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Apellis Pharmace Stock Price, News & Analysis

APLS Nasdaq

Welcome to our dedicated page for Apellis Pharmace news (Ticker: APLS), a resource for investors and traders seeking the latest updates and insights on Apellis Pharmace stock.

Apellis Pharmaceuticals, Inc. (APLS) is a leader in developing transformative therapies targeting the complement system, with approved treatments for geographic atrophy and rare blood disorders. This page provides investors and researchers with essential updates on the company’s progress in retinal, hematologic, and renal disease innovation.

Access timely announcements including FDA decisions, clinical trial results, and strategic partnerships that demonstrate Apellis’ commitment to advancing complement immunotherapy. Our curated news collection covers critical developments such as SYFOVRE’s commercial adoption, EMPAVELI’s clinical applications, and research collaborations expanding therapeutic pipelines.

Key updates include regulatory milestones in ophthalmology, hematology treatment expansions, and nephrology research advancements. Bookmark this page to stay informed about Apellis’ pioneering work in C3-targeted therapies and its impact on addressing diseases with limited treatment options.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced its participation in two major investor conferences in December 2024. The company will present at the Evercore ISI HealthCONx Conference on December 4 at 9:10 a.m. ET and the Citi Global Healthcare Conference on December 5 at 1:00 p.m. ET. Both fireside chat sessions will be available via webcast on the company's website under the 'Events and Presentations' page, with replays accessible for approximately 90 days after the events.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced its participation in the Jefferies London Healthcare Conference. The company will host a fireside chat on Tuesday, November 19, 2024, at 8:30 a.m. GMT. The event will be accessible through a live webcast on the company's website under the 'Events and Presentations' page in the 'Investors and Media' section. Interested parties can access a replay of the webcast, which will remain available for approximately 90 days after the event.

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Apellis Pharmaceuticals reported Q3 2024 financial results with total revenue of $196.8 million, including $176.6 million in U.S. net product sales. SYFOVRE demand grew 7% quarter-over-quarter, generating $152.0 million in U.S. net product revenue, though sales were impacted by higher gross-to-net adjustments. EMPAVELI contributed $24.6 million in U.S. net product revenue. The company reported a net loss of $57.4 million and held cash and equivalents of $396.9 million as of September 30, 2024. Following FDA feedback, Apellis plans to file an sNDA for pegcetacoplan in C3G/IC-MPGN in early 2025.

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Apellis Pharmaceuticals (APLS) announced positive Phase 3 VALIANT study results for pegcetacoplan in treating C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN). The study demonstrated a statistically significant 68% proteinuria reduction compared to placebo. Key secondary endpoints showed pegcetacoplan stabilized kidney function (eGFR) with a +6.3mL/min/1.73m2 difference over placebo, and 71% of treated patients achieved complete clearance of C3c deposits. The treatment demonstrated a favorable safety profile, with similar adverse event rates between treatment and placebo groups. Apellis plans FDA submission in early 2025.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced it will host a conference call and webcast on November 5, 2024, at 8:30 a.m. ET to discuss its third quarter 2024 financial results. Interested parties can pre-register for the call, and a live audio webcast with accompanying slides will be accessible through the company's website. A replay of the webcast will be available for 90 days following the event.

Apellis is a global biopharmaceutical company focused on developing life-changing therapies for challenging diseases. They have introduced the first new class of complement medicine in 15 years and currently have two approved medicines targeting C3, including the first-ever therapy for geographic atrophy, a leading cause of blindness worldwide. The company aims to further explore the potential of targeting C3 across various retinal, rare, and neurological diseases.

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Apellis Pharmaceuticals (Nasdaq: APLS) announced that the abstract of the Phase 3 VALIANT study of pegcetacoplan in C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN) was accepted for oral presentation at the American Society of Nephrology (ASN) Kidney Week. The presentation will take place on October 26 at 11:00 a.m. PT in San Diego, CA.

Following the presentation, Apellis will host a webinar at 12:30 p.m. PT to discuss the detailed VALIANT results. Two additional abstracts on pegcetacoplan in C3G and primary IC-MPGN were accepted as poster presentations, focusing on post-transplant recurrent cases and long-term safety and efficacy.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced the approval of equity awards for one new employee, effective October 1, 2024. These awards, granted outside the company's 2017 Stock Incentive Plan but under the 2020 Inducement Stock Incentive Plan, are in compliance with Nasdaq Listing Rule 5635(c)(4). The employee received 4,240 restricted stock units (RSUs). The vesting schedule for these RSUs is as follows:

  • 25% of the shares will vest on the first anniversary of the grant date
  • An additional 25% will vest annually thereafter

Vesting is subject to the employee's continued employment on each vesting date. These equity awards are considered material to the employee's acceptance of employment with Apellis Pharmaceuticals.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced its participation in the UBS Virtual Ophthalmology Day. The company will host a fireside chat on Wednesday, October 2, 2024, at 8:30 a.m. ET. This event will be accessible through a live webcast on the company's website, specifically on the "Events and Presentations" page within the "Investors and Media" section.

For those unable to attend the live event, Apellis will provide a replay of the webcast, which will remain available for approximately 90 days following the event. This virtual participation underscores Apellis' commitment to engaging with investors and industry professionals in the ophthalmology sector.

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Apellis Pharmaceuticals announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has confirmed its negative opinion on the marketing authorization application of intravitreal pegcetacoplan for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration in the EU.

The company expressed disappointment with the decision, which leaves millions of Europeans with GA without a treatment option. Despite support from the European retina community and dissenting votes from some CHMP members, the negative opinion was upheld. Apellis remains committed to expanding access to pegcetacoplan in other regions globally, focusing on unmet patient needs in the U.S. and elsewhere.

GA is an advanced form of age-related macular degeneration and a leading cause of blindness worldwide, affecting over five million people globally. Pegcetacoplan is approved in the United States under the brand name SYFOVRE® for the treatment of GA secondary to age-related macular degeneration.

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Apellis Pharmaceuticals (Nasdaq: APLS) has announced the approval of equity inducement awards for one new employee, effective September 3, 2024. The grants, made outside the company's 2017 Stock Incentive Plan but under the 2020 Inducement Stock Incentive Plan, comply with Nasdaq Listing Rule 5635(c)(4). The employee received 1,015 restricted stock units (RSUs). These RSUs will vest over four years, with 25% vesting on the first anniversary of the grant date and an additional 25% annually thereafter, contingent on continued employment.

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FAQ

What is the current stock price of Apellis Pharmace (APLS)?

The current stock price of Apellis Pharmace (APLS) is $17.82 as of July 2, 2025.

What is the market cap of Apellis Pharmace (APLS)?

The market cap of Apellis Pharmace (APLS) is approximately 2.3B.
Apellis Pharmace

Nasdaq:APLS

APLS Rankings

APLS Stock Data

2.31B
106.55M
13.86%
103.5%
16.58%
Biotechnology
Pharmaceutical Preparations
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United States
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