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Bristol-Myers Squibb Company (BMY) is a global biopharmaceutical leader developing innovative therapies in oncology, cardiovascular diseases, and immunology. This dedicated news hub provides investors and healthcare professionals with direct access to BMY's latest developments, including FDA approvals, clinical trial results, and strategic partnerships.
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insitro has received $25 million from Bristol Myers Squibb (BMY) for achieving discovery milestones and selecting the first novel target for amyotrophic lateral sclerosis (ALS) treatment. The milestone stems from their 2020 collaboration agreement. Using their proprietary machine learning platform, insitro developed over 200 engineered and patient ALS cell lines, along with high-content imaging and pooled optical screening technology to identify disease mechanisms and genetic modifiers. The platform successfully identified several novel gene targets that showed promise in reversing ALS-related deficits. Under the agreement terms, insitro received a $50 million upfront payment and could earn up to $2 billion in additional milestones plus royalties.
Bristol Myers Squibb (NYSE: BMY) has announced a quarterly dividend increase of 3.3%, raising it to $0.62 per share from the previous $0.60. The dividend will be paid on February 3, 2025, to stockholders of record as of January 3, 2025. At this rate, the annual dividend for fiscal year 2025 will be $2.48 per share. This marks BMY's 16th consecutive year of dividend increases and 93rd consecutive year of dividend payments. Additionally, the company declared a quarterly dividend of $0.50 per share on its $2.00 convertible preferred stock, payable March 3, 2025, to stockholders of record as of February 4, 2025.
Bristol Myers Squibb (BMY) presented results from 18 studies at ASH 2024, showcasing progress in cell therapy across blood cancers and autoimmune diseases. Key highlights include long-term survival data for Breyanzi in lymphoma treatments, showing 38% 5-year overall survival rate and favorable safety profiles.
The company revealed first survival data for arlocabtagene autoleucel in multiple myeloma, demonstrating 87% overall response rate. New analysis showed 96.8% manufacturing success rate for Abecma globally. Additionally, updated results for CD19 NEX-T showed promise in treating severe autoimmune conditions, including lupus.
AI Proteins and Bristol Myers Squibb (NYSE: BMY) have entered a Research Collaboration and Option Agreement to develop novel miniprotein-based therapeutics. AI Proteins will receive an upfront payment to discover and optimize miniproteins for two undisclosed targets. BMY has options for exclusive worldwide licensing and two additional targets, with potential milestone payments up to $400M plus royalties. The collaboration leverages AI Proteins' AI-driven platform to design small, high-affinity proteins that offer advantages over traditional antibody therapies, including better tissue penetration and rapid clearance.
Bristol Myers Squibb (NYSE: BMY) has announced its participation in Citi's 2024 Global Healthcare Conference. The company's board chair and CEO, Christopher Boerner, Ph.D., will engage in a fireside chat on December 3, 2024, starting at 8:00 a.m. ET. The session will be accessible to investors and the public through a live webcast at http://investor.bms.com, with an archived version available after the event.
Bristol Myers Squibb (NYSE: BMY) announced the presentation of over 90 data disclosures at the 66th ASH Annual Meeting, including 18 oral presentations from its hematology and cell therapy research programs. Key highlights include five-year follow-up data for Breyanzi in large B-cell lymphoma, new analyses from the COMMANDS trial for Reblozyl in myelodysplastic syndromes, and updates on cell therapy platforms including GPRC5D-directed CAR T cell therapy in multiple myeloma. The presentations showcase BMS's diverse portfolio across multiple blood diseases and innovative treatment approaches in targeted protein degradation and cell therapy.
Bristol Myers Squibb (BMY) received a positive CHMP opinion recommending approval of Opdivo plus Yervoy for first-line treatment of adult patients with MSI-H or dMMR metastatic colorectal cancer. The recommendation is based on the Phase 3 CheckMate -8HW trial results, which showed a 79% reduction in risk of disease progression or death compared to chemotherapy (HR: 0.21; p<0.0001). This dual immunotherapy combination would be the first of its kind for first-line metastatic colorectal cancer treatment in the EU. The treatment targets approximately 5-7% of metastatic colorectal cancer patients with dMMR or MSI-H tumors.
Bristol Myers Squibb (BMY) has received a positive recommendation from the European Medicines Agency's CHMP for repotrectinib, a next-generation tyrosine kinase inhibitor. The drug is intended for treating adult patients with ROS1-positive advanced non-small cell lung cancer and patients 12 years and older with advanced NTRK-positive solid tumors. The recommendation is based on the TRIDENT-1 and CARE trials, which showed significant response rates and durable activity. The European Commission's final decision is expected in January 2025.
Bristol Myers Squibb (NYSE: BMY) has announced its participation in two major investor conferences in November 2024. At Guggenheim's Inaugural Healthcare Innovation Conference on November 11, Dr. Samit Hirawat (EVP, Chief Medical Officer) and Dr. Robert Plenge (EVP, Chief Research Officer) will participate in a fireside chat at 10:00 a.m. ET. Later, at the 2024 Jefferies London Healthcare Conference on November 19, David Elkins (EVP, CFO) will join a fireside chat at 9:30 a.m. GMT. Both sessions will be accessible to investors and the public through the company's investor website, with archived recordings available afterward.
Bristol Myers Squibb (NYSE: BMY) presented new long-term data from the Phase 3 EMERGENT-4 and EMERGENT-5 trials evaluating COBENFY in adults with schizophrenia over 52 weeks. The trials demonstrated continued improvement in schizophrenia symptoms and maintenance of effect. EMERGENT-4 showed 69% of participants achieved ≥30% symptom improvement, while EMERGENT-5 showed 30% of participants had ≥30% reduction in PANSS total score. COBENFY was generally well-tolerated with no new safety issues, showing weight loss of approximately 2kg across both trials. Qualitative interviews revealed that 86% of participants reported Quality of Life improvements within six weeks of treatment.