Arvinas Stock Price, News & Analysis

Arvinas, Inc. (Nasdaq: ARVN) has priced a public offering of 5,714,286 shares of its common stock at $70.00 per share, with an option for underwriters to purchase an additional 857,142 shares. This offering is expected to close around December 18, 2020, subject to standard conditions. The funds raised will support Arvinas' efforts in developing targeted protein degradation therapies through its PROTAC® platform, which focuses on treating severe diseases. Goldman Sachs and Piper Sandler are leading the underwriting process.

Arvinas, Inc. (Nasdaq: ARVN) has announced a public offering of $250 million of its common stock, with an additional $37.5 million option for underwriters. Goldman Sachs & Co. LLC and Piper Sandler & Co. are the joint book-running managers. This offering is part of a planned strategy to support Arvinas’ ongoing clinical programs, including its two key candidates: ARV-110 for prostate cancer and ARV-471 for breast cancer. The offering is subject to market conditions and investor interest.

Arvinas, a clinical-stage biopharmaceutical company, announced clinical updates on its PROTAC® protein degraders: ARV-471 and ARV-110. ARV-471 shows potential for best-in-class safety and efficacy in patients with ER+/HER2- breast cancer, demonstrated by a 42% clinical benefit rate and confirmed partial responses. ARV-110 displays anti-tumor activity in men with metastatic castration-resistant prostate cancer, achieving a 40% PSA50 response rate. Both compounds are well tolerated, with ongoing trials expected to advance in 2021, including combination studies.

Arvinas, a clinical-stage biotechnology company, will host a live webcast on December 14, 2020, at 8:00 a.m. ET to present updates on its clinical programs for ARV-471 and ARV-110. The presentation will cover the Phase 1 dose escalation studies for ARV-471 in ER positive/HER2 negative breast cancer and ARV-110 for metastatic castrate-resistant prostate cancer, along with details about the newly initiated Phase 2 dose expansion study for ARV-110.

Arvinas, a clinical-stage biotechnology company focused on targeted protein degradation, will present at two virtual investor conferences. The first is the Piper Sandler 32nd Annual Virtual Healthcare Conference on December 1, 2020, featuring a pre-recorded chat with management. The second conference is the 3rd Annual Evercore ISI HealthCONx Virtual Conference on December 3, 2020, with live participation from key executives. Arvinas is dedicated to developing therapies for debilitating diseases using its proprietary PROTAC® platform, targeting proteins causing various conditions.

Arvinas, a clinical-stage biopharmaceutical firm, announced significant updates in its latest press release. The company has initiated Phase 2 dosing for ARV-110 and continues dose escalation for ARV-110 and ARV-471 trials. A collaboration with Pfizer will lead to a Phase 1b trial combining ARV-471 with Ibrance, expected to start fourth quarter 2020. Financial results for Q3 2020 highlighted a net loss of $30.8 million, an increase from $17.7 million in Q3 2019, amid rising R&D expenses of $30.0 million. Cash reserves were $248.6 million, sufficient to support operations into 2022.

Arvinas, Inc. (Nasdaq: ARVN) announced significant updates to its preclinical pipeline, revealing five new programs targeting oncology, immuno-oncology, and neuroscience. The company aims to enhance its leadership in targeted protein degradation with its PROTAC® Discovery Engine. Key targets include BCL6, KRAS, Myc, HPK1, and mHTT, with plans to file INDs by 2022 and 2023. Clinical trials are ongoing for ARV-110 and ARV-471, with data updates expected in Q4 2020. This expansion underscores Arvinas' commitment to addressing high unmet medical needs in various disease areas.

Arvinas, a clinical-stage biotechnology company (Nasdaq: ARVN), will have its President and CEO, John Houston, Ph.D., present at the 3rd Annual Targeted Protein Degradation Summit on October 14-15, 2020. The session, titled "The Promise of PROTAC® Protein Degraders: What’s Next for Arvinas’ Pipeline & Platform," will showcase advancements in Arvinas' PROTAC® technology and introduce new pipeline programs. The company focuses on developing therapies that degrade disease-causing proteins, with two clinical-stage programs targeting advanced prostate and breast cancers.

Arvinas, a clinical-stage biotechnology company (Nasdaq: ARVN), announced that its Chief Scientific Officer, Ian Taylor, Ph.D., will participate in a fireside chat at the Citi 15th Annual BioPharma Virtual Conference on September 10 at 2:25 p.m. ET. A live audio webcast will be available here and on Arvinas’ website. The company is focused on developing therapies for diseases like metastatic prostate cancer and ER+/HER2- breast cancer.