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Ardelyx to Report Full Year and Fourth Quarter 2025 Financial Results on February 19, 2026

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Ardelyx (Nasdaq: ARDX) will report full year and fourth quarter 2025 results and host a conference call on Thursday, February 19, 2026 at 4:30 p.m. Eastern Time. The call will feature the executive leadership team and include a business update.

Live audio will be webcast via the Investors section at the company's website and archived for replay for 30 days.

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Positive

  • None.

Negative

  • None.

Key Figures

2025 product revenue: $378 million IBSRELA 2025 revenue: $274 million IBSRELA Q4 2025: $87 million +5 more
8 metrics
2025 product revenue $378 million Preliminary unaudited 2025 product revenue
IBSRELA 2025 revenue $274 million IBSRELA 2025 revenue, 73% increase vs. 2024
IBSRELA Q4 2025 $87 million Q4 2025 IBSRELA revenue
XPHOZAH 2025 revenue $104 million XPHOZAH full-year 2025 revenue
XPHOZAH Q4 2025 $28 million Q4 2025 XPHOZAH revenue
Year-end 2025 cash $265 million Cash, cash equivalents and investments at end of 2025
2026 IBSRELA guidance $410–430 million Expected 2026 IBSRELA revenue
2026 XPHOZAH guidance $110–120 million Expected 2026 XPHOZAH revenue

Market Reality Check

Price: $7.38 Vol: Volume 2,711,573 vs 20-da...
low vol
$7.38 Last Close
Volume Volume 2,711,573 vs 20-day average 5,989,692 (relative volume 0.45) low
Technical Price 7.38 trading above 200-day MA at 5.34 before this announcement

Peers on Argus

Ahead of the earnings date call, ARDX was down 4.65%. Key biotech peers were mix...

Ahead of the earnings date call, ARDX was down 4.65%. Key biotech peers were mixed: AUPH -4.08%, MNKD -7.52%, VERA -4.77%, VCEL -0.73%, while CDTX was roughly flat at +0.03%. No peers appeared in the momentum scanner and there were no same-day peer headlines, indicating the move looked more stock-specific than part of a broad sector rotation.

Historical Context

5 past events · Latest: Feb 03 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Feb 03 Patent issuance Positive -0.6% USPTO issued new tenapanor formulation patent expiring November 26, 2042.
Jan 28 Phase 3 trial start Positive -0.4% First patient dosed in ACCEL Phase 3 CIC study of IBSRELA (tenapanor).
Jan 08 Prelim 2025 revenue Positive +20.1% Preliminary 2025 revenue, strong IBSRELA growth and 2026 guidance outlined.
Nov 07 Real-world data Positive +1.1% Real-world XPHOZAH data showed phosphate reductions and patient satisfaction.
Nov 05 Conference participation Positive +6.3% Management participation in Jefferies Global Healthcare Conference fireside chat.
Pattern Detected

Recent fundamentally positive milestones have often seen mixed price reactions, with strong gains on revenue/guidance news but occasional small declines on positive patent and clinical updates.

Recent Company History

In the last few months, Ardelyx reported several meaningful developments before scheduling its February 19, 2026 earnings call. A January update outlined preliminary 2025 product revenue of about $378 million, strong growth for IBSRELA and XPHOZAH, and detailed 2026 revenue guidance, which coincided with a 20.07% gain. Earlier, the company initiated the Phase 3 ACCEL trial in chronic idiopathic constipation and secured a new U.S. patent for tenapanor formulations, both followed by modest share declines. Real-world XPHOZAH data and a Jefferies conference appearance produced smaller positive moves, showing a mixed but generally constructive reaction pattern.

Market Pulse Summary

This announcement schedules Ardelyx’s full-year and fourth-quarter 2025 results call for February 19...
Analysis

This announcement schedules Ardelyx’s full-year and fourth-quarter 2025 results call for February 19, 2026, following earlier disclosure of preliminary $378 million 2025 product revenue and detailed 2026 guidance for IBSRELA and XPHOZAH. Recent milestones include a new U.S. patent for tenapanor formulations and initiation of the ACCEL Phase 3 CIC study. Investors may focus on how final results compare with the preliminary figures and whether management updates its longer-term revenue outlook.

