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Chemomab Therapeutics Announces Second Quarter 2025 Financial Results and Provides Corporate Update

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Chemomab Therapeutics (Nasdaq: CMMB) reported Q2 2025 financial results and provided updates on its lead drug candidate nebokitug for Primary Sclerosing Cholangitis (PSC). The company is preparing for Phase 3 trials while pursuing strategic partnerships to optimize development resources. Key financial metrics include cash position of $9.5 million as of June 30, 2025, with runway through Q2 2026.

Notable developments include FDA alignment on CMC standards and toxicology testing requirements, new patent issuances in China and Russia, and multiple presentations of Phase 2 SPRING trial data at major scientific meetings. The company also announced plans to implement an ADS ratio change from 1:20 to 1:80 effective August 26, 2025, essentially functioning as a 1:4 reverse split for ADS holders.

Chemomab Therapeutics (Nasdaq: CMMB) ha comunicato i risultati finanziari del secondo trimestre 2025 e ha fornito aggiornamenti sul suo candidato farmaco principale, nebokitug, per la colangite sclerosante primitiva (PSC). L'azienda si sta preparando per gli studi di Fase 3 e sta cercando partnership strategiche per ottimizzare le risorse di sviluppo. Indicatori finanziari chiave includono una liquidità di 9,5 milioni di dollari al 30 giugno 2025, con cassa sufficiente fino al secondo trimestre 2026.

Sviluppi rilevanti: allineamento con la FDA sui requisiti CMC e sui test tossicologici, nuove concessioni di brevetti in Cina e Russia e presentazioni multiple dei dati dello studio di Fase 2 SPRING a importanti congressi scientifici. L'azienda ha inoltre annunciato l'intenzione di modificare il rapporto ADS da 1:20 a 1:80, a partire dal 26 agosto 2025, operazione che equivale a un raggruppamento (reverse split) 1:4 per gli azionisti ADS.

Chemomab Therapeutics (Nasdaq: CMMB) anunció resultados financieros del segundo trimestre de 2025 y actualizaciones sobre su candidato farmacológico principal, nebokitug, para la colangitis esclerosante primaria (PSC). La compañía se prepara para ensayos de Fase 3 y busca alianzas estratégicas para optimizar los recursos de desarrollo. Entre los indicadores financieros clave figura una posición de efectivo de 9,5 millones de dólares al 30 de junio de 2025, con caja hasta el segundo trimestre de 2026.

Hechos relevantes: alineamiento con la FDA sobre normas CMC y requisitos de pruebas toxicológicas, nuevas concesiones de patentes en China y Rusia, y múltiples presentaciones de los datos del ensayo de Fase 2 SPRING en congresos científicos de primer nivel. La compañía también anunció un cambio en la ratio de ADS de 1:20 a 1:80, con efecto desde el 26 de agosto de 2025, que equivale a un reverse split de 1:4 para los tenedores de ADS.

Chemomab Therapeutics (Nasdaq: CMMB)는 2025년 2분기 재무실적을 발표하고 1차 담도경화증(PSC) 치료 후보약물 네보키투그(nebokitug)에 대한 업데이트를 제공했습니다. 회사는 3상 시험 준비를 진행 중이며 개발 자원을 최적화하기 위해 전략적 파트너십을 모색하고 있습니다. 주요 재무 지표로는 2025년 6월 30일 기준 현금 잔액 950만 달러로, 2026년 2분기까지 운영 자금이 확보되어 있습니다.

주요 개발 사항으로는 CMC 기준 및 독성시험 요구사항에 대한 FDA와의 정렬, 중국 및 러시아에서의 신규 특허 등록, 그리고 주요 학회에서의 2상 SPRING 시험 데이터 다수 발표가 포함됩니다. 또한 회사는 2025년 8월 26일부로 ADS 비율을 1:20에서 1:80으로 변경할 예정이라고 발표했으며, 이는 ADS 보유자에게 사실상 1:4 액면병합(reverse split)과 동일합니다.

