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Apimeds Pharmaceuticals US, Inc. Announces Closing of Initial Public Offering

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Apimeds Pharmaceuticals US (NYSE American: APUS) has successfully completed its Initial Public Offering (IPO), raising $13.5 million in gross proceeds through the sale of 3,375,000 common stock shares at $4.00 per share. The company's shares began trading on NYSE American under the symbol "APUS" on May 9, 2025.

The clinical-stage biopharmaceutical company is developing Apitox, an intradermally administered bee venom-based toxin with potential therapeutic applications. The IPO proceeds will fund a Phase III clinical trial in knee osteoarthritis, initiate corporate sponsorship studies in multiple sclerosis, support product manufacturing, and address working capital needs.

D. Boral Capital served as the sole book-running manager, with underwriters receiving a 45-day option to purchase up to 506,250 additional shares and warrants for up to 168,750 shares.

Apimeds Pharmaceuticals US (NYSE American: APUS) ha completato con successo la sua Offerta Pubblica Iniziale (IPO), raccogliendo 13,5 milioni di dollari di proventi lordi tramite la vendita di 3.375.000 azioni ordinarie a 4,00 dollari per azione. Le azioni della società hanno iniziato a essere negoziate sul NYSE American con il simbolo "APUS" il 9 maggio 2025.

La società biofarmaceutica in fase clinica sta sviluppando Apitox, una tossina a base di veleno d'ape somministrata per via intradermica con potenziali applicazioni terapeutiche. I proventi dell'IPO finanzieranno uno studio clinico di Fase III sull'osteoartrite del ginocchio, avvieranno studi di sponsorizzazione aziendale sulla sclerosi multipla, sosterranno la produzione del prodotto e copriranno le esigenze di capitale circolante.

D. Boral Capital ha agito come unico gestore del libro ordini, con sottoscrittori che hanno ricevuto un'opzione di 45 giorni per acquistare fino a 506.250 azioni aggiuntive e warrant per un massimo di 168.750 azioni.

Apimeds Pharmaceuticals US (NYSE American: APUS) ha completado con éxito su Oferta Pública Inicial (IPO), recaudando 13,5 millones de dólares en ingresos brutos mediante la venta de 3.375.000 acciones ordinarias a 4,00 dólares por acción. Las acciones de la compañía comenzaron a cotizar en NYSE American bajo el símbolo "APUS" el 9 de mayo de 2025.

La empresa biofarmacéutica en etapa clínica está desarrollando Apitox, una toxina a base de veneno de abeja administrada por vía intradérmica con aplicaciones terapéuticas potenciales. Los ingresos de la IPO financiarán un ensayo clínico de Fase III en osteoartritis de rodilla, iniciarán estudios de patrocinio corporativo en esclerosis múltiple, apoyarán la fabricación del producto y cubrirán necesidades de capital de trabajo.

D. Boral Capital actuó como único administrador del libro, con los suscriptores recibiendo una opción de 45 días para comprar hasta 506.250 acciones adicionales y warrants por hasta 168.750 acciones.

Apimeds Pharmaceuticals US (NYSE American: APUS)는 기업공개(IPO)를 성공적으로 마무리하여, 보통주 3,375,000주를 주당 4.00달러에 판매해 총 1,350만 달러의 총수익을 확보했습니다. 회사 주식은 2025년 5월 9일부터 NYSE American에서 "APUS"라는 심볼로 거래를 시작했습니다.

임상 단계의 바이오제약 회사인 이 기업은 잠재적 치료 적용이 가능한 꿀벌 독 기반 독소인 Apitox을 피내 투여 방식으로 개발 중입니다. IPO 수익금은 무릎 골관절염에 대한 3상 임상시험 자금, 다발성 경화증에 대한 기업 후원 연구 시작, 제품 제조 지원 및 운전자본 확보에 사용될 예정입니다.

D. Boral Capital이 단독 주관사로 활동했으며, 인수인들은 45일 동안 최대 506,250주 추가 매입 옵션과 최대 168,750주에 대한 워런트를 받았습니다.

Apimeds Pharmaceuticals US (NYSE American : APUS) a réussi son offre publique initiale (IPO), levant 13,5 millions de dollars de recettes brutes grâce à la vente de 3 375 000 actions ordinaires à 4,00 dollars par action. Les actions de la société ont commencé à être négociées sur le NYSE American sous le symbole « APUS » le 9 mai 2025.

