Welcome to our dedicated page for Biocryst Pharmaceuticals news (Ticker: BCRX), a resource for investors and traders seeking the latest updates and insights on Biocryst Pharmaceuticals stock.
BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) is a global biotechnology company focused on hereditary angioedema (HAE) and other rare diseases, and its news flow reflects this specialization. Company press releases frequently highlight regulatory milestones, clinical data, commercial performance, and strategic transactions related to its flagship product ORLADEYO® (berotralstat) and its broader rare disease pipeline.
Investors following BCRX news can expect regular updates on ORLADEYO, described as the first oral, once-daily plasma kallikrein inhibitor for prophylaxis to prevent HAE attacks. Recent announcements have covered U.S. Food and Drug Administration approval of an oral pellet formulation for pediatric patients aged 2 to <12 years, interim data from the APeX-P pediatric trial showing early and sustained reductions in attack rates, and presentations at major allergy and immunology congresses on the burden of HAE in children and caregivers.
BioCryst also issues news on its financial outlook and operating performance, including preliminary ORLADEYO net revenue, total revenue guidance that incorporates RAPIVAB® (peramivir injection), and non-GAAP operating expense expectations. These releases often explain how structural changes, such as the sale of the European ORLADEYO business, affect the company’s revenue mix and cost base.
Strategic and corporate developments are another major theme in BCRX news. The company has announced a definitive agreement to acquire Astria Therapeutics, Inc., with updates on regulatory clearances such as early termination of the Hart-Scott-Rodino waiting period and expected closing timelines. Additional news items include leadership changes, inducement equity grants under Nasdaq Listing Rule 5635(c)(4), and planned presentations at high-profile investor conferences.
For readers tracking BCRX, this news stream offers insight into BioCryst’s commercial execution in HAE, progress of its rare disease pipeline, evolving capital allocation, and key corporate events. Regularly reviewing these updates can help contextualize movements in BCRX stock and provide a clearer picture of the company’s strategic direction.
BioCryst Pharmaceuticals (Nasdaq: BCRX) announced its participation in the 41st Annual J.P. Morgan Healthcare Conference on January 10, 2023, at 6:00 p.m. ET in San Francisco. The event will feature a presentation from the company, and a live audio webcast will be accessible on their website. BioCryst specializes in developing oral medicines for rare diseases, including its approved product ORLADEYO (berotralstat) and RAPIVAB (peramivir injection). The company is also advancing multiple therapeutic projects, including BCX10013.
BioCryst Pharmaceuticals (BCRX) has announced the discontinuation of its development program for BCX9930 due to recent competitive data presented at the ASH annual meeting, indicating it would not be commercially viable. The focus will now shift entirely to BCX10013, an oral Factor D inhibitor showing promise in clinical trials. This strategic pivot is expected to have a positive financial impact, lowering 2022 operating expenses by about $100 million. Preliminary data on BCX10013 is anticipated in Q1 2023, as BioCryst aims to expand its complement therapeutic program.
BioCryst Pharmaceuticals (BCRX) announced the granting of stock options and restricted stock units (RSUs) to 21 newly-hired employees as an inducement for employment. This grant, effective November 30, 2022, includes options to purchase 134,600 shares at an exercise price of $13.36, equal to the stock's closing price on the grant date. The options and RSUs will vest over four years, contingent upon continued employment. BioCryst focuses on developing small-molecule medicines for rare diseases, including the approved oral treatment ORLADEYO®.
BioCryst Pharmaceuticals (Nasdaq: BCRX) will present virtually at the JMP Securities Hematology & Oncology Summit on December 7, 2022, at 11:40 a.m. ET. The presentation will be accessible via a live audio webcast on their website. The company specializes in developing oral, small-molecule medications for rare diseases, with its product ORLADEYO® (berotralstat) already approved in the U.S. BioCryst also has ongoing clinical programs for oral factor D inhibitors BCX9930 and BCX10013.
BioCryst Pharmaceuticals (BCRX) announced the Israeli Ministry of Health has granted marketing authorization for ORLADEYO® (berotralstat), a once-daily oral therapy for preventing hereditary angioedema (HAE) attacks in patients aged 12 and older. The company plans to partner with Neopharm for its launch in Israel. Clinical trials indicate ORLADEYO was safe and well tolerated, though gastrointestinal reactions were reported, typically resolving over time. This authorization marks a significant stride for HAE patients in Israel, providing a less burdensome treatment option.
BioCryst Pharmaceuticals (BCRX) unveiled new real-world data indicating that patients aged 12 and older using ORLADEYO (berotralstat) for hereditary angioedema (HAE) experience rapid and sustained reductions in attack rates. Presented at the 2022 ACAAI Annual Meeting, the data highlight significant efficacy improvements post-switch from other therapies, with an average attack rate reduction of 80% within the first 90 days. The results suggest ORLADEYO is effective regardless of prior treatment history, with lower adverse event rates compared to clinical trials.
BioCryst Pharmaceuticals (BCRX) announced its participation in several investor conferences. The company will present at the Jefferies London Healthcare Conference on November 16, 2022, at 12:00 p.m. ET. Additionally, BioCryst will take part in the virtual 5th Annual Evercore ISI HealthCONx Conference on November 29, 2022, at 8:25 a.m. ET, followed by the Piper Sandler 34th Annual Healthcare Conference in New York on November 30, 2022, at 8:30 a.m. ET. Live audio webcasts will be available on BioCryst's website, ensuring stakeholders can follow the updates easily.
BioCryst Pharmaceuticals (BCRX) announced that its compensation committee granted stock options and restricted stock units (RSUs) to 14 new employees as of October 31, 2022. The stock options total 125,700 shares with an exercise price of $13.35, equal to the grant date's closing stock price. The RSUs cover 46,350 shares and both vest over four years, contingent on continued employment. This action complies with Nasdaq Listing Rule 5635(c)(4) and aims to attract talent to support the company's growth in developing oral medicines for rare diseases.
BioCryst Pharmaceuticals reported Q3 2022 revenues of $75.8 million, a 85% year-over-year increase, driven mainly by $66.0 million from ORLADEYO. The patient base for ORLADEYO grew by 9% in Q3. The company is advancing its pipeline with new Factor D inhibitors, BCX10013 entering clinical trials, while screening for BCX9930 continues, with data expected mid-2023. The company anticipates full-year ORLADEYO revenue of $255 million and operating expenses between $365 million and $370 million.
BioCryst Pharmaceuticals (BCRX) announced presentations at the American College of Allergy, Asthma & Immunology's meeting from November 10-14, 2022, in Louisville, Kentucky. They will showcase two abstracts on ORLADEYO® (berotralstat) for hereditary angioedema treatment. Dr. Ryan Arnold emphasized ORLADEYO's effectiveness in reducing attack rates, making it a convenient option. The Distinguished Industry Oral Presentation will discuss real-world outcomes of berotralstat, while a poster will highlight consistently low attack rates irrespective of prior therapies.