Chemomab Therapeutics (Nasdaq: CMMB) a publié ses résultats financiers du deuxième trimestre 2025 et a fait le point sur son candidat‑médicament principal, le nebokitug, destiné à la cholangite sclérosante primitive (PSC). La société se prépare aux essais de phase 3 tout en recherchant des partenariats stratégiques pour optimiser les ressources de développement. Parmi les indicateurs financiers clés figurent une trésorerie de 9,5 millions de dollars au 30 juin 2025, assurant une visibilité jusqu'au deuxième trimestre 2026.

Parmi les développements notables : alignement avec la FDA sur les critères CMC et les exigences en matière de tests toxicologiques, délivrances de nouveaux brevets en Chine et en Russie, et multiples présentations des données de l'essai de phase 2 SPRING lors de grandes réunions scientifiques. La société a également annoncé la mise en place d'un changement du ratio ADS de 1:20 à 1:80 effectif au 26 août 2025, correspondant en pratique à un regroupement (reverse split) 1:4 pour les détenteurs d'ADS.

Chemomab Therapeutics (Nasdaq: CMMB) meldete die Finanzergebnisse für Q2 2025 und gab Updates zu seinem führenden Wirkstoffkandidaten Nebokitug für die primär sklerosierende Cholangitis (PSC). Das Unternehmen bereitet Phase‑3‑Studien vor und sucht strategische Partnerschaften, um Entwicklungsressourcen zu optimieren. Wichtige Finanzkennzahlen: Cash‑Position von 9,5 Mio. USD zum 30. Juni 2025, mit Liquidität bis ins zweite Quartal 2026.

Bedeutsame Entwicklungen umfassen die Abstimmung mit der FDA zu CMC‑Standards und toxikologischen Testanforderungen, neue Patenterteilungen in China und Russland sowie mehrere Präsentationen der Phase‑2‑SPRING‑Daten auf bedeutenden wissenschaftlichen Tagungen. Das Unternehmen kündigte außerdem an, das ADS‑Verhältnis von 1:20 auf 1:80 zum 26. August 2025 zu ändern, was für ADS‑Inhaber effektiv einem 1:4 Reverse‑Split entspricht.

Positive
  • FDA agreement on CMC strategy and toxicology testing timeline supports timely program advancement
  • New patent protection secured in China and Russia extending through 2041
  • Phase 2 SPRING trial data received recognition at major scientific meetings
  • Cash runway extended through Q2 2026
  • R&D expenses decreased to $1.3M from $2.9M year-over-year
Negative
  • Net loss of $2.1M in Q2 2025
  • Cash position decreased to $9.5M from $10.6M quarter-over-quarter
  • Dilution from ATM equity offering of 1,023,104 ADSs
  • Phase 3 program dependent on securing strategic partnership

Insights

Chemomab advancing nebokitug for PSC with FDA alignment, seeking strategic partner for Phase 3 while maintaining runway until Q2 2026.

Chemomab continues to methodically build the foundation for its nebokitug Phase 3 program in Primary Sclerosing Cholangitis (PSC), a rare liver disease with no approved disease-modifying therapies. The company has achieved several critical regulatory milestones that strengthen its development pathway. First, they've submitted the Phase 3 protocol to the FDA and are engaging with the European Medicines Agency to enable a global trial. Second, they've secured FDA alignment on both CMC (Chemistry, Manufacturing, and Controls) requirements and the timing of non-clinical toxicology testing, with the FDA allowing toxicology testing to run concurrent with Phase 3 rather than beforehand – a significant timeline advantage.

The scientific profile of nebokitug continues to gain recognition, with Phase 2 SPRING trial data presented at multiple prestigious scientific conferences (EASL, DDW, BSG) and even winning a best presentation award. Proteomic analyses show nebokitug's mechanism – neutralizing CCL24 – impacts multiple disease pathways with anti-fibrotic, anti-inflammatory, and anti-cholestatic effects. These presentations help build awareness among key opinion leaders who will be essential for both clinical trial recruitment and eventual commercialization.

