Welcome to our dedicated page for Actinium Pharmac news (Ticker: ATNM), a resource for investors and traders seeking the latest updates and insights on Actinium Pharmac stock.
The Actinium Pharmaceuticals, Inc. (NYSE American: ATNM) news page on Stock Titan aggregates company announcements, scientific conference updates and regulatory disclosures related to its Actinium-225 targeted radiotherapy programs. Actinium regularly issues press releases detailing preclinical and clinical data, corporate events and participation in oncology meetings, offering investors and observers insight into the evolution of its pipeline.
Recent news has focused heavily on ATNM-400, the company’s first-in-class, multi-indication Ac-225 antibody radioconjugate. Actinium has reported preclinical data for ATNM-400 in metastatic castration-resistant prostate cancer, non-small cell lung cancer (NSCLC) and breast cancer, including models resistant to standard-of-care therapies such as enzalutamide, 177Lu-PSMA-617, osimertinib, tamoxifen and trastuzumab. Releases describe superior tumor growth inhibition versus several approved agents, durable tumor control, and synergistic effects when ATNM-400 is combined with ARPIs or EGFR inhibitors.
News items also cover Actimab-A, a CD33-targeting Ac-225 therapeutic for acute myeloid leukemia, including its planned pivotal Phase 2/3 trial and a Cooperative Research and Development Agreement with the National Cancer Institute. Additional updates describe Iomab-ACT and Iomab-B in conditioning for bone marrow transplant and cell or gene therapies, as well as Actinium’s broader research efforts in solid tumors.
Visitors to this page can review earnings‑independent scientific updates, conference abstracts and corporate communications that outline Actinium’s development strategy, preclinical results and governance milestones such as annual meeting outcomes. For anyone tracking ATNM as an oncology development story, this news feed provides a centralized view of how the company portrays progress across its Ac‑225 radiotherapy platform.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced positive results from the Phase 1 trial of Actimab-A combined with venetoclax for treating relapsed or refractory acute myeloid leukemia (AML). Presented at the 63rd ASH Annual Meeting, the trial showed a 67% overall response rate, including two remissions in patients with a TP53 mutation. Notably, there has been no early mortality in the study. The trial aims to finalize the dosing for the Phase 2 study, addressing the significant unmet need for patients who do not respond to existing therapies.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced positive results from the fully enrolled Phase 3 SIERRA trial of Iomab-B at the 63rd ASH Annual Meeting. Iomab-B, an antibody radiation conjugate targeting CD45, aims to facilitate bone marrow transplants for patients aged 55+ with relapsed or refractory acute myeloid leukemia (r/r AML). The trial demonstrated a significant difference, with 100% engraftment rates in the Iomab-B arm compared to only 21% in the conventional care arm. The company anticipates topline data in Q3 2022, potentially leading to a BLA filing with the FDA.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced its participation in the Targeted Radiopharmaceuticals Summit from December 7-9, 2021. The company will feature expert speakers from its R&D and Clinical Development teams in two significant panel discussions on December 9. Topics include the development of Alpha Emitting Therapies and optimizing therapeutic strategies. Actinium focuses on targeted radiotherapies, particularly its lead product, I-131 apamistamab (Iomab-B), which targets patients with acute myeloid leukemia. The firm emphasizes its proprietary AWE technology in advancing its clinical pipeline.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced significant findings at the 36th Annual Meeting of the Society for Immunotherapy for Cancer. Their data on an anti-HER2 antibody radiation conjugate (ARC) in combination with a CD47 blocking antibody showed promising results in solid tumor models. Key highlights include increased phagocytosis by 2-fold and enhanced tumor control. The findings support ongoing research into this combination therapy, aiming to improve patient outcomes. The poster is available on Actinium's website, showcasing advancements in targeted radiotherapies.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) presented data on Actimab-A, an antibody radiation conjugate, at the 36th Annual Meeting of the Society for Immunotherapy for Cancer from November 12-14, 2021. The findings demonstrated that Actimab-A, when combined with a CD47 blocking antibody, significantly increased survival in AML tumor models and enhanced cell surface calreticulin levels, potentially improving the immune response. This combination indicates promising therapeutic potential for treating acute myeloid leukemia (AML).
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) has announced the completion of patient enrollment in its Phase 1 trial of Actimab-A combined with CLAG-M chemotherapy for relapsed or refractory acute myeloid leukemia (AML) patients. The final cohort received 1.0 μCi/kg of Actimab-A. Previous cohorts showed a 100% remission rate at a lower dose. Data will be presented at the American Society of Hematology meeting in December, and the company anticipates updates on future developments by year-end.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) has announced that multiple abstracts showcasing its Iomab-B and Actimab-A clinical programs are set for presentation at the 63rd American Society of Hematology Annual Meeting in Atlanta, GA, from December 11-14, 2021. Notably, the pivotal Phase 3 SIERRA trial for Iomab-B has completed patient enrollment, with interim data to be presented at ASH. The company aims to demonstrate the efficacy of its targeted therapies in improving outcomes for patients with unmet medical needs, particularly in AML treatments.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced that two abstracts on targeted radiotherapies combined with CD47 antibody immunotherapy will be presented at the 36th Annual Meeting of the Society for Immunotherapy for Cancer (SITC 2021) from November 12-14, 2021. The titles focus on enhancing anti-tumor effects in solid tumors and acute myeloid leukemia. CEO Sandesh Seth expressed excitement about the R&D advancements and the company's efforts in the immunotherapy field. Full posters will be available on Actinium's website on November 9, 2021.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced its participation in the Cantor Fitzgerald Virtual Global Healthcare Conference from September 27 to 30, 2021. The company's presentation is scheduled for September 29 at 3:20 p.m. ET. Attendees can access the webcast via Actinium's investor relations website. Actinium focuses on developing targeted radiotherapies, particularly Antibody Radiation-Conjugates, aimed at improving treatment outcomes for cancer patients with high unmet needs. The company's lead candidate is I-131 apamistamab (Iomab-B), being studied in pivotal trials.
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