Biorestorative Therapies Inc Stock Price, News & Analysis

BioRestorative Therapies (NASDAQ:BRTX), a clinical stage regenerative medicine company, has announced a $2 million share repurchase program effective through June 16, 2026. The company's Board of Directors authorized the buyback program, allowing management to repurchase shares through open market transactions or private negotiations. CEO Lance Alstodt expressed confidence in the company's clinical development pipeline and stated that the current share price does not reflect BioRestorative's intrinsic value. The timing, volume, and value of repurchases will be determined by management based on market conditions and other factors, with flexibility to modify or terminate the program at their discretion.

BioRestorative Therapies (NASDAQ: BRTX) presented promising preliminary data from its Phase 2 clinical trial of BRTX-100, an FDA fast-tracked autologous stem cell therapy for chronic lumbar disc disease (cLDD). The data, presented at ISSCR 2025, showed over 74% of subjects achieved >50% improvement in function and 72% reported >50% pain reduction by week 52. The trial has expanded from 15 to 36 subjects, progressing toward full enrollment of 99 participants. The therapy demonstrated an excellent safety profile with no serious adverse events reported between 26-104 weeks at the target dose. The FDA requires >30% improvement in function (ODI) and pain reduction (VAS) for trial continuation and BLA approval. The results consistently exceeded these thresholds, showing strengthening efficacy markers with each new data analysis.

BioRestorative Therapies (NASDAQ:BRTX) has appointed Sandy Lipkins as a key executive focused on technology commercialization and business development, effective June 9, 2025. Lipkins brings over 30 years of venture capital, finance, and sales experience, with particular expertise in anti-aging and wellness sectors. His responsibilities will include managing strategic alliances and licensing agreements both domestically and internationally. Lipkins has a strong track record in stem cells, regenerative medicine, and tissue banking, along with experience in scaling companies and biologics manufacturing. CEO Lance Alstodt emphasized how Lipkins' expertise aligns with BRTX's mission to advance their clinical pipeline and expand their BioCosmeceuticals platform. The appointment represents a strategic move to accelerate growth and expand market presence in regenerative medicine.

BioRestorative Therapies (NASDAQ: BRTX) announced it will present new preliminary Phase 2 clinical data for BRTX-100, its stem cell therapy for chronic lumbar disc disease, at ISSCR 2025 in Hong Kong. The presentation will reveal blinded safety and efficacy data from 30 patients on June 13, 2025. BRTX-100, the company's lead candidate, is an autologous mesenchymal stem cell therapy targeting areas with limited blood flow. The Phase 2 trial is a randomized, double-blinded, placebo-controlled study across 16 U.S. sites, enrolling 99 patients in a 2:1 ratio of treatment to placebo. CEO Lance Alstodt highlighted strong signals in both safety and functional improvement. The company will release detailed data via press release before market open on June 13th.

BioRestorative Therapies (NASDAQ:BRTX) has reported its Q1 2025 financial results and provided significant clinical updates. The company's BRTX-100 program achieved major milestones, including FDA Fast Track designation for chronic lumbar disc disease (cLDD) treatment and IND clearance for chronic cervical discogenic pain. Preliminary clinical data from the Phase 2 trial showed positive safety profiles and efficacy trends. Financial results showed revenues of $25,000 (down from $35,000 in Q1 2024), with a net loss of $5.3 million ($0.64 per share). The company maintains a strong financial position with $9.1 million in cash and equivalents, with no outstanding debt. In their metabolic program, BioRestorative received a European patent allowance for their ThermoStem® platform and continues discussions regarding potential licensing agreements.

BioRestorative Therapies (NASDAQ:BRTX) has reported encouraging preliminary data from its Phase 2 clinical trial of BRTX-100 for chronic lumbar disc disease (cLDD). The data, presented at the ISCT 2025 Annual Meeting, shows no serious adverse events (SAEs) and no dose-limiting toxicity at 26-104 weeks with 40X106 cells. The trial is demonstrating positive efficacy trends, exceeding the FDA's requirement of >30% improvement in both Oswestry Disability Index (ODI) and Visual Analog Scale (VAS). Notably, the percentage of subjects achieving >50% improvement in both ODI and VAS increased significantly from 0% at week 2 to 70% at week 52, maintaining at 66.66% through week 104, indicating strong and sustained therapeutic effects.

BioRestorative Therapies (NASDAQ:BRTX), a clinical stage regenerative medicine company specializing in stem cell-based therapies, has announced it will release its Q1 2025 financial results on Wednesday, May 14, 2025, after market close.

The company will host a conference call at 4:30 p.m. ET to discuss the financial results and provide a business update. Investors can join via domestic (1-888-506-0062) or international (1-973-528-0011) lines using access code 924151. The call will be broadcast live and archived on the company's website in the Investors section.

BioRestorative Therapies (NASDAQ:BRTX) has announced that its Vice President of Research and Development, Francisco Silva, will present an update on the company's ongoing Phase 2 clinical trial of BRTX-100 for chronic lumbar disc disease (cLDD) at the International Society for Cell & Gene Therapy (ISCT) 2025 Annual Meeting. The presentation, titled "Phase 2 Clinical Safety/Efficacy Data of Intradiscal Injection of Hypoxic Mesenchymal Stem Cells for Lumbar Disc Disease," will take place on Thursday, May 8, from 3:45-4:45 pm CT at the conference in New Orleans, LA.

BioRestorative Therapies (NASDAQ:BRTX), a clinical stage regenerative medicine company specializing in stem cell-based therapies, has announced its CEO Lance Alstodt will participate in the Benzinga All-Access Show on April 15, 2025, at 10:50 a.m. Eastern time.

During the interview, the company plans to discuss their recent achievements in clinical and regulatory milestones, along with highlighting commercial opportunities. The session will be accessible via live webcast and will subsequently be archived in the Investors section of the company's website.