Most significantly, management is pursuing a strategic partnership to advance the Phase 3 program, which appears to be a key gating factor before Phase 3 initiation. While the company has the cash runway until Q2 2026 ($9.5 million as of June 30), the burn rate of $2.3 million per quarter suggests they would need substantial additional capital to independently conduct a Phase 3 trial. The planned reverse split (via ADS ratio change from 1:20 to 1:80) likely aims to maintain Nasdaq compliance while providing flexibility for future financing if needed.

Chemomab's Q2 financial position shows both prudent cash management and the challenges facing small biotech companies advancing to Phase 3 trials. With $9.5 million cash on hand (down from $10.6 million in Q1), the company has a runway through Q2 2026 at current burn rates. Q2 saw reduced R&D expenses of $1.3 million (vs $2.9 million in Q2 2024) due to the completion of the Phase 2 SPRING trial, while G&A remained relatively stable at $1.0 million.

The company's capital strategy appears two-pronged: seeking a strategic partner for Phase 3 development while maintaining ATM (at-the-market) offering capacity as a supplemental funding source. In H1 2025, they raised $1.3 million through the ATM by issuing approximately 1 million ADSs, demonstrating access to capital markets but at a measured pace that suggests they're prioritizing partnership discussions.

The announced ADS ratio change from 1:20 to 1:80 ordinary shares effectively functions as a 1:4 reverse split for ADS holders. This financial engineering doesn't change fundamentals but likely aims to maintain Nasdaq listing compliance by boosting the ADS price above minimum requirements. For investors, this signals that the company recognizes the need to maintain its listing while pursuing its partnership strategy.

The financial runway provides Chemomab negotiating leverage with potential partners, as they're not in an immediate cash crisis. However, the Phase 3 trial would require substantial additional resources beyond current reserves, making the successful execution of a partnership deal the most critical near-term financial catalyst. Management's reference to "near-term value-creating initiatives" suggests they may have additional strategic options beyond traditional partnerships if those discussions don't advance quickly enough.

Phase 3 Preparations Ongoing as Company Continues to Advance Multiple Partnering Options for Executing the Nebokitug Phase 3 Program—

—Phase 2 SPRING Trial Data Highlighting Nebokitug’s Unique Anti-Fibrotic, Anti-Inflammatory and Anti-Cholestatic Effects in PSC Featured at Multiple Major Scientific Meetings—

—FDA and Chemomab Align on CMC and Non-Clinical Toxicology Regulatory Path Forward for Nebokitug—`

—Cash Runway through End of Second Quarter of 2026—

—Announces Plans to Implement ADS Ratio Change Adjustment—

TEL AVIV, Israel, Aug. 14, 2025 (GLOBE NEWSWIRE) -- Chemomab Therapeutics Ltd. (Nasdaq: CMMB), (Chemomab), a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need, today announced financial and operating results for the second quarter ended June 30, 2025, and provided a corporate update.

“In the second quarter of 2025 Chemomab continued to lay the groundwork for the nebokitug Phase 3 program in primary sclerosing cholangitis (PSC) and to progress discussions with potential strategic collaborators. Our goal is to secure the right partner to optimize development resources, accelerate the Phase 3 launch and maximize the commercial potential of nebokitug as the first approved disease-modifying therapy for this devastating disease with enormous unmet medical need,” said Adi Mor, PhD, co-founder, Chief Executive Officer and Chief Scientific Officer of Chemomab. “During the quarter, we submitted our nebokitug Phase 3 protocol to the FDA and look forward to receiving their response soon. We are also engaging in a similar process with the European Medicines Agency, as we plan for a global Phase 3 trial that will include many sites in the E.U. and anticipate that the Phase 3 protocol agreed with the FDA would also support regulatory approvals in Europe. During the quarter we also aligned with the FDA on two additional requirements for the eventual regulatory approval of nebokitugthe CMC standards needed for manufacturing of drug supply for the “to be marketed” formulation as well as the timing of required nonclinical toxicology testing. We look forward to continuing to work closely with the FDA as we finalize the details of the Phase 3 development program.”

