Cabaletta Bio, Inc. Stock Price, News & Analysis

Cabaletta Bio, Inc. reported promising initial safety data from the DesCAARTes™ trial for DSG3-CAART, showing no dose-limiting toxicities (DLTs) or adverse events in the first cohort. The company plans to advance two new programs: PLA2R-CAART for PLA2R-associated membranous nephropathy and MuSK-CAART for myasthenia gravis, with IND submissions anticipated in the latter half of 2021. Financially, Cabaletta reported a cash position of $102 million as of March 31, 2021, enabling operations through Q4 2022, despite rising R&D expenses of $6.6 million, up from $4.6 million in Q1 2020.

Cabaletta Bio (CABA) announced positive acute safety data from the first cohort of its Phase 1 DesCAARTes™ clinical trial for DSG3-CAART, targeting mucosal-dominant pemphigus vulgaris. As of April 30, 2021, no dose limiting toxicities (DLTs) or clinically relevant adverse events were reported among the three patients dosed. The company anticipates initiating the second dose cohort after confirming safety data from the first cohort. Acute safety results for the second and third cohorts are expected in Q3 and Q4 2021. A conference call is scheduled for today at 8:30 a.m. ET to discuss these results.

Cabaletta Bio is a clinical-stage biotechnology firm focused on engineered T cell therapies for patients with B cell-mediated autoimmune diseases. On April 14, 2021, at 3:00 p.m. ET, CEO Steven Nichtberger will participate in a fireside chat at the 20th Annual Needham Healthcare Conference. The live webcast will be accessible on the company’s website and will remain available for replay for 90 days. The lead product candidate, DSG3-CAART, targets mucosal pemphigus vulgaris and has received Fast Track Designation from the FDA.

Cabaletta Bio, Inc. (CABA) reported its financial results for Q4 and FY 2020, highlighting significant milestones in its clinical trials. The company successfully dosed the first patient in a Phase 1 trial for DSG3-CAART, targeting mucosal pemphigus vulgaris, without dose limiting toxicities. Financially, R&D expenses increased to $21.4 million in 2020, up from $11.7 million in 2019. The company ended 2020 with $108.7 million in cash, down from $136.2 million a year earlier, ensuring funding through Q3 2022. Key milestones are anticipated in 2021, including additional trial data and an IND submission for MuSK-CAART.

Cabaletta Bio, Inc. (Nasdaq: CABA), a biotechnology firm specializing in engineered T cell therapies for B cell-mediated autoimmune diseases, will participate in two investor conferences in March 2021. The first is the Cowen & Co. 41st Annual Health Care Conference on March 3, where CEO Steven Nichtberger will engage in a cell therapy panel. The second is the H.C. Wainwright Global Life Sciences Conference on March 9, featuring a pre-recorded fireside chat. The discussion will be available on-demand post-conference on the company’s website for 90 days.

Cabaletta Bio, a clinical-stage biotechnology firm listed on Nasdaq as CABA, announced that its CEO, Steven Nichtberger, will present at the 39th Annual J.P. Morgan Healthcare Conference on January 14, 2021, at 5:20 p.m. ET. A live webcast of the event will be available on the company's website and a recording will be accessible for 90 days post-event. Cabaletta is focused on engineered T cell therapies for B cell-mediated autoimmune diseases with its lead candidate, DSG3-CAART, currently in clinical trials.

Cabaletta Bio, a clinical-stage biotechnology company (Nasdaq: CABA), focuses on engineered T cell therapies for B cell-mediated autoimmune diseases. CEO Steven Nichtberger will present at two investor conferences on January 11, 2021. The presentations will be available via webcast on the company's website, starting at 6:00 a.m. and 7:00 a.m. ET respectively. The company's approach utilizes Chimeric AutoAntibody Receptor T cells, targeting specific autoantibody-producing B cells. Its leading candidate, DSG3-CAART, is in a phase 1 clinical trial for mucosal pemphigus vulgaris, with Fast Track Designation from the FDA.

Cabaletta Bio, Inc. (Nasdaq: CABA) achieved a significant milestone by infusing the first patient with its DSG3-CAART therapy during the DesCAARTes™ Phase 1 clinical trial. This trial aims to treat mucosal-dominant pemphigus vulgaris (mPV) and explores CAAR T cell technology for autoimmune diseases. DSG3-CAART could provide a more targeted and durable treatment option compared to current therapies that often induce broad immunosuppression. The trial will assess safety, tolerability, and early efficacy signs with an expected enrollment of 30 subjects across multiple sites in the U.S.

Cabaletta Bio, focused on engineered T cell therapies for B cell-mediated autoimmune diseases, will participate in two investor conferences in December 2020. Steven Nichtberger, M.D., the CEO, will partake in a pre-recorded chat at the Piper Sandler 32nd Annual Virtual Healthcare Conference on December 2 and a live discussion at the Evercore ISI 3rd Annual Virtual HealthCONx Conference on December 3. The company’s pipeline includes DSG3-CAART, which targets mucosal pemphigus vulgaris and has received FDA Fast Track Designation. Webcast replays will be accessible for 90 days on their website.