AI-generated analysis. Not financial advice.

Conference call scheduled for 4:30 p.m. Eastern Time

WALTHAM, Mass., Feb. 05, 2026 (GLOBE NEWSWIRE) -- Ardelyx, Inc. (Nasdaq: ARDX), a biopharmaceutical company founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs, today announced it will hold a conference call on Thursday, February 19, 2026, at 4:30 p.m. Eastern Time to discuss financial results and provide a business update from the full year and fourth quarter of 2025. The call will include commentary from members of the Ardelyx Executive Leadership Team including Mike Raab, President and Chief Executive Officer, Sue Hohenleitner, Chief Financial Officer, Eric Foster, Chief Commercial Officer, and Laura Williams M.D., M.P.H., Chief Patient Officer and Interim Chief Medical Officer.

To participate in the conference call, please dial (877) 346-6112 (domestic) or (848) 280-6350 (international) and ask to be joined into the Ardelyx call. Live audio of the conference call will be simultaneously webcast and will be available under the Investors section of the company's website at www.ardelyx.com. The webcast will be archived and available for replay for 30 days following the call.

About Ardelyx
Ardelyx was founded with a mission to discover, develop and commercialize innovative, first-in-class medicines that meet significant unmet medical needs. Ardelyx has two commercial products approved in the United States, IBSRELA® (tenapanor) and XPHOZAH® (tenapanor). The company’s pipeline includes the Phase 3 development of IBSRELA for chronic idiopathic constipation (CIC) and RDX10531, a next-generation NHE3 inhibitor with potential application across multiple therapeutic areas. Ardelyx has agreements for the development and commercialization of tenapanor outside of the U.S. Kyowa Kirin commercializes PHOZEVEL® (tenapanor) for hyperphosphatemia in Japan. A New Drug Application for tenapanor for hyperphosphatemia has been approved in China with Fosun Pharma. Knight Therapeutics commercializes IBSRELA in Canada. For more information, please visit https://ardelyx.com/ and connect with us on X (formerly known as Twitter), LinkedIn and Facebook.

Investor and Media Contacts:
Caitlin Lowie
clowie@ardelyx.com


FAQ

When will Ardelyx (ARDX) report full year and Q4 2025 financial results?

Ardelyx will report results on February 19, 2026 and host a call at 4:30 p.m. ET. According to Ardelyx, the call covers full year and fourth quarter 2025 financial results and a business update from company leadership.

How can investors join the Ardelyx (ARDX) conference call on February 19, 2026?

Dial (877) 346-6112 (domestic) or (848) 280-6350 (international) and request the Ardelyx call. According to Ardelyx, the live audio will also be simultaneously webcast on the Investors section of the company's website for remote access.

Who will speak on the Ardelyx (ARDX) February 19, 2026 earnings call?

Speakers include CEO Mike Raab, CFO Sue Hohenleitner, CCO Eric Foster, and Chief Patient Officer and Interim CMO Laura Williams M.D., M.P.H. According to Ardelyx, members of the executive leadership team will provide commentary and a business update.

Where will the Ardelyx (ARDX) webcast be available and how long will the replay last?

The live webcast will be available under the Investors section at www.ardelyx.com and archived for replay. According to Ardelyx, the webcast replay will remain accessible for 30 days following the February 19, 2026 call.

What topics will Ardelyx (ARDX) cover during the February 19, 2026 call?

The call will discuss full year and fourth quarter 2025 financial results and provide a business update from leadership. According to Ardelyx, the management team will offer commentary on company performance and operational highlights for investors.
Ardelyx

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1.88B
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Biotechnology
Pharmaceutical Preparations
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United States
FREMONT