Blueprint Medicines Corp Stock Price, News & Analysis

Blueprint Medicines Corporation (Nasdaq: BPMC) announced that as of February 1, 2023, its Compensation Committee has granted non-qualified stock options for 36,260 shares and restricted stock units (RSUs) for 18,119 shares to 24 new employees under the 2020 Inducement Plan. The options have an exercise price of $46.05, reflecting the stock's closing price on the grant date. Options vest 25% after one year, with additional monthly vesting thereafter, while RSUs follow a similar vesting schedule. The grants are in compliance with Nasdaq Listing Rules.

Blueprint Medicines (NASDAQ: BPMC) will present pivotal results from the PIONEER trial of AYVAKIT® (avapritinib) at the 2023 American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting in San Antonio, from February 24-27. The trial is the largest randomized controlled study in indolent systemic mastocytosis (SM) and highlights AYVAKIT's efficacy across key endpoints. Notably, two oral presentations will occur on February 26, showcasing significant clinical impacts. The FDA is reviewing a supplemental new drug application for AYVAKIT, with a decision expected by May 22, 2023.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced that the FDA has accepted its supplemental new drug application for AYVAKIT® (avapritinib) to treat adults with indolent systemic mastocytosis (SM). The FDA granted priority review and set a PDUFA action date of May 22, 2023. The application is based on the PIONEER trial, the largest randomized study in indolent SM. AYVAKIT notably reduced patient-reported symptoms and demonstrated a well-tolerated safety profile. The company aims to redefine treatment for this rare disease, currently lacking approved therapies for non-advanced SM, thereby potentially transforming patient outcomes.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced the appointment of John Tsai, M.D., to its board of directors. Tsai, with over 20 years in drug development, previously served as President, Global Drug Development, and Chief Medical Officer at Novartis AG. His experience includes the management of 160 projects and 500 clinical trials, leading to approvals of 15 new medicines. The company also announced the retirement of George D. Demetri from the board, who will join the Scientific Advisory Board, having been with Blueprint since December 2014.

Blueprint Medicines Corporation (NASDAQ: BPMC) anticipates achieving the high end of its 2022 revenue guidance, estimating between $180 million and $200 million. The company projects AYVAKIT product revenue between $108 million and $111 million. With potential FDA approval for AYVAKIT in indolent systemic mastocytosis expected mid-2023, the company aims for significant growth. Upcoming clinical catalysts include data releases across various cancer programs, with a focus on expanding treatment options and enhancing patient care.

Blueprint Medicines Corporation (Nasdaq: BPMC) announced the grant of non-qualified stock options for 23,604 shares and 11,800 restricted stock units (RSUs) to 16 new employees, effective December 1, 2022. This grant is part of the 2020 Inducement Plan, aimed at attracting new talent. The options have an exercise price of $47.49 per share, equivalent to the closing price on the grant date. Vesting schedules for the options and RSUs are outlined, requiring continued employment for vesting.

Blueprint Medicines Corporation (NASDAQ: BPMC) has submitted a supplemental new drug application to the FDA for AYVAKIT® (avapritinib) aimed at treating adults with indolent systemic mastocytosis (SM). This submission is based on the registrational PIONEER trial data, the largest of its kind for indolent SM. AYVAKIT has received breakthrough therapy designation from the FDA. The company anticipates presenting detailed PIONEER trial results at the AAAAI Annual Meeting in February 2023. Currently, there are no approved therapies for non-advanced SM.

Blueprint Medicines Corporation (Nasdaq: BPMC), a precision therapy company, announced its participation in two upcoming investor conferences. The Stifel 2022 Healthcare Conference will take place in New York, NY on November 16, 2022 at 2:25 p.m. ET. Additionally, the JMP Securities Hematology and Oncology Summit will be held virtually on December 7, 2022 at 10:20 a.m. ET. Webcasts of the presentations will be available on the company's website for 30 days after each event.

Blueprint Medicines Corporation (Nasdaq: BPMC) announced the grant of stock options and restricted stock units (RSUs) to fourteen new employees effective November 1, 2022. A total of 15,656 stock options and 7,824 RSUs were awarded under the 2020 Inducement Plan, designed for individuals not previously associated with the company. The stock options have an exercise price of $48.24, equal to the closing stock price on the grant date. Vesting schedules include a 25% vesting after one year, followed by monthly or annual vesting, contingent on continued employment.