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INSTINCT BIO Provides Operational Update on Indonesia Growth Platform and Product Development Initiatives

Instinct Bio outlines progress on its first GENRÊVER clinic in Jakarta and 2026-targeted GENRÊVER and HAKUA cosmetic product launches with partners.

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Instinct Bio (BIOT) issued an operational update on its GENRÊVER CLINIC platform in Indonesia and related cosmetic product collaborations.

The company has secured a 213 m² premises in South Jakarta’s Gandaria district for its first GENRÊVER clinic, with interior construction underway and a targeted opening by the end of December 2026, subject to construction progress, permitting and operational readiness. Preliminary monthly subscription tiers for the Jakarta clinic have been set at US$400, US$1,000 and US$3,000 per customer, with access dependent on membership terms, physician assessment, capacity and regulation.

Instinct Bio and Invitrx have identified an initial GENRÊVER-branded cosmetic product line for potential manufacture in the United States, targeted to commence within 2026. With Parva Candela, two initial cosmetic products for Indonesia under the GENRÊVER and HAKUA brands—a premium UV cream and a moisturizing gel using HA4 low-molecular-weight hyaluronic acid technology—are also targeted to enter production within 2026, subject to development, regulatory and manufacturing conditions.

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Positive

  • First GENRÊVER clinic site secured with a 213 m² premises in Gandaria, South Jakarta, interior construction started and opening targeted by end-December 2026.
  • Preliminary subscription pricing for the Jakarta GENRÊVER clinic set at monthly tiers of US$400, US$1,000 and US$3,000 per customer.
  • 2026-targeted cosmetic product launches with Invitrx and Parva Candela, including GENRÊVER-branded products and GENRÊVER/HAKUA lines for the Indonesian market.

Negative

  • None.

Market Context

BIOT’s August 10 partnership announcement was followed by a 0.1% 24-hour move, providing a compariso...
Analysis

BIOT’s August 10 partnership announcement was followed by a 0.1% 24-hour move, providing a comparison for this operational update. The current milestones remain conditional, with permitting, regulatory compliance, and manufacturing readiness as key risks to monitor.

Key Figures

Clinic premises: 213 m² Target clinic opening: End of December 2026 Subscription pricing tier: US$400 per month +5 more
8 metrics
Clinic premises 213 m² First planned GENRÊVER CLINIC site in South Jakarta
Target clinic opening End of December 2026 Subject to construction, permitting, and operational readiness
Subscription pricing tier US$400 per month Jakarta clinic preliminary pricing
Subscription pricing tier US$1,000 per month Jakarta clinic preliminary pricing
Subscription pricing tier US$3,000 per month Jakarta clinic preliminary pricing
U.S. product line Within 2026 Targeted commencement of GENRÊVER-branded cosmetic manufacturing
Indonesian product candidates Two candidates Premium UV cream and moisturizing gel
Indonesian production target Within 2026 Subject to product development, regulatory compliance, and manufacturing readiness

Historical Context

2 past events · Latest: Aug 10 (Positive)
Pattern 2 events
Date Event Sentiment 24h Move Catalyst
Aug 10 Indonesia cosmetics partnership Positive +0.1% Collaboration targeted Indonesian cosmetics development and distribution through local manufacturing partners.
Jul 29 Indonesia clinic launch Positive -57.9% Subscription beauty clinic rollout was followed by a negative 24-hour price reaction.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

BIOT diverged sharply after the July 29 clinic announcement but aligned modestly after the August 10 partnership announcement.

Key Terms

low-molecular-weight hyaluronic acid technology
1 terms
low-molecular-weight hyaluronic acid technology technical
"a moisturizing gel incorporating HA4 low-molecular-weight hyaluronic acid technology."
A formulation approach that uses hyaluronic acid molecules broken into smaller chains so they penetrate tissues or interact with cells differently than larger molecules. Investors care because this technical choice can affect a product’s effectiveness, manufacturing complexity, clinical testing needs, regulatory classification, and customer appeal—similar to how changing a recipe alters taste, shelf life, and cost in a consumer product.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Follow-up to the Company’s July 29, July 30 and August 10, 2026 announcements

NEW YORK and TOKYO, Sept. 04, 2026 (GLOBE NEWSWIRE) -- INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC. (Nasdaq: BIOT) (“Instinct Bio” or the “Company”) today provided an operational update on the initiatives previously announced on July 29, July 30 and August 10, 2026, relating to its GENRÊVER CLINIC platform in Indonesia and its product development collaborations with Invitrx Therapeutics, Inc. (“INVITRX”) and PT PARVA CANDELA (“PARVA”).

