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Autonomix Medical to Present Final Analysis on Pain Mitigation in Pancreatic Cancer at SIO 2026 Annual Scientific Meeting

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Autonomix Medical (NASDAQ: AMIX) will present final clinical data on a transvascular radiofrequency (RF) ablation approach for pain mitigation in pancreatic adenocarcinoma at the SIO 2026 Annual Scientific Meeting in Savannah, GA (Feb 4-8, 2026).

The ePoster (Abstract #327) will be presented by Clarke Wilkirson, PhD on Feb 6, 2026, 5:30–6:30 PM EST, including a 10-minute talk and 5-minute discussion during the Science and Sips reception.

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Negative

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News Market Reaction

-0.14%
1 alert
-0.14% News Effect
-$4K Valuation Impact
$3M Market Cap
0.0x Rel. Volume

On the day this news was published, AMIX declined 0.14%, reflecting a mild negative market reaction. This price movement removed approximately $4K from the company's valuation, bringing the market cap to $3M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Quarterly net loss: $7.5 million Six-month net loss: $10.8 million Cash balance: $7.5 million +5 more
8 metrics
Quarterly net loss $7.5 million Net loss for quarter ended Sep 30, 2025 (Q2 FY2026)
Six-month net loss $10.8 million Net loss for six months ended Sep 30, 2025
Cash balance $7.5 million Cash and cash equivalents at Sep 30, 2025
Equity purchase agreement $15.0 million Equity purchase agreement with Lincoln Park
ATM gross proceeds $2.6 million ATM sales fiscal-to-date through Q2 FY2026
PIPE gross proceeds $5.0 million November 2025 PIPE transaction
Potential warrant proceeds $7.7 million If all Common Warrants are exercised in cash
Warrants registered 13,504,998 shares Shares underlying warrants on S-3 shelf

Market Reality Check

Price: $0.4000 Vol: Volume 222,701 is far bel...
low vol
$0.4000 Last Close
Volume Volume 222,701 is far below the 9,650,213 20-day average, suggesting limited pre-news positioning. low
Technical Shares at 0.4226 are trading below the 1.21 200-day MA and sit 86.63% under the 52-week high.

Peers on Argus

AMIX was down 1.15% while only one momentum peer (MOVE) screened, falling about ...
1 Down

AMIX was down 1.15% while only one momentum peer (MOVE) screened, falling about 4.97%. Other listed peers had mixed, mostly modest moves, indicating this news appears more stock-specific than sector-driven.

Historical Context

5 past events · Latest: Jan 09 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Jan 09 Clinical data update Positive +2.8% ASCO GI subgroup data showing rapid, durable pain relief across disease stages.
Dec 30 Patent grant Positive +8.3% European patent granted on cardiac neuromodulation platform technology.
Dec 23 Investor presentation Positive -7.0% CEO outlined IP strengthening and multi-indication expansion strategy.
Dec 18 Conference abstract Positive +4.6% ASCO GI 2026 poster acceptance on long-term pancreatic pain mitigation data.
Nov 26 CEO commentary Positive +10.2% CEO Corner discussing IP protection and expansion beyond pancreatic cancer.
Pattern Detected

Recent company-specific announcements, especially clinical and IP milestones, have more often been followed by positive price reactions, with only one notable divergence on a strategy-focused CEO event.

Recent Company History

Over the last few months, AMIX has highlighted clinical progress and platform expansion. A Jan 9, 2026 ASCO GI update (news_id 955378) on pancreatic cancer pain relief saw a positive move. Late Dec 2025 brought a European patent grant (news_id 951842) and IP/platform strategy commentary (news_id 951084). Earlier, an ASCO GI poster selection (news_id 949618) and a CEO Corner segment on strategic growth (news_id 941246) also supported an innovation-focused narrative that this SIO presentation announcement fits into.

Regulatory & Risk Context

Active S-3 Shelf · $7.7 million
Shelf Active
Active S-3 Shelf Registration 2025-11-26
$7.7 million registered capacity

An effective S-3 shelf dated Nov 26, 2025 registers 13,504,998 warrant shares for resale; AMIX would receive up to $7.7 million only if the Common Warrants are exercised in cash, and full exercise would significantly increase the share count.

