Cidara Therapeutics to Present Preclincal Data on Multiple Novel Drug-Fc Conjugate Candidates at American Association dor Cancer Research (AACR) Annual Meeting 2024

Rhea-AI Summary

Cidara Therapeutics, Inc. to present preclinical data on drug-Fc conjugate candidates at AACR Annual Meeting, including CD73/PD-1, CCR5, and CBO421 DFCs.

Abstracts to include preclinical data on several drug-Fc conjugate (DFC) candidates including multispecific CD73/PD-1 DFC, CCR5 targeting DFC and CBO421 (CD73 targeting DFC)

SAN DIEGO, March 06, 2024 (GLOBE NEWSWIRE) -- Cidara Therapeutics, Inc. (Nasdaq: CDTX), a biotechnology company using its proprietary Cloudbreak^® platform to develop drug-Fc conjugate (DFC) immunotherapies designed to save lives and improve the standard of care for patients facing serious diseases, today announced the company will be presenting three abstracts and one late-breaking abstract during the American Association for Cancer Research (AACR) Annual Meeting to be held April 5-10, 2024 at the San Diego Convention Center in San Diego, California.

Presentation details are summarized below:

Abstract Title: Discovery of a multispecific CD73/PD-1 targeting Drug Fc-Conjugate (DFC), which improves tumor reduction compared to PD-1 monotherapy in a humanized mouse model
Presenter: James Levin, Ph.D.
Session Category: Immunology
Session Title: Single Target and Bispecific Antibodies
Date and Time: Monday, April 8, 2024, 1:30-5:00 PM PT
Poster Board Number: 19, Section 6

Abstract Title: CBO421: A novel drug Fc-conjugate to prevent tumor immune evasion via the CD73/adenosine pathway
Presenters: Amanda Almaguer and Doug Zuill
Session Category: Immunology
Session Title: Immune Checkpoints and Inhibitory Molecules 2
Date and Time: Monday, April 8, 2024, 1:30-5:00 PM PT
Poster Board Number: 22, Section 4

Abstract Title: CCR5-001, a novel Drug Fc-Conjugate (DFC) targeting CCR5, demonstrates potent efficacy in a colorectal cancer mouse model
Presenter: Simon Döhrmann, Ph.D.
Session Category: Immunology
Session Title: Single Target and Bispecific Antibodies
Date and Time: Monday, April 8, 2024, 1:30-5:00 PM PT
Poster Board Number: 22, Section 6

Abstract Title: CBO421, a novel drug Fc-conjugate, inhibits the enzymatic activity of CD73 and triggers CD73 internalization
Presenters: Elizabeth Abelovski and Nicholas Dedeic, Ph.D.
Session Title: Late-Breaking Research: Immunology 2
Date and Time: Monday, April 8, 2024, 9:00 AM-12:30 PM PT
Poster Board Number: 19, Section 52

About Cidara Therapeutics
Cidara Therapeutics is using its proprietary Cloudbreak^® platform to develop novel drug-Fc conjugates (DFCs). These targeted immunotherapies offer the unique opportunity to create “single molecule cocktails” comprised of targeted small molecules and peptides coupled to a human antibody fragment (Fc). DFCs are designed to save lives and improve the standard of care for patients facing cancers and other serious diseases by inhibiting specific disease targets while simultaneously engaging the immune system. In addition, Cidara received FDA and EU approval for REZZAYO™ (rezafungin for injection), which it has licensed to multiple partners to commercialize in the U.S. and ex-U.S. Cidara is headquartered in San Diego, California. For more information, please visit www.cidara.com.

INVESTOR CONTACT:
Brian Ritchie
LifeSci Advisors
(212) 915-2578
britchie@lifesciadvisors.com

MEDIA CONTACT:
Veronica Eames
LifeSci Communications
(646) 970-4682
veames@lifescicomms.com

What is the focus of the abstracts to be presented by Cidara Therapeutics, Inc. at the AACR Annual Meeting?

The focus is on preclinical data of drug-Fc conjugate candidates, including CD73/PD-1, CCR5, and CBO421 DFCs.

When and where will the American Association for Cancer Research (AACR) Annual Meeting be held?

The AACR Annual Meeting will be held on April 5-10, 2024, at the San Diego Convention Center in San Diego, California.

Who are the presenters of the abstracts on drug-Fc conjugate candidates at the AACR Annual Meeting?

Presenters include James Levin, Amanda Almaguer, Doug Zuill, Simon Döhrmann, Elizabeth Abelovski, and Nicholas Dedeic, Ph.D.

What is the significance of the drug-Fc conjugate CBO421 presented by Cidara Therapeutics, Inc.?

CBO421 is a novel DFC designed to prevent tumor immune evasion via the CD73/adenosine pathway.

Which session category will feature the presentation on CBO421 by Cidara Therapeutics, Inc. at the AACR Annual Meeting?

The presentation on CBO421 will be part of the Immunology Session under the title Immune Checkpoints and Inhibitory Molecules 2.