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Anixa Biosciences Announces Presentation of its Ovarian Cancer CAR-T Therapy at the International Society for Cell & Gene Therapy 2026 Annual Meeting

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Anixa (NASDAQ: ANIX) announced a presentation on its ovarian cancer CAR-T therapy, lira-cel, at the International Society for Cell & Gene Therapy (ISCT) 2026 Annual Meeting in Dublin, May 6–9, 2026.

The presentation will cover the Phase 1 trial design, objectives, and the current status, with the company noting that lira-cel continues to show positive survival data in the ongoing study.

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Positive

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Negative

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News Market Reaction – ANIX

+9.03% 2.1x vol
11 alerts
+9.03% Session close to close
+3.3% Peak in 1 hr 39 min
$105.95M Market Cap
2.1x Rel. Volume

In the Apr 22 session, ANIX gained 9.03%, reflecting a notable positive market reaction. Argus tracked a peak move of +3.3% during that session. Our momentum scanner triggered 11 alerts that day, indicating notable trading interest and price volatility. Trading volume was elevated at 2.1x the daily average, suggesting notable buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved +9.0% in the session following this news. A strong positive reaction aligns with rec...
Analysis

The stock moved +9.0% in the session following this news. A strong positive reaction aligns with recurring updates on Anixa’s ovarian cancer CAR-T program, where Phase 1 data have highlighted encouraging survival and safety signals. Past news on this program and the breast cancer vaccine often saw modest gains, suggesting investors respond to clinical progress. However, the company remains pre-revenue with a recent quarterly net loss of $2.565M and cash of $14.202M, so further financing and data milestones would remain key risk factors.

Key Figures

Net loss: $2.565M Prior-year net loss: $3.184M R&D expenses: $1.102M +5 more
8 metrics
Net loss $2.565M Quarter ended Jan 31, 2026; improved from prior-year loss
Prior-year net loss $3.184M Quarter ended Jan 31, 2025
R&D expenses $1.102M Quarter ended Jan 31, 2026
G&A expenses $1.614M Quarter ended Jan 31, 2026
Cash & investments $14.202M As of Jan 31, 2026
ATM proceeds $1.625M Raised via at-the-market stock offering
Patients treated 13 patients Ovarian cancer CAR-T Phase 1 dose-escalation trial
Shares entitled to vote 33,379,505 shares 2026 annual meeting record date

Historical Context

5 past events · Latest: Apr 09 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Apr 09 Conference participation Positive +0.4% Biotech conference presentation covering pipeline and positive Phase 1 data.
Apr 07 Conference participation Positive +3.9% Virtual conference talk on company strategy and clinical program highlights.
Apr 06 Media interview Positive +1.6% CEO interview emphasizing advancing immunotherapy pipeline and early results.
Apr 01 Clinical trial update Positive +5.4% Positive final Phase 1 breast cancer vaccine results and Phase 2 preparation.
Mar 30 Clinical trial presentation Positive -2.0% Ovarian CAR-T Phase 1 trial update at a gynecologic oncology meeting.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent positive clinical and visibility updates have more often been followed by modest share gains, with occasional divergences on conference-style announcements.

Recent Company History

Over the last few months, ANIX has highlighted steady progress across its immunotherapy pipeline. Updates included multiple conference and virtual presentation announcements in early April 2026 and stronger Phase 1 data for both its breast cancer vaccine and ovarian CAR-T therapy. These events generally saw small positive price reactions, especially the Apr 1 breast cancer Phase 1 update, while one ovarian CAR-T conference presentation on Mar 30 drew a slight negative move. Today’s ISCT presentation continues that pattern of scientific visibility rather than new topline data.