Market Pulse Summary

This announcement adds another visibility milestone for AMIX’s transvascular RF ablation approach in...
Analysis

This announcement adds another visibility milestone for AMIX’s transvascular RF ablation approach in pancreatic cancer by taking final pain-mitigation data to the SIO 2026 meeting. It follows recent ASCO GI presentations and IP-focused updates, reinforcing a strategy centered on clinical validation and platform exposure. At the same time, regulatory filings highlight ongoing net losses of $7.5 million in the last quarter, limited cash of $7.5 million, and reliance on facilities such as a $15.0 million equity purchase agreement and warrant structures for funding.

Key Terms

transvascular radiofrequency (RF) ablation, pancreatic adenocarcinoma, neurolysis, interventional oncology
4 terms
transvascular radiofrequency (RF) ablation medical
"final clinical data evaluating its transvascular radiofrequency (RF) ablation approach for pain"
A minimally invasive medical procedure that sends controlled radiofrequency energy through a thin tube inserted into a blood vessel to heat and destroy targeted tissue, such as small tumors or abnormal heart tissue. Think of it like guiding a focused, tiny hot wire to a precise spot inside the body to remove a problem without open surgery. Investors care because adoption affects demand for specialized devices, hospital capital spending, clinical outcomes, and reimbursement trends, all of which influence market size and revenue potential.
pancreatic adenocarcinoma medical
"Pain Mitigation in Pancreatic Adenocarcinoma: A Final Analysis of Neurolysis via"
Pancreatic adenocarcinoma is a type of cancer that starts in the cells of the pancreas, the organ that helps digestion and controls blood sugar. It matters to investors because it is often aggressive and hard to detect early, so progress or setbacks in diagnostics, drugs or clinical trials can strongly affect the value of companies working on treatments—similar to how a breakthrough or failure in fixing a critical bridge can change the fortunes of contractors and insurers.
neurolysis medical
"A Final Analysis of Neurolysis via Transvascular Radiofrequency (RF) Ablation"
Neurolysis is a medical procedure that deliberately disables or destroys a specific nerve to stop chronic pain signals, using heat, cold, chemicals, or focused energy. For investors, it matters because neurolysis supports demand for specialized devices, disposable tools, drugs and clinic services, and changes in its safety, effectiveness or reimbursement can quickly affect the revenues and prospects of companies in pain management and interventional care—think of it as turning off a faulty wire to stop a house alarm.
interventional oncology medical
"highlighting emerging innovations in interventional oncology"
Interventional oncology is a branch of medicine that uses image-guided, minimally invasive procedures to treat cancer by targeting tumors directly—through techniques such as precise heat, cold, chemical delivery, or blocking a tumor's blood supply. Investors care because it drives demand for specialized devices, hospital services and repeatable outpatient procedures, and can change treatment costs and patient outcomes much like a targeted tool that removes a weed without digging up the whole garden.

AI-generated analysis. Not financial advice.

THE WOODLANDS, TX, Jan. 28, 2026 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc. (NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company dedicated to advancing precision nerve-targeted treatments, today announced that final clinical data evaluating its transvascular radiofrequency (RF) ablation approach for pain mitigation in pancreatic adenocarcinoma will be presented at the Society of Interventional Oncology (SIO) 2026 Annual Scientific Meeting happening February 4-8, 2026 in Savannah, GA.

The presentation, titled “Pain Mitigation in Pancreatic Adenocarcinoma: A Final Analysis of Neurolysis via Transvascular Radiofrequency (RF) Ablation,” has been accepted as an ePoster presentation for the conference’s Science and Sips Reception, highlighting emerging innovations in interventional oncology.

The ePoster (Abstract #327) will be presented by Clarke Wilkirson, PhD on Friday, February 6, 2026, from 5:30 PM to 6:30 PM EST, in the ePoster corridor outside the exhibit hall. As part of the Science and Sips program, the presentation will include a dedicated 15-minute session consisting of a 10-minute presentation followed by a 5-minute discussion period.