Cette société biopharmaceutique en phase clinique développe Apitox, une toxine à base de venin d'abeille administrée par voie intradermique avec des applications thérapeutiques potentielles. Les fonds de l’IPO financeront un essai clinique de phase III sur l’arthrose du genou, lanceront des études de parrainage d’entreprise en sclérose en plaques, soutiendront la fabrication du produit et répondront aux besoins en fonds de roulement.

D. Boral Capital a agi en tant que gestionnaire unique du livre, les souscripteurs disposant d’une option de 45 jours pour acheter jusqu’à 506 250 actions supplémentaires et des bons de souscription portant sur jusqu’à 168 750 actions.

Apimeds Pharmaceuticals US (NYSE American: APUS) hat erfolgreich seinen Börsengang (IPO) abgeschlossen und dabei 13,5 Millionen US-Dollar Bruttoerlös durch den Verkauf von 3.375.000 Stammaktien zu je 4,00 US-Dollar pro Aktie erzielt. Die Aktien des Unternehmens wurden am 9. Mai 2025 unter dem Symbol "APUS" an der NYSE American zum Handel zugelassen.

Das biopharmazeutische Unternehmen in der klinischen Entwicklungsphase entwickelt Apitox, ein intradermal verabreichtes Bienengift-basiertes Toxin mit potenziellen therapeutischen Anwendungen. Die Erlöse aus dem IPO werden eine Phase-III-Studie bei Kniearthrose finanzieren, Unternehmenssponsorings bei Multipler Sklerose initiieren, die Produktfertigung unterstützen und den Betriebskapitalbedarf decken.

D. Boral Capital fungierte als alleiniger Buchführer, wobei die Underwriter eine 45-tägige Option erhielten, bis zu 506.250 zusätzliche Aktien und Warrants für bis zu 168.750 Aktien zu erwerben.

Positive
  • Successfully raised $13.5 million in gross proceeds through IPO
  • Phase III clinical trial stage indicates advanced development progress
  • Diverse therapeutic applications potential across multiple conditions
  • Clear allocation of funds for clinical trials and product manufacturing
Negative
  • Potential dilution from additional share options granted to underwriters
  • Early-stage company with no approved products yet
  • Significant capital requirements for clinical trials and manufacturing
  • Competition in both osteoarthritis and multiple sclerosis markets

Insights

Apimeds has successfully raised $13.5M via IPO at $4/share to fund critical Phase III trials for bee venom-based therapeutics.

Apimeds Pharmaceuticals has completed its initial public offering, raising $13.5 million in gross proceeds through the sale of 3,375,000 shares at $4.00 per share. The IPO represents a modest capital raise relative to typical biopharma offerings, reflecting the early-stage nature of the company's pipeline. Their shares began trading on the NYSE American exchange on May 9 under the ticker "APUS".

The IPO structure includes additional provisions that could increase capital: underwriters have a 45-day option to purchase an additional 506,250 shares, potentially increasing proceeds by approximately $2 million. The company also issued warrants to underwriters for up to 168,750 shares (or 194,063 if over-allotment exercised), exercisable after a 180-day lockup period.

The proceeds have clearly designated purposes, with the capital primarily allocated to fund a critical Phase III trial for knee osteoarthritis, initiate corporate sponsorship studies for multiple sclerosis applications, expand manufacturing capacity, and address working capital needs. This financing should provide Apimeds with runway to reach significant clinical milestones.

Notably, the company's lead candidate Apitox, an intradermally-administered bee venom-based toxin, represents an interesting therapeutic approach that could potentially address multiple indications. The advancement to Phase III trials for osteoarthritis suggests promising earlier clinical results, though investors should recognize that even with successful Phase III trials, commercialization remains distant and would require substantial additional capital beyond this initial raise.

Hopewell, New Jersey, May 12, 2025 (GLOBE NEWSWIRE) -- Apimeds Pharmaceuticals US, Inc. (NYSE American: APUS) (“Apimeds” or the “Company”), a clinical stage biopharmaceutical company that is in the process of developing Apitox, an intradermally administered bee venom-based toxin which potentially exhibits diverse therapeutic effects, today announced the closing of its initial public offering (the “Offering”) of 3,375,000 shares of common stock at a public offering price of $4.00 per share. The shares began trading on the NYSE American on May 9, 2025, under the symbol “APUS.” 

Gross proceeds to Apimeds from the Offering were $13.5 million, before deducting underwriting discounts and commissions and other related expenses payable by the Company. In addition, the Company has granted the underwriters a 45-day option from the closing of the Offering to purchase up to an additional 506,250 shares of common stock at the public offering price, less underwriting discounts, and issued to the underwriters warrants to purchase up to a total of 168,750 shares of common stock (or 194,063 shares if the over-allotment option is exercised in full) exercisable during the four and a half-year period commencing 180 days from the closing of the Offering.