Dr. Mor added, “As disclosed previously, we are planning to advance the nebokitug PSC Phase 3 program in collaboration with a strategic partner and we continue in active discussions with a variety of potential partners on multiple possible paths forward. A number of developments during the quarter supported these discussions. Enlarging the scope of our patent protections is relevant for partnerships, and we were pleased to report adding to our existing large and comprehensive intellectual property portfolio with new nebokitug patents in China and Russia, two significant territories for future commercialization. We also presented SPRING trial data at a number of high profile scientific meetings, further raising awareness of nebokitug’s demonstrated potential as a groundbreaking treatment for PSC.”

Dr. Mor concluded, “In parallel to the ongoing activities, we are assessing a number of near-term value-creating initiatives with the potential to accelerate the Phase 3 program and strengthen its probability of success. We anticipate sharing more information about these activities in the coming months.”

Separately, Chemomab plans to change the ratio of its American Depositary Shares ("ADSs") to its ordinary shares (the "ADS Ratio"), from the current ADS Ratio of one ADS to 20 ordinary shares to a new ADS Ratio of one ADS to 80 ordinary shares, effective on August 26, 2025. Chemomab will continue to be traded on the Nasdaq Capital Market under the ticker "CMMB," with an updated CUSIP Number of 16385C104. This ratio adjustment will essentially serve as a one-for-four reverse split for ADS holders and requires no action on their part. The Bank of New York Mellon, the depositary bank for Chemomab’s ADS program, will arrange for the exchange on the effective date. There will be no issuance of new ADSs in connection with the adjustment.

Second Quarter 2025 and Recent Highlights:

  • On June 30, 2025, Chemomab reported that results of the Phase 2 SPRING trial assessing nebokitug for the treatment of PSC were presented in an oral session at BSG Live’25, the annual scientific meeting of the British Society for Gastroenterology. The SPRING trial data was presented by Douglas Thorburn, MD, Professor of Hepatology within the Institute for Liver and Digestive Health at UCL and Principal Investigator of the trial. Post-conference, it was announced that Professor Thorburn’s talk on the SPRING trial results was awarded the prize for the Best Oral Presentation in its respective category at BSG LIVE'25.
  • On June 11, 2025, Chemomab obtained confirmation from the FDA on two development milestones for the nebokitug Phase 3 program. These included agreement with the FDA on the Chemistry, Manufacturing, and Controls (CMC) strategy proposed by Chemomab and its contract manufacturing partner and agreement that additional animal toxicology testing routinely required by the FDA may be conducted in parallel with the nebokitug Phase 3 clinical trial and submitted as part of the planned Biologics Licensing Application. This represents a favorable outcome for Chemomab and supports the timely advancement of the program.
  • On June 3, 2025, Chemomab reported that two new patents covering the use of nebokitug for the treatment of liver diseases, including primary sclerosing cholangitis, were issued in China and Russia, providing coverage up to 2041. These new patents further expand the protections provided by nebokitug’s composition of matter and methods and use patents issued in the U.S., Europe, Japan and additional key territories.
  • On May 5, 2025, Chemomab announced that data from the company’s Phase 2 SPRING trial of nebokitug in PSC was presented in an oral Distinguished Abstract Plenary session at Digestive Disease Week® (DDW 2025) in San Diego, California. The DDW 2025 session presented data from the double-blind, placebo-controlled 15-week treatment period and the 48-week open label extension portion of the study.
  • On April 28, 2025, Chemomab reported data from two study abstracts that were presented as posters at EASL 2025, the Annual Congress of the European Association for the Study of the Liver. In one study, proteomic analyses of 3,000 circulating proteins in patient samples from the SPRING trial showed that nebokitug-treated patients exhibited significant and dose-dependent changes in proteins playing a key role in fibrosis, immune cell recruitment and inflammation. These data highlight how nebokitug’s ability to neutralize CCL24 exerts a wide impact, including reductions in a broad array of inflammatory and fibrotic biomarkers in treated patients. The second study analyzed the pharmacodynamics and pharmacokinetics (PK) of nebokitug and CCL24 using data from the SPRING trial. PK analyses indicated effective antibody-target engagement and linear regression analyses found trends between increasing patient exposure to nebokitug and decreasing levels of PSC disease biomarkers.
  • On April 15, 2025, Chemomab announced new executive medical and clinical appointments. David M. Weiner, MD, rejoined Chemomab as Interim Chief Medical Officer, bringing extensive biotechnology and pharmaceutical industry R&D, drug development and strategic experience, and Jack Lawler, who oversaw the conduct of Chemomab’s successful Phase 2 SPRING Trial in PSC, was promoted to the position of Chief Development Officer.