Key Terms

car-t, autologous t cells, chimeric receptor, follicle-stimulating hormone receptor (fshr), +4 more
8 terms
car-t medical
"Anixa Biosciences Announces Presentation of its Ovarian Cancer CAR-T Therapy..."
CAR-T is a type of cancer therapy that reprograms a patient’s own immune cells to seek and destroy specific cancer cells, like teaching guard dogs a new scent to track intruders. It matters to investors because CAR-T treatments can command high prices, drive strong revenue for successful developers, and carry regulatory and manufacturing risks that can sharply affect a company’s valuation and long-term growth prospects.
autologous t cells medical
"Phase 1 clinical trial of autologous T cells genetically engineered..."
Autologous T cells are a patient’s own immune cells taken out, sometimes modified or multiplied in a lab, and then returned to help fight disease. Think of it as customizing and strengthening a person’s own soldiers rather than bringing in outsiders; for investors this signals highly personalized, potentially powerful therapies but also complex manufacturing, higher costs, and regulatory hurdles that affect commercial scale and profitability.
chimeric receptor medical
"genetically engineered with a chimeric receptor to target the follicle-stimulating..."
A chimeric receptor is an engineered protein made by stitching together parts from different natural receptors so a cell can recognize new signals or respond in new ways—think of attaching a new sensor to an existing machine. For investors, these receptors are central to many cutting‑edge therapies because they can reprogram cells to target disease; their success affects drug pipelines, regulatory reviews, manufacturing complexity, and the commercial potential of biotech companies.
follicle-stimulating hormone receptor (fshr) medical
"to target the follicle-stimulating hormone receptor (FSHR) in recurrent ovarian cancer"
Follicle-stimulating hormone receptor (FSHR) is a protein on the surface of certain cells that binds follicle-stimulating hormone and triggers signals controlling reproductive processes and some cell growth. It matters to investors because FSHR is a common drug target and diagnostic marker; therapies or tests that modify or measure its activity can create new products, revenue streams, or regulatory risks in fertility, hormonal and certain oncology markets — like a lock where drugs are keys that open or block biological effects.
gene editing medical
"covering advances in areas such as gene editing, bioprocessing, and clinical translation"
Gene editing is a set of laboratory techniques that change the DNA inside living cells to add, remove, or alter specific genes, like using precise 'cut-and-paste' tools to edit an instruction manual for a living organism. It matters to investors because successful edits can produce new therapies, improve agricultural products, or create commercial advantages; progress, safety, regulatory approvals, and patent control all affect a company’s value and risk profile.
bioprocessing technical
"covering advances in areas such as gene editing, bioprocessing, and clinical translation"
Bioprocessing is the set of manufacturing steps that use living cells or biological ingredients to make medicines, vaccines, diagnostics, or other biological products. Think of it as an assembly line where living systems, rather than machines, create the final product; variations in scale, consistency and cost directly affect a product’s ability to reach patients and generate revenue. Investors watch bioprocessing for its impact on production risk, regulatory approval and profit margins.
clinical translation medical
"interactive sessions covering advances in areas such as gene editing, bioprocessing, and clinical translation"
Clinical translation is the process of taking a laboratory discovery—like a drug, diagnostic test, or medical device—and developing it through early human studies and practical steps so it can be used safely and effectively in patients. It matters to investors because progress through clinical translation reduces scientific and regulatory risk and makes a product closer to commercial sale; think of it as moving a prototype toward a factory-ready product, a transition that often unlocks partnerships, funding, and higher valuation.
cell & gene therapy medical
"International Society for Cell & Gene Therapy (ISCT) 2026 Annual Meeting"
Treatments that change a patient’s own cells or their genetic instructions to prevent, cure, or manage disease; gene therapy edits or supplies DNA, while cell therapy gives living cells that perform a therapeutic job. Investors watch these approaches because they can offer one-time or long-lasting cures with large market potential but come with high research costs, strict regulation and binary clinical outcomes that can sharply move a company’s value.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Lira-cel continues to exhibit positive survival data in ongoing Phase 1 clinical trial

SAN JOSE, Calif., April 22, 2026 /PRNewswire/ -- Anixa Biosciences, Inc. ("Anixa" or the "Company") (NASDAQ: ANIX), a biotechnology company focused on the treatment and prevention of cancer, today announced that Cheryl Cox, MHA, Operations Director of the Cell Therapies and Gene Expression Engineering Facility at Moffitt Cancer Center, will be presenting at the International Society for Cell & Gene Therapy (ISCT) 2026 Annual Meeting, being held May 6 – 9, 2026, in Dublin, Ireland.

Ms. Cox's presentation, titled "Phase 1 clinical trial of autologous T cells genetically engineered with a chimeric receptor to target the follicle-stimulating hormone receptor (FSHR) in recurrent ovarian cancer," will discuss the clinical trial design and objectives, as well as the current status of Anixa's ongoing Phase 1 clinical trial of lira-cel.

The ISCT 2026 Annual Meeting will bring together thousands of global experts in cell and gene therapy. This event is recognized as the largest conference focused on translating cell and gene therapies from research to clinical practice. The four-day program will feature hundreds of speakers, cutting edge scientific presentations, and interactive sessions covering advances in areas such as gene editing, bioprocessing, and clinical translation, alongside extensive networking opportunities and industry showcases.