D. Boral Capital LLC  (“D. Boral”) acted as sole book-running manager for the Offering. D. Boral was represented by Blank Rome LLP, led by Brad Shiffman and Naomi Gallimore. Apimeds was represented by Nelson Mullins Riley & Scarborough LLP, led by David Mannheim, Mike Bradshaw and Kathryn Simons. 

The Company expects to use the net proceeds from the sale of the shares to fund a Phase III clinical trial in knee osteoarthritis, to initiate at least one non-registered corporate sponsorship study in multiple sclerosis, to manufacture its product candidate, and to address general working capital needs.

A registration statement on Form S-1 (File No. 333-282324) relating to the securities sold in the Offering was filed with the U.S. Securities and Exchange Commission (the “SEC”) and was declared effective on February 11, 2025. A post-effective amendment to the registration statement was filed with the SEC and declared effective on May 5, 2025. This Offering was made only by means of a prospectus. Copies of the final prospectus relating to the Offering may be obtained, when available, from: D. Boral Capital LLC, 590 Madison Ave., 39th Floor, New York, NY 10022, by telephone: (212) 970-5150, or by email at: info@dboralcapital.com

This press release does not constitute an offer to sell, or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.

About Apimeds Pharmaceuticals US, Inc.

Apimeds (NYSE American: APUS) is a clinical stage biopharmaceutical company that is in the process of developing Apitox, an intradermally administered bee venom-based toxin which potentially exhibits diverse therapeutic effects. Apimeds is currently developing Apitox as a potential osteoarthritis treatment for patients with knee pain who fail to respond adequately to conservative non-pharmacologic therapy and simple analgesics. For more information visit www.apimedsus.com.

Forward-Looking Statements

This press release contains statements that constitute “forward-looking statements,” with respect to the anticipated use of the net proceeds. No assurance can be given that the net proceeds of the Offering will be used as indicated. All statements other than statements of historical facts are forward-looking statements. You can identify these forward-looking statements by words or phrases such as “may,” “will,” “expect,” “anticipate,” “aim,” “estimate,” “intend,” “plan,” “believe,” “likely to” or other similar expressions. The Company has based these forward-looking statements largely on its current expectations and projections about future events that it believes may affect its financial condition, results of operations, business strategy and financial needs. These statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements to be materially different from those expressed or implied by the forward-looking statements. These risks and uncertainties include forward-looking statements include, but are not limited to, the risks and uncertainties described in “Special Note Regarding Forward-Looking Statements,” “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and the documents that referred to in the prospectus filed with the SEC with the understanding that the Company’s future results may be materially different from and worse than what we expect. Copies are available on the SEC’s website, www.sec.gov. Other sections of the prospectus include additional factors which could adversely impact the Company’s business and financial performance. Moreover, the Company operates in an evolving environment. New risk factors and uncertainties emerge from time to time and it is not possible for the Company’s management to predict all risk factors and uncertainties, nor can the Company assess the impact of all factors on its business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. The Company and the underwriters qualify all of the forward-looking statements by these cautionary statements. 

You should not rely upon forward-looking statements as predictions of future events. The forward-looking statements made in the prospectus relate only to events or information as of the date on which the statements are made in the prospectus. Neither the Company nor the underwriters undertake any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events except as required by law. You should read the prospectus and the documents that we refer to in the prospectus and have filed as exhibits to the registration statement, of which the prospectus is a part, completely and with the understanding that our actual future results may be materially different from what we expect.

Contact:

Erik Emerson
Apimeds Pharmaceuticals US, Inc.
(808) 209-7887


FAQ

How much did Apimeds Pharmaceuticals (APUS) raise in its IPO?

Apimeds Pharmaceuticals raised $13.5 million in gross proceeds through its IPO by selling 3,375,000 shares at $4.00 per share.

What is APUS stock's main product candidate?

Apimeds' main product candidate is Apitox, an intradermally administered bee venom-based toxin being developed for therapeutic applications.

What will Apimeds (APUS) use its IPO proceeds for?

The proceeds will fund a Phase III trial in knee osteoarthritis, initiate multiple sclerosis studies, support product manufacturing, and address working capital needs.

When did APUS stock begin trading on NYSE American?

APUS shares began trading on the NYSE American on May 9, 2025.

What is the over-allotment option in Apimeds' IPO?

Underwriters received a 45-day option to purchase up to 506,250 additional shares at the public offering price, less underwriting discounts.
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