Welcome to our dedicated page for Celldex Therapeutics news (Ticker: CLDX), a resource for investors and traders seeking the latest updates and insights on Celldex Therapeutics stock.
Celldex Therapeutics, Inc. reports developments as a clinical-stage biotechnology company focused on mast cell biology and antibody-based therapeutics for allergic, inflammatory, autoimmune and other mast cell-mediated diseases. Company updates center on barzolvolimab, a humanized monoclonal antibody being studied across chronic spontaneous urticaria, cold urticaria and symptomatic dermographism, as well as pipeline work that includes CDX-622 in asthma.
Recurring news themes include clinical data presentations at allergy and dermatology meetings, financial results, corporate updates and capital actions. Celldex also reports financing activity tied to its common stock and development priorities for its antibody-based immunology pipeline.
Celldex Therapeutics (Nasdaq: CLDX) has priced its underwritten public offering of 13,377,926 shares at $9.75 each, aiming to raise about $130.4 million. The offering includes a 30-day option for the underwriter to purchase an additional 2,006,688 shares. Proceeds will support ongoing clinical and preclinical development of product candidates and general corporate purposes. The offering is set to close on June 18, 2020, subject to customary conditions. The offering follows a prospectus supplement filed with the SEC on June 12, 2020.
Celldex Therapeutics (Nasdaq: CLDX) announced a proposed underwritten public offering of its common stock, with plans to grant underwriters a 30-day option to purchase an additional 15% of the shares. The company aims to utilize the proceeds for clinical and preclinical development of its product candidates and general corporate purposes. The final terms will depend on market conditions, and there is no guarantee regarding the completion or terms of the offering. Cantor Fitzgerald & Co. is the sole book-running manager for the offering.
Celldex Therapeutics (NASDAQ: CLDX) announced positive results from a Phase 1 study of its KIT inhibitor, CDX-0159, targeting mast cell-driven diseases. Presented at the EAACI Annual Congress 2020, the study showed CDX-0159 induced significant and long-lasting reductions in plasma tryptase levels, indicating effective mast cell suppression. The favorable safety profile and promising data support further development in chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CINDU). Future studies are expected to start later this year, enhancing treatment options for patients.
Celldex Therapeutics (NASDAQ:CLDX) reported significant progress in its pipeline during Q1 2020, despite COVID-19 challenges. The company completed enrollment in the Phase 1 study of its KIT inhibitor, CDX-0159, set for presentation at the EAACI Annual Congress 2020. Celldex plans to expand CDX-0159's development for chronic urticaria and is preparing for a Phase 1 study of CDX-527 in advanced cancers. Q1 2020 financials showed revenues of $2.7 million, primarily from a $1.8 million milestone payment, while net loss decreased to $12.6 million. Celldex's cash is sufficient to fund operations into Q2 2021.
Celldex Therapeutics (NASDAQ: CLDX) announced that results from the Phase 1 study of CDX-0159 will be presented as a late-breaking poster at the EAACI Annual Congress 2020, taking place digitally from June 6-8, 2020. The study shows that CDX-0159, an anti-KIT monoclonal antibody, achieves dose-dependent reductions in serum tryptase levels, indicating a favorable safety profile. Following promising results, Celldex plans to expand CDX-0159's development into Phase 1b studies for chronic spontaneous and inducible urticaria.