“Pain remains one of the most debilitating and difficult-to-treat complications for patients with pancreatic cancer,” said Dr. Robert Schwartz, Co-Founder and Chief Medical Officer of Autonomix. “We are pleased to present the final analysis of this study at the SIO 2026 Annual Scientific Meeting, as it highlights the potential of our transvascular RF ablation approach to address a significant unmet clinical need. We believe this minimally invasive therapy may offer a meaningful opportunity to improve pain control and quality of life for patients facing this devastating disease.”

The SIO Annual Scientific Meeting brings together leading clinicians, researchers and innovators focused on advancing minimally invasive, image-guided therapies for cancer care. For more details, please visit the conference website here.

About Autonomix Medical, Inc.

Autonomix is a medical device company focused on advancing innovative technologies to revolutionize how diseases involving the nervous system are diagnosed and treated. The Company’s first-in-class platform system technology includes a catheter-based microchip sensing array that may have the ability to detect and differentiate neural signals with greater sensitivity than currently available technologies. We believe this will enable, for the first time ever, transvascular diagnosis and treatment of diseases involving the peripheral nervous system virtually anywhere in the body.

We are initially developing this technology for the treatment of pain, with initial trials focused on pancreatic cancer, a condition that causes debilitating pain and is without a reliable solution. Our technology constitutes a platform to address dozens of potential indications, including cardiology, hypertension and chronic pain management, across a wide disease spectrum. Our technology is investigational and has not yet been cleared for marketing in the United States.

For more information, visit autonomix.com and connect with the Company on X, LinkedIn, Instagram and Facebook.

Forward Looking Statements

Some of the statements in this release are “forward-looking statements,” which involve risks and uncertainties. Such forward-looking statements can be identified by the use of words such as “should,” “might,” “may,” “intends,” “anticipates,” “believes,” “estimates,” “projects,” “forecasts,” “expects,” “plans,” and “proposes.” Forward-looking statements in this press release include expectations regarding the potential effectiveness and clinical benefits of Autonomix's nerve-targeted treatments for pancreatic cancer pain and other conditions.

Although Autonomix believes that the expectations reflected in these forward-looking statements are based on reasonable assumptions, there are a number of risks and uncertainties that could cause actual results to differ materially from such forward-looking statements. You are urged to carefully review and consider any cautionary statements and other disclosures, including the statements made under the heading “Risk Factors” and elsewhere in the Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) on May 29, 2025, and from time to time, our other filings with the SEC. Forward-looking statements speak only as of the date of this press release and Autonomix does not undertake any duty to update any forward-looking statements except as may be required by law.

Investor and Media Contact

JTC Team, LLC
Jenene Thomas
908.824.0775
autonomix@jtcir.com


FAQ

When will Autonomix (AMIX) present the final analysis on RF ablation at SIO 2026?

Autonomix will present on Feb 6, 2026 from 5:30–6:30 PM EST. According to Autonomix, the ePoster (Abstract #327) is scheduled in the ePoster corridor with a 10-minute presentation and 5-minute discussion.

What is the focus of Autonomix's (AMIX) ePoster Abstract #327 at SIO 2026?

The ePoster presents a final analysis of neurolysis via transvascular RF ablation for pancreatic adenocarcinoma pain mitigation. According to Autonomix, the data evaluate a minimally invasive approach to improve pain control and quality of life.

Who will present Autonomix's (AMIX) final clinical data at the SIO 2026 meeting?

Clarke Wilkirson, PhD will present the ePoster on behalf of Autonomix. According to Autonomix, the presentation is part of the Science and Sips reception and includes a brief discussion period after the talk.

Where and in what format will Autonomix (AMIX) present its SIO 2026 findings?

The presentation will be an ePoster in the ePoster corridor outside the exhibit hall at SIO 2026. According to Autonomix, it is an accepted ePoster with a 15-minute slot during the Science and Sips program.

How does Autonomix (AMIX) describe the clinical relevance of the transvascular RF approach?

Autonomix describes the approach as a potential minimally invasive therapy to improve pain control and quality of life. According to Autonomix, the final analysis highlights potential to address a significant unmet clinical need in pancreatic cancer.
Autonomix Medical Inc

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THE WOODLANDS