Operational Highlights

  • The Company has secured a 213 m² premises in the Gandaria district of South Jakarta for its first planned GENRÊVER CLINIC site, and interior construction activities have commenced. Subject to construction progress, permitting, and operational readiness, the Company is targeting an opening by the end of December 2026.
  • The Company has finalized preliminary subscription pricing tiers for the Jakarta clinic at monthly rates of US$400, US$1,000 and US$3,000 per customer. Treatment availability will be subject to membership terms, physician assessment, scheduling capacity, and applicable regulatory requirements.
  • The Company and INVITRX have identified an initial GENRÊVER-branded cosmetic product line-up for potential manufacture in the United States, currently targeted to commence within 2026, subject to final formulation, manufacturing scheduling, regulatory considerations, and related commercial arrangements.
  • The Company and PARVA have identified two initial cosmetic product candidates for the Indonesian market under the GENRÊVER and HAKUA brands — a premium UV cream and a moisturizing gel incorporating HA4 low-molecular-weight hyaluronic acid technology. Production is targeted to commence within 2026, subject to product development completion, regulatory compliance, and manufacturing readiness.

Additional Information. Further detail regarding the GENRÊVER CLINIC site and subscription structure, the product candidates described above, and the full text of the underlying announcements is available in the News & IR section of the Company’s website at https://instinct-biot.com/news.

Management Commentary

Tomoki Nagano, Chief Executive Officer of Instinct Bio, stated: “During the past several weeks, we have progressed site development activities in Jakarta and continued product planning discussions with our manufacturing collaborators in the United States and Indonesia.”

About Instinct Bio

INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC. (Nasdaq: BIOT) is a biotechnology company focused on regenerative medicine, wellness-related technologies, and therapeutic platform development. Website: https://instinct-biot.com/

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding the anticipated opening and operation of the Jakarta clinic, expected subscription offerings, product development activities, potential manufacturing timelines, and the Company’s collaborations with INVITRX and PARVA. These statements are based on current expectations and are subject to risks and uncertainties, many beyond the Company’s control, including construction delays, permitting and regulatory developments, product development outcomes, manufacturing and supply chain constraints, market conditions, the negotiation of definitive agreements, customer acceptance, and other risks described in the Company’s filings with the U.S. Securities and Exchange Commission. Actual results may differ materially, and readers are cautioned not to place undue reliance on these statements, which speak only as of the date hereof. Except as required by applicable law, the Company undertakes no obligation to update them.

Contact Information

INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC.
Email: ir@instinct-bro.com
Website: https://instinct-biot.com/


FAQ

What operational update did Instinct Bio (BIOT) provide on its GENRÊVER clinic in Jakarta?

Instinct Bio reported it has secured a 213 m² premises in the Gandaria district of South Jakarta for its first GENRÊVER clinic. Interior construction has begun, and the opening is targeted by the end of December 2026, subject to construction progress, permitting and operational readiness.

When is Instinct Bio (BIOT) targeting to open its first GENRÊVER clinic in Indonesia?

The company is targeting an opening for its first GENRÊVER clinic in South Jakarta by the end of December 2026. This timeline depends on construction progress, successful permitting and overall operational readiness before the clinic can begin serving customers.

What are the subscription pricing tiers for Instinct Bio's Jakarta GENRÊVER clinic (BIOT)?

Preliminary subscription pricing tiers for the Jakarta GENRÊVER clinic are set at US$400, US$1,000 and US$3,000 per month per customer. Treatment availability will depend on membership terms, physician assessment, scheduling capacity and compliance with applicable regulatory requirements.

What product collaboration did Instinct Bio (BIOT) announce with Invitrx Therapeutics?

Instinct Bio and Invitrx Therapeutics have identified an initial GENRÊVER-branded cosmetic product line-up for potential manufacture in the United States. Production is currently targeted to commence within 2026, subject to final product formulation, manufacturing scheduling, regulatory considerations and related commercial arrangements.

Which cosmetic products is Instinct Bio (BIOT) developing with PT Parva Candela for Indonesia?

With PT Parva Candela, Instinct Bio has identified two initial cosmetic product candidates for Indonesia under the GENRÊVER and HAKUA brands: a premium UV cream and a moisturizing gel incorporating HA4 low-molecular-weight hyaluronic acid technology. Production is targeted to start within 2026, subject to development, regulatory and manufacturing readiness.

Where can investors find more details on Instinct Bio's GENRÊVER clinic and product plans (BIOT)?

Further information on the GENRÊVER clinic site, subscription structure and the described cosmetic product candidates, as well as the full text of prior related announcements, is available in the News & IR section of Instinct Bio’s website at https://instinct-biot.com/news.