Welcome to our dedicated page for Apellis Pharmace news (Ticker: APLS), a resource for investors and traders seeking the latest updates and insights on Apellis Pharmace stock.
Apellis Pharmaceuticals, Inc. reports news on its commercial-stage biopharmaceutical business centered on complement science and C3-targeting medicines. Recurring updates cover SYFOVRE, a pegcetacoplan injection for geographic atrophy secondary to age-related macular degeneration, and EMPAVELI, pegcetacoplan for rare diseases including paroxysmal nocturnal hemoglobinuria and rare kidney indications.
Company news also includes product revenue updates, ophthalmology and nephrology data presentations, pipeline references tied to complement biology, board and governance changes, investor conference participation, collaboration matters, and corporate-status developments involving strategic transactions and related shareholder communications.
Apellis Pharmaceuticals (Nasdaq: APLS) announced participation in two upcoming investor conferences in March 2022. The Cowen 42nd Annual Health Care Conference will feature a fireside chat on March 9, 2022, at 12:50 p.m. ET, while the Oppenheimer 32nd Annual Healthcare Conference will take place on March 16, 2022, at 12:40 p.m. ET. Both events will be accessible via live webcast on the company’s website, with replays available for 90 days post-event. Apellis focuses on innovative therapies for diseases linked to the complement system.
Apellis Pharmaceuticals reported $15.1 million in net product revenues for EMPAVELI in 2021, marking a successful U.S. launch post-FDA approval for PNH treatment. The company aims to submit a New Drug Application for pegcetacoplan in geographic atrophy by 2Q 2022. Apellis has a promising pipeline with four late-stage and three pre-clinical programs. However, 2021 saw a significant net loss of $746.4 million, up from a $344.9 million loss in 2020, driven by increased R&D expenses totaling $425.9 million.
Apellis Pharmaceuticals (Nasdaq: APLS) will host a conference call and webcast to discuss its fourth quarter and full year 2021 financial results on February 28, 2022, at 4:30 p.m. ET. The call aims to provide insights into the company's performance and future projections. To participate, stakeholders must pre-register for the call. Additionally, a replay of the webcast will be available for 30 days post-event. Apellis is known for developing targeted C3 therapies for various diseases driven by complement cascade activation.
Apellis Pharmaceuticals (APLS) announced the approval of equity inducement awards for a new employee, effective January 3, 2022. The award consists of options to purchase 60,000 shares at an exercise price of $48.77 and 20,000 restricted stock units (RSUs). The options will vest over four years, with 25% vesting on the first anniversary. This action is aligned with Nasdaq Listing Rule 5635(c)(4) and aims to attract talent by providing long-term incentive compensation.
Apellis Pharmaceuticals (Nasdaq: APLS) will present virtually at the 40th Annual J.P. Morgan Healthcare Conference on January 10, 2022, at 8:15 a.m. ET. The presentation will include a live Q&A session and will be accessible via a webcast on the company’s website. A replay will be available for 30 days post-event, along with the presentation slides posted online at 8:00 a.m. ET on the same day. Apellis is focused on developing transformative therapies targeting the complement system for various debilitating diseases.
Apellis Pharmaceuticals announced that the European Commission has approved Aspaveli (pegcetacoplan), the first targeted C3 therapy for paroxysmal nocturnal hemoglobinuria (PNH), aimed at adults who remain anemic after C5 inhibitor treatment. This approval is based on the PEGASUS Phase 3 study showing Aspaveli's effectiveness over eculizumab in improving hemoglobin levels. Aspaveli will enjoy market exclusivity in the EU due to its orphan drug designation, supporting its potential to enhance patient care for PNH.
Apellis Pharmaceuticals (Nasdaq: APLS) and Sobi™ announced positive data for Empaveli™ (pegcetacoplan) in treating paroxysmal nocturnal hemoglobinuria (PNH) at the ASH Annual Meeting. Results from the Phase 3 PRINCE study revealed significant improvements in treatment-naïve patients: 46% achieved hemoglobin normalization without transfusions, with a mean hemoglobin rise from 9.4 g/dL to 12.8 g/dL. The treatment also resulted in rapid reductions in lactate dehydrogenase (LDH) levels. The safety profile was consistent, with lower serious adverse events compared to standard care.
Apellis Pharmaceuticals (Nasdaq: APLS) will present at the 4th Annual Evercore ISI HealthCONx Conference on December 2, 2021, at 8:00 a.m. ET. The presentation will be conducted in a virtual format and can be accessed via a live webcast on the company’s website. A replay of the event will be available for 90 days post-conference. Apellis is a global leader in complement therapies, focusing on innovative treatments for diseases related to the complement cascade in various fields, including hematology and neurology.
Apellis Pharmaceuticals (APLS) announced the closing of its underwritten public offering, selling a total of 10,062,500 shares at $40.00 each. This offering generated gross proceeds of approximately $402.5 million before expenses. The underwriters fully exercised their option to purchase an additional 1,312,500 shares. The offering was conducted under an effective shelf registration statement filed with the SEC.
Apellis focuses on developing therapies for diseases linked to the complement system, emphasizing innovation and patient care in various medical fields.
Apellis Pharmaceuticals announced the pricing of its underwritten public offering of 8,750,000 shares at $40.00 per share, totaling $350 million in gross proceeds. The offering aims to enhance the company's financial position and support further development in targeted C3 therapies. A 30-day option for underwriters to purchase an additional 1,312,500 shares is also available. The offering is set to close on November 18, 2021, pending customary conditions. J.P. Morgan, Goldman Sachs, and Evercore are leading the offering, emphasizing the company's focus on innovative therapeutics.