Welcome to our dedicated page for Anaptysbio news (Ticker: ANAB), a resource for investors and traders seeking the latest updates and insights on Anaptysbio stock.
AnaptysBio, Inc. (Nasdaq: ANAB) generates a steady flow of news as a clinical-stage biotechnology company focused on immunology therapeutics for autoimmune and inflammatory diseases. News coverage on this page centers on its internal pipeline, royalty-bearing collaborations, corporate strategy and legal developments.
Investors following ANAB news will see updates on rosnilimab, a pathogenic T cell depleter that has completed a Phase 2b trial in rheumatoid arthritis and has been evaluated in ulcerative colitis, as well as early-stage programs ANB033 and ANB101. Company announcements describe clinical data readouts, safety and efficacy findings, and decisions to advance or discontinue specific trials, such as the discontinuation of a Phase 2 ulcerative colitis study after not meeting primary and key secondary endpoints at Week 12.
Another key news theme is AnaptysBio’s financial collaborations. Releases detail royalty and milestone expectations from Jemperli (dostarlimab-gxly), the PD-1 antagonist licensed to GSK through Tesaro, and from imsidolimab, the IL-36 receptor antagonist licensed to Vanda Pharmaceuticals. Updates from partners, such as Vanda’s Biologics License Application submission for imsidolimab, also feature prominently because AnaptysBio holds the underlying license.
Corporate and capital allocation developments appear in ANAB news as well, including the company’s intent to separate its biopharma operations from its substantial royalty assets by the end of 2026 and board-authorized stock repurchase plans. Legal and regulatory items, such as AnaptysBio’s litigation with Tesaro and GSK over the Jemperli collaboration and related SEC Form 8-K filings, also contribute to the news flow. This page aggregates these announcements so readers can track how clinical results, royalty assets, strategic separation plans and legal proceedings may shape AnaptysBio’s trajectory over time.
On March 8, 2021, AnaptysBio reported that its Phase 2 trial of imsidolimab for moderate-to-severe palmoplantar pustulosis (PPP) did not meet the primary endpoint of statistically significant improvement over placebo at week 16. The treatment was well tolerated, with no serious adverse events reported. AnaptysBio will not pursue further development in PPP but will advance imsidolimab in five other indications, including a Phase 3 trial in generalized pustular psoriasis (GPP) expected in mid-2021. Key results showed similar levels of improvement between treatment and placebo groups, with p-values indicating no significant differences.
AnaptysBio (Nasdaq: ANAB) reported positive topline data from its Phase 2 GALLOP trial of imsidolimab for generalized pustular psoriasis (GPP) in 2020, with Phase 3 initiation expected mid-2021. Additionally, the company is expanding imsidolimab trials into other dermatological conditions and has advanced ANB030 into Phase 1 trials. Key financial updates include a decrease in cash to $411.2 million, while collaboration revenue surged to $75 million due to milestone payments. The net income for Q4 2020 was $33.6 million, reflecting progress despite an annual net loss of $19.9 million.
AnaptysBio, a clinical-stage biotechnology company (Nasdaq: ANAB), announced that CEO Hamza Suria will present at the 39th Annual J.P. Morgan Healthcare Conference on January 14, 2021, at 9:10 a.m. ET. The virtual presentation will be available via a webcast, with a replay accessible for 30 days post-event. AnaptysBio specializes in developing first-in-class antibody product candidates targeting inflammation and immuno-oncology. Their pipeline includes treatments for rare inflammatory diseases and chronic conditions, utilizing a proprietary antibody discovery platform.
AnaptysBio, a clinical-stage biotechnology company (Nasdaq: ANAB), has announced that CEO Hamza Suria will present at the 2020 Jefferies London Virtual Healthcare Conference on November 17, 2020, at 12:35 p.m. ET. The conference will be held virtually, with a live presentation accessible on AnaptysBio’s investor website.
AnaptysBio specializes in first-in-class antibody product candidates targeting immune control mechanisms for inflammation and immuno-oncology. Their pipeline includes several innovative candidates like imsidolimab and ANB030, developed using their proprietary somatic hypermutation platform.
AnaptysBio reported promising interim results from its GALLOP Phase 2 trial of imsidolimab for treating moderate to severe Generalized Pustular Psoriasis (GPP), with a 94% reduction in skin pustules after 29 days. The company expects to engage with the FDA for a registration path in Q4 2020. Additionally, the POPLAR Phase 2 trial for palmoplantar pustulosis has been fully enrolled, and topline data is expected in Q1 2021. An amended collaboration with GlaxoSmithKline aims to enhance dostarlimab royalties, with $20 million in milestone payments anticipated for 2020.
AnaptysBio, a clinical-stage biotechnology company, announced an amendment to its collaboration agreement with GlaxoSmithKline (GSK) that significantly increases royalties on its immuno-oncology drug, dostarlimab. The royalty rates will now range from 8% to 25% of global net sales, with an anticipated FDA approval for endometrial cancer in Q4 2020. Additionally, GSK will make a one-time cash payment of $60 million and provide a 1% royalty on Zejula™ sales starting January 2021. AnaptysBio expects $75 million in cash milestones over the next 18 months.
AnaptysBio announced positive topline data from the Phase 2 GALLOP trial of imsidolimab for treating generalized pustular psoriasis (GPP). Six out of eight patients achieved the primary endpoint of clinical improvement on Day 29, with skin pustules decreasing by 60% by Day 8 and 94% by Day 29. The company anticipates an FDA end-of-Phase 2 meeting in Q4 2020 to discuss the registration pathway. Additionally, the Phase 2 trial for palmoplantar pustulosis will provide top-line data in Q1 2021, as will the initiation of a global registry for GPP and PPP patients.
AnaptysBio, a clinical-stage biotechnology company focused on antibody development, announced that CEO Hamza Suria will present at the 2020 Cantor Global Virtual Healthcare Conference on September 17, 2020, at 12:00 p.m. ET. The presentation will be accessible online, with a replay available for 90 days post-event. AnaptysBio's pipeline includes anti-IL-36R antibody imsidolimab and anti-IL-33 antibody etokimab, targeting rare inflammatory diseases and chronic conditions. The company employs a proprietary somatic hypermutation platform for antibody discovery.
AnaptysBio reported interim 8-week data from the ECLIPSE Phase 2 trial for etokimab, showing no statistically significant improvement in chronic rhinosinusitis with nasal polyps compared to placebo. The company plans to evaluate the program's future after analyzing complete 16-week data by year-end 2020. Meanwhile, the Imsidolimab program received orphan drug designation, and additional top-line data is expected in Q4 2020. Financially, the company reported a Q2 net loss of $21.5 million with cash reserves of $392.2 million, projecting a cash burn of $60 million for 2020.
AnaptysBio, a clinical-stage biotechnology company focused on antibody development, announced that CEO Hamza Suria will present at the 2020 Wedbush PacGrow Healthcare Conference on August 11, 2020, at 2:55 p.m. ET. The conference will be virtual, and the presentation can be accessed via a provided link. AnaptysBio's pipeline includes innovative therapies targeting inflammation and immuno-oncology, such as etokimab for chronic rhinosinusitis and imsidolimab for rare inflammatory diseases. A replay of the presentation will be available for 90 days post-event.