective.
neural ablation medical
"therapeutic fluid is configured to effect neural ablation to reduce cancer pain"
Destruction or targeted disruption of nerve tissue to stop or change abnormal nerve signals, accomplished by methods such as heat, cold, chemicals, focused radiation, or energy-based devices; like cutting or disabling a wire so an electrical signal no longer passes. It matters to investors because neural ablation is a therapeutic approach and medical-device area whose safety, effectiveness, regulatory approval, and clinical-trial results determine commercial potential, reimbursement, and market size for companies working in this field.
continuation application regulatory
"The patent is based on a continuation application that traces back"
A continuation application is a follow-up patent filing that keeps the original filing date and uses the same technical description as an earlier (parent) patent application while seeking different or additional patent claims. For investors it matters because continuations can extend or broaden the legal protection around an invention—like adding new rooms to a house without changing the foundation—affecting a company’s competitive position, licensing potential, and the value of its intellectual property portfolio.
electrophysiological feedback technical
"using physiological and electrophysiological feedback to guide and evaluate treatment"
Electrophysiological feedback is the real-time measurement and use of electrical signals from body tissues—such as the heart, brain, or nerves—to monitor function or guide a medical device’s actions. Like a thermostat that senses room temperature and adjusts heating, devices that use this feedback can automatically tune therapy based on a patient's electrical activity. It matters to investors because it is a technical feature that can affect a device’s clinical performance, regulatory review, and market value.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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New patent broadens protection around systems integrating real-time physiological feedback, sensing and imaging with controlled therapeutic delivery, including neural ablation approaches for cancer pain

THE WOODLANDS, TX, Aug. 26, 2026 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc. (NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company dedicated to advancing precision nerve-targeted treatments, today announced the issuance of U.S. Patent No. 12,714,780 by the United States Patent and Trademark Office (USPTO), titled “Systems and Methods for Regulating Organ and/or Tumor Growth Rates, Function, and/or Development” on August 25, 2026.

The newly issued patent covers medical systems incorporating a surgical instrument with one or more delivery elements and a controller configured to regulate treatment based, at least in part, on physiological feedback signals from a targeted tissue region or surrounding tissues. The patent specifically covers systems capable of controlling the quantity and delivery of therapeutic fluid based on its distribution within the targeted tissue, as well as systems incorporating imaging and sensing capabilities. Importantly, the issued patent includes applications in which the targeted tissue region comprises a tumor and the therapeutic fluid is configured to effect neural ablation to reduce cancer pain. The patent also covers the use of denervating agents, sympathetic and parasympathetic nerve-specific denervating agents and neuroblocking agents.

“The issuance of this U.S. patent further strengthens our intellectual property position around precisely controlled, feedback-guided intervention of targeted tissue and neural structures,” said Brad Hauser, Chief Executive Officer of Autonomix Medical. “The breadth of this patent reflects the potential of our technology platform to combine sensing, imaging and targeted therapy delivery to enable more controlled and personalized interventions. We believe this intellectual property provides an important foundation as we continue advancing our technology platform and exploring additional applications for neuromodulation and targeted ablation.”

The patent describes systems and methods for monitoring, imaging, stimulating and/or ablating neurological structures associated with organs of the lower urinary tract, with applications described for modulating organ function, hormone secretion and organ or tumor growth, as well as approaches for accessing neural structures through minimally invasive routes, including through arteries and veins, and using physiological and electrophysiological feedback to guide and evaluate treatment.

The patent is based on a continuation application that traces back to applications filed in 2012 and 2014 and related U.S. patent applications, underscoring the longstanding development of the underlying technology.

About Autonomix Medical, Inc. 

Autonomix is a medical device company focused on advancing innovative technologies to revolutionize how diseases involving the nervous system are diagnosed and treated. The Company’s first-in-class platform system technology includes a catheter-based microchip sensing array that may have the ability to detect and differentiate neural signals with greater sensitivity than currently available technologies. We believe this will enable, for the first time ever, transvascular diagnosis and treatment of diseases involving the peripheral nervous system virtually anywhere in the body. 

