Welcome to our dedicated page for Appili Ther news (Ticker: APLIF), a resource for investors and traders seeking the latest updates and insights on Appili Ther stock.
News about Appili Therapeutics Inc. (APLIF) focuses on its progress as an infectious disease biopharmaceutical company developing anti-infective therapies and medical countermeasures. Company updates highlight commercial performance of its FDA-approved metronidazole oral suspension LIKMEZ, advancement of its tularemia vaccine candidate ATI-1701, development of the topical antiparasitic ATI-1801 for cutaneous leishmaniasis, and its collaboration with Vitalex Biosciences on the fungal vaccine program VXV-01.
Investors and observers following Appili’s news can track announcements on government contracts and grants, including cooperative agreements with the U.S. Air Force Academy and a NIAID contract valued at up to US$40 million for VXV-01. Releases also describe multiple additional U.S. federal funding proposals that could support manufacturing, nonclinical and preclinical studies, regulatory work, IND submissions, and Phase 1 clinical trials across the company’s pipeline.
Regular news items include financial and operational results, scientific publications in peer-reviewed journals, and presentations at sector events such as the NATO Chemical, Biological, Radiological and Nuclear Conference, the BARDA Innovation Symposium, and biodefense consortium meetings. These updates provide context on ATI-1701’s preclinical data, ATI-1801’s regulatory interactions with the FDA, and LIKMEZ patent developments and commercialization activities.
By reviewing Appili Therapeutics news on this page, readers can follow how the company’s infectious disease and biodefense programs evolve over time, how non-dilutive government funding contributes to its development plans, and how its commercial and pipeline assets may influence the outlook for APLIF stock.
Appili Therapeutics Inc. (TSX: APLI; OTCPink: APLIF) announces its special meeting of shareholders on November 6, 2024, to vote on the acquisition by Aditxt Inc. through its subsidiary Adivir, Inc. The arrangement offers shareholders US$0.467 in cash and 0.000686251 Aditxt shares per Appili share. Appili's board recommends voting in favor of the resolution. The deal aims to accelerate Appili's programs, enhance access to capital, and leverage Aditxt's expertise in development and commercialization.
Key highlights include:
- Advancing LIKMEZ™, an FDA-approved liquid oral reformulation of metronidazole
- Accelerating ATI-1701 development towards IND submission in 2025
- Advancing clinical development of ATI-1801 for cutaneous leishmaniasis
- Exploring additional infectious disease development opportunities
Appili Therapeutics Inc. (TSX: APLI; OTCPink: APLIF), a biopharmaceutical company focused on infectious diseases and medical countermeasures, held its annual and special meeting of shareholders on September 17, 2024. All tabled resolutions were approved, including the election of six directors: Don Cilla, Brian Bloom, Theresa Matkovits, Juergen Froehlich, Armand Balboni, and Prakash Gowd. The shareholders also approved the re-appointment of PricewaterhouseCoopers, LLP as the independent auditor, and passed special resolutions for the Company's continuation from the Canada Business Corporations Act to the Ontario Business Corporations Act (OBCA). Additionally, shareholders authorized the board to set the number of directors within the limits set in the Company's articles, in accordance with the OBCA.
Aditxt Inc. (NASDAQ: ADTX) has announced a third amendment to its arrangement agreement with Appili Therapeutics Inc. (TSX: APLI; OTCPink: APLIF). Key changes include:
1. Extending the Outside Date to November 19, 2024
2. Requiring Appili to convene a shareholder meeting promptly
3. Changing the deadline for Aditxt's financing completion to October 18, 2024
4. Making the Continuance a condition for completing the arrangement
The transaction remains subject to Aditxt raising at least $20 million in financing and other customary conditions. Upon completion of the Appili and Evofem Biosciences transactions, Aditxt plans to introduce two new programs focused on public health and women's health, expanding its current immune health and precision health programs.
Appili Therapeutics Inc. (TSX:APLI; OTCPink: APLIF) reported its Q1 FY2025 financial results, ending June 30, 2024. Key highlights include:
1. A definitive agreement with Aditxt, offering a premium to shareholders if approved.
2. ATI-1701 secured $14 million in USAFA funding commitments.
3. FDA engagement for ATI-1801's registration strategy.
4. LIKMEZ™ (ATI-1501) launched in the US market.
5. Net loss of $1.6 million ($0.01 per share), slightly higher than Q1 FY2024.
6. Cash position of $0.3 million as of June 30, 2024.
The company is advancing its infectious disease programs, focusing on ATI-1701, ATI-1801, and LIKMEZ™, aiming to benefit patients and shareholders.
Aditxt (NASDAQ: ADTX) has signed a second amendment to the arrangement agreement with Appili Therapeutics, targeting a September 30, 2024 closing date for the acquisition. The deal involves Aditxt acquiring all issued and outstanding Class A common shares of Appili through a court-approved plan. Key conditions include Aditxt raising at least US$20 million in financing before closing.
Appili has raised over CAD $100 million since 2015 for developing therapeutics in the global infectious disease and biodefense markets. Their portfolio includes LIKMEZ™, an FDA-approved antibiotic suspension, ATI-1701, a tularemia vaccine, and ATI-1801, a topical antiparasitic product. Two programs are potentially eligible for FDA Priority Review Vouchers, subject to legislation renewal.
Appili Therapeutics reported its fiscal year 2024 results, highlighting the FDA approval and commercial launch of LIKMEZ (ATI-1501) for metronidazole oral suspension. The company secured funding from the U.S. Air Force Academy to advance ATI-1701, a biodefense vaccine, and is engaging with regulatory authorities regarding ATI-1801, a topical antiparasitic product.
Financially, Appili experienced a net loss of $3.8 million, an improvement from the $9.2 million loss in the previous year, aided by an increase in government assistance and revenue. The company reported cash reserves of $0.1 million as of March 31, 2024, compared to $2.5 million the prior year, and highlighted a going concern note due to reliance on closing a transaction with Aditxt and other funding.
Appili entered an agreement with Aditxt, where shareholders would receive a combination of cash and stock, contingent on Aditxt raising additional capital. The deal is expected to finalize by Q3 2024.
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