About Lira-cel, Anixa's CAR-T Therapy for Recurrent Ovarian Cancer
Liraltagene autoleucel, or lira-cel, uniquely targets the follicle-stimulating hormone receptor (FSHR), which is selectively expressed on ovarian cells, tumor vasculature, and certain cancer cells, but not in healthy tissue. The ongoing Phase 1 trial (ClinicalTrials.gov NCT05316129) is enrolling adult women with recurrent ovarian cancer who have progressed after at least two prior therapies.

About Anixa Biosciences, Inc.
Anixa is a clinical-stage biotechnology company focused on the treatment and prevention of cancer. Anixa's therapeutic portfolio consists of liraltagene autoleucel, or lira-cel, an ovarian cancer immunotherapy being developed in collaboration with Moffitt Cancer Center, which uses a novel type of CAR-T, known as chimeric endocrine receptor-T cell (CER-T) technology. This technology is differentiated from other cell therapies as the natural ligand of the FSHR receptor, FSH, binds to the FSHR receptor on the tumor cell instead of an antibody fragment. Moffitt is a world leader in cancer immunotherapy treatments, pioneering next-generation cell therapies such as CAR-T, and tumor infiltrating lymphocytes (TILs) to harness the power of the immune system. The Company's vaccine portfolio includes vaccines being developed in collaboration with Cleveland Clinic to treat and prevent breast cancer and ovarian cancer, as well as additional cancer vaccines to address many intractable cancers, including high incidence malignancies in lung, colon, and prostate. These vaccine technologies focus on immunizing against "retired" proteins that have been found to be expressed in certain forms of cancer. The breast and ovarian cancer vaccines were developed at Cleveland Clinic and exclusively licensed to Anixa. Cleveland Clinic is entitled to royalties and other commercialization revenues from the Company related to these vaccine technologies. Anixa's unique business model of partnering with world-renowned research institutions on all stages of development allows the Company to continually examine emerging technologies in complementary fields for further development and commercialization. To learn more, visit www.anixa.com or follow Anixa on LinkedIn, X, Facebook and YouTube.

Forward-Looking Statements
Statements that are not historical fact may be considered forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are not statements of historical facts, but rather reflect Anixa's current expectations concerning future events and results. We generally use the words "believes," "expects," "intends," "plans," "anticipates," "likely," "will" and similar expressions to identify forward-looking statements. Such forward-looking statements, including those concerning our expectations, involve risks, uncertainties and other factors, some of which are beyond our control, which may cause our actual results, performance or achievements, or industry results, to be materially different from any future results, performance, or achievements expressed or implied by such forward-looking statements. These risks, uncertainties and factors include, but are not limited to, those factors set forth in "Item 1A - Risk Factors" and other sections of our most recent Annual Report on Form 10-K as well as in our Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. We undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. You are cautioned not to unduly rely on such forward-looking statements when evaluating the information presented in this press release.

Contact:
Mike Catelani
President, COO & CFO
mcatelani@anixa.com
408-708-9808

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/anixa-biosciences-announces-presentation-of-its-ovarian-cancer-car-t-therapy-at-the-international-society-for-cell--gene-therapy-2026-annual-meeting-302749566.html

SOURCE Anixa Biosciences, Inc.

FAQ

What will Anixa (ANIX) present about lira-cel at ISCT 2026 on May 6–9, 2026?

Anixa will present Phase 1 clinical trial design, objectives, and status for lira-cel in recurrent ovarian cancer. According to the company, the presentation details autologous T cells engineered to target FSHR and summarizes ongoing safety and survival observations in the trial.

Does Anixa (ANIX) report clinical data on lira-cel at the ISCT 2026 meeting?

Yes, Anixa indicates lira-cel continues to exhibit positive survival data in its ongoing Phase 1 trial. According to the company, the presentation will discuss current status and clinical endpoints without providing full trial readouts at the conference.

Where and when is Anixa's (ANIX) lira-cel presentation at ISCT 2026 held?

The presentation takes place at the ISCT 2026 Annual Meeting in Dublin, Ireland, May 6–9, 2026. According to the company, Cheryl Cox from Moffitt Cancer Center will present on the Phase 1 trial during the four-day program.

What patient population is targeted by Anixa's (ANIX) lira-cel Phase 1 trial?

Lira-cel targets patients with recurrent ovarian cancer using T cells engineered to recognize the follicle-stimulating hormone receptor (FSHR). According to the company, the Phase 1 trial focuses on safety, feasibility, and early signs of clinical benefit including survival outcomes.

How might the ISCT 2026 presentation affect Anixa (ANIX) investor awareness?

The ISCT presentation could raise scientific and investor visibility for Anixa's CAR-T program among peers and clinicians. According to the company, showcasing Phase 1 status and survival observations at a major conference may increase interest from researchers and potential collaborators.