We are initially developing this technology for the treatment of pain, with initial trials focused on pancreatic cancer, a condition that causes debilitating pain and is without a reliable solution. Our technology constitutes a platform to address dozens of potential indications, including cardiology, hypertension and chronic pain management, across a wide disease spectrum. Our technology is investigational and has not yet been cleared for marketing in the United States.

For more information, visit autonomix.com and connect with the Company on X, LinkedIn, Instagram and Facebook.

Forward Looking Statements 

Some of the statements in this release are “forward-looking statements,” which involve risks and uncertainties. Such forward-looking statements can be identified by the use of words such as “should,” “might,” “may,” “intends,” “anticipates,” “believes,” “estimates,” “projects,” “forecasts,” “expects,” “plans,” and “proposes.” Forward-looking statements in this press release include, but are not limited to, expectations regarding the potential effectiveness and clinical benefits of Autonomix's nerve-targeted treatments for pancreatic cancer pain and other conditions, the versatility and scalability of the Company's platform technology, the potential for future clinical applications across multiple organ systems, the strength and scope of the Company's intellectual property portfolio, and the potential for the Company's patented technologies to support patient selection, procedural guidance and post-treatment monitoring across multiple neuromodulation applications.

Although Autonomix believes that the expectations reflected in these forward-looking statements are based on reasonable assumptions, there are a number of risks and uncertainties that could cause actual results to differ materially from such forward-looking statements. You are urged to carefully review and consider any cautionary statements and other disclosures, including the statements made under the heading “Risk Factors” and elsewhere in the most recent Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) on May 27, 2026, and from time to time, our other filings with the SEC. Forward-looking statements speak only as of the date of this press release and Autonomix does not undertake any duty to update any forward-looking statements except as may be required by law. 

Investor and Media Contact 

JTC Team, LLC 
Jenene Thomas
908.824.0775
autonomix@jtcir.com


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What patent did Autonomix Medical (NASDAQ: AMIX) receive on August 25, 2026?

Autonomix Medical received U.S. Patent No. 12,714,780 on August 25, 2026, covering feedback-guided neuromodulation and targeted therapy delivery systems. According to Autonomix Medical, it protects systems integrating physiological feedback, imaging, sensing and controlled therapeutic fluid delivery for regulating organ or tumor function and growth.

How does the new Autonomix Medical (AMIX) patent relate to cancer pain treatment?

The patent covers systems where targeted tissue includes tumors and therapeutic fluids are configured for neural ablation to reduce cancer pain. According to Autonomix Medical, it includes use of denervating agents, sympathetic and parasympathetic nerve-specific denervating agents, and neuroblocking agents within these feedback-guided delivery systems.

What technologies are included in Autonomix Medical’s feedback-guided neuromodulation patent for AMIX?

The patent includes surgical instruments with one or more delivery elements and a controller that regulates treatment using physiological feedback signals. According to Autonomix Medical, it also covers systems incorporating imaging and sensing capabilities to control therapeutic fluid quantity and distribution within targeted tissues and surrounding regions.

Does the 2026 Autonomix Medical patent cover lower urinary tract applications?

Yes. The patent describes systems and methods for monitoring, imaging, stimulating and ablating neurological structures associated with lower urinary tract organs. According to Autonomix Medical, applications include modulating organ function, hormone secretion and organ or tumor growth, using minimally invasive access routes such as arteries and veins.

How long has Autonomix Medical’s technology underlying U.S. Patent 12,714,780 been in development?

The patent is based on a continuation application tracing back to filings in 2012 and 2014. According to Autonomix Medical, it also relies on related U.S. patent applications, highlighting more than a decade of development of its feedback-guided neuromodulation and targeted therapy delivery platform.

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