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Armata Pharmaceuticals develops pathogen-specific bacteriophage therapeutics for antibiotic-resistant and difficult-to-treat bacterial infections. News about ARMP centers on its late clinical-stage phage pipeline, including AP-SA02 for Staphylococcus aureus bacteremia and AP-PA02 for Pseudomonas aeruginosa, FDA designations and regulatory interactions, scientific publications on phage structure, and clinical program updates.
Company updates also cover financial results, research and development spending, grant-supported program activity, credit agreement and warrant amendments with Innoviva-related entities, and board or annual-meeting governance matters. Armata describes in-house phage-specific cGMP manufacturing as part of its development model.
Armata Pharmaceuticals (NYSE: ARMP) announced the appointment of Mina Pastagia, MD, MS, as Vice President of Clinical Development. This strategic move comes as Armata prepares to advance two therapeutic candidates: AP-PA02 for Pseudomonas aeruginosa infections and AP-SA02 for Staphylococcus aureus bacteremia. Dr. Pastagia's extensive expertise in anti-infective drug development will enhance Armata's pipeline capabilities. The company has also granted her equity awards as part of the employment agreement.
Armata Pharmaceuticals (NYSE American: ARMP) announced FDA clearance of its IND application to initiate a Phase 1b/2a clinical trial for its candidate AP-PA02 targeting Pseudomonas aeruginosa infections. This trial, named SWARM-P.a., will evaluate the safety of inhaled AP-PA02 in cystic fibrosis patients with chronic infections. The company aims to commence the study by the end of 2020, despite COVID-19 disruptions. Armata seeks to develop phage-based therapies as alternatives to traditional antibiotics, supported by a $15 million grant from the CF Foundation.
Armata Pharmaceuticals (NYSE American: ARMP) announced that President Brian Varnum will present at the 2020 World Antimicrobial Resistance Congress on October 8 at 12:10 pm EDT. The presentation, titled "Development of Phage Therapeutics Targeting Pseudomonas aeruginosa and Staphylococcus aureus", will be part of the Innovation Showcase session. This event, featuring over 700 attendees and 250 speakers, is the largest commercial gathering focused on antimicrobial resistance. Armata specializes in bacteriophage therapies for antibiotic-resistant infections.
Armata Pharmaceuticals (NYSE American: ARMP) reported Q2 2020 results, highlighting a $15 million award from the U.S. Department of Defense to advance the development of AP-SA02 for Staphylococcus aureus bacteremia infections. The funding will support a Phase 1b/2 clinical trial anticipated to begin in 2021. Additionally, Armata expects to initiate a Phase 1b/2a clinical trial for AP-PA02 targeting Pseudomonas aeruginosa infections by the end of 2020. As of June 30, 2020, the company had $19.8 million in cash, sufficient to fund operations through at least mid-2021.
Armata Pharmaceuticals (NYSE American: ARMP) announced a $15 million award from the U.S. Department of Defense to support a Phase 1b/2 clinical study of AP-SA02, targeting S. aureus bacteremia. This funding will enhance the development of phage-based therapeutics amid rising antibiotic resistance. The study aims to assess the safety and tolerability of AP-SA02 alongside traditional antibiotic therapies. Armata's CEO stated this funding exceeds expectations and facilitates progress in addressing drug-resistant infections.