Second Quarter 2025 Financial Highlights

  • Cash Position: Cash, cash equivalents and short-term bank deposits were $ 9.5 million as of June 30, 2025, compared to $10.6 million as of March 31, 2025. This cash is expected to fund the company through the second quarter of 2026. During the first half of 2025, the company issued 1,023,104 ADSs under its at-the-market (ATM) equity offering program, resulting in net proceeds of $1.3 million
  • Research and Development (R&D) Expenses: R&D expenses were $1.3 million for the second quarter of 2025, compared to $2.9 million for the second quarter of 2024. The decrease in R&D expenses in the second quarter of 2025 compared to the second quarter of 2024 primarily resulted from the end of activities related to the Phase 2 SPRING trial.
  • General and Administrative (G&A) Expenses: G&A expenses were approximately $1.0 million for the second quarter of 2025, compared to $0.8 million for the second quarter of 2024. The increase in G&A expenses primarily reflects increases in noncash share-based expenses.
  • Net Loss: Net loss was $2.1 million, or a net loss of less than $0.01 per basic and diluted ordinary share for the second quarter of 2025, compared to $3.6 million, or a net loss of $0.01 per basic and diluted ordinary share for the second quarter of 2024. The weighted average number of ordinary shares outstanding, basic and diluted, was 463,508,519 (equal to approximately 23.2 million ADSs) for the second quarter of 2025.
  • Liquidity and Capital Resources: Chemomab believes its existing liquidity resources as of June 30th, 2025 will enable it to fund its operations through the second quarter of 2026.
  • Number of Issued and Outstanding Shares: As of June 30, 2025, the company had 413,851,140 Ordinary shares issued and outstanding (equal to 20,692,557 ADSs), compared to 377,132,220 Ordinary shares issued and outstanding (equal to 18,856,611 ADSs) as of December 31, 2024.

Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release, including statements regarding our future financial condition, results of operations, business strategy and plans, and objectives of management for future operations, as well as statements regarding industry trends, are forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “estimate,” “intend,” “may,” “plan,” “potentially,” “will” or the negative of these terms or other similar expressions. We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including, among other things: the risk that certain acknowledgements from the End-of-Phase 2 (EOP2) meeting with the FDA in connection with PSC regulatory approval will not materialize into a pathway for regulatory approval; that certain conclusions and assumptions drawn from the EOP2 meeting with the FDA discussed in the press release will prove incorrect and adversely affect the ability for nebokitug to become an FDA fully approved therapy; the risk that the full data set from the nebokitug study or data generated in further clinical trials of nebokitug will not be consistent with the topline results of the nebokitug Phase 2 PSC trial; failure to obtain, or delays in obtaining, regulatory approvals for nebokitug in the U.S., Europe or other territories; failure to successfully commercialize nebokitug, if approved by applicable regulatory authorities, in the U.S., Europe or other territories, or to maintain U.S., European or other territory regulatory approval for nebokitug if approved; uncertainties in the degree of market acceptance of nebokitug by physicians, patients, third-party payors and others in the healthcare community; nebokitug development of unexpected safety or efficacy concerns related to nebokitug; failure to successfully conduct future clinical trials for nebokitug, including due to the Company's potential inability to enroll or retain sufficient patients to conduct and complete the trials or generate data necessary for regulatory approval, among other things; risks that the Company's clinical studies will be delayed or that serious side effects will be identified during drug development; failure of third parties on which the Company is dependent to manufacture sufficient quantities of nebokitug for commercial or clinical needs, to conduct the Company's clinical trials; changes in laws and regulations applicable to the Company's business and failure to comply with such laws and regulations; business or economic disruptions due to catastrophes or other events, including natural disasters or public health crises; and uncertainties with respect to the Company's need and ability to access future capital; and the intensity and duration of the current war in Israel, and its impact on our operations in Israel. These risks are not exhaustive. You should carefully consider the risks and uncertainties described in the “Risk Factors” sections of our 20-F for the year ended December 31, 2024. New risk factors emerge from time to time, and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. You should not rely upon forward-looking statements as predictions of future events. Except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason after the date of this press release. Before you invest, you should read the documents we have filed and will file with the SEC for more complete information about us. You may get these documents for free by visiting EDGAR on the SEC website at www.sec.gov. This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities law of any such state or jurisdiction.

About Chemomab Therapeutics Ltd.
Chemomab is a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need. Based on the unique role of the soluble protein CCL24 in promoting fibrosis and inflammation, Chemomab developed nebokitug (CM-101), a first-in-class dual activity monoclonal antibody that neutralizes CCL24 and has demonstrated disease-modifying potential. In clinical and preclinical studies, nebokitug has been shown to have a favorable safety profile and has been generally well-tolerated, with the potential to treat multiple severe and life-threatening fibro-inflammatory diseases. Chemomab has reported positive results from four clinical trials of nebokitug in patients. Based on positive data from its Phase 2 SPRING trial in primary sclerosing cholangitis (PSC), the company is preparing for potential initiation of a nebokitug PSC Phase 3 trial. The design of Phase 3 calls for a single pivotal trial based on a clinical event primary endpoint that provides a clear and streamlined pathway to potential full regulatory approval. Nebokitug has received FDA and EMA Orphan Drug and FDA Fast Track designations for the treatment of PSC. Chemomab’s nebokitug program for the treatment of systemic sclerosis has an open U.S. IND. For more information, visit: chemomab.com.

Contacts:

Media & Investors:
Chemomab Therapeutics
Barbara Lindheim
Consulting Vice President
Investor & Public Relations,
Strategic Communications
Phone: +1 917-355-9234
barbara.lindheim@chemomab.com

Chemomab Therapeutics Ltd.
and its subsidiaries

Interim Condensed Consolidated Balance Sheets (Unaudited)      
In USD thousands (except for share amounts) June 30,  December 31, 
  2025  2024 
Assets      
       
Current assets      
Cash and cash equivalents 5,448  6,071 
Short term bank deposits 3,917  8,195 
Restricted cash 148  76 
Other receivables and prepaid expenses 1,101  1,698 
       
Total current assets 10,614  16,040 
       
Non-current assets      
Long term prepaid expenses 298  385 
Property and equipment, net 217  250 
Operating lease right-of-use assets -  289 
Total non-current assets 515  924 
       
Total assets 11,129  16,964 
       
Current liabilities      
Trade payables 378  666 
Accrued expenses 666  1,563 
Employee and related expenses 386  874 
Operating lease liabilities -  115 
       
Total current liabilities 1,430  3,218 
       
Non-current liabilities      
Operating lease liabilities - long term -  209 
       
Total non-current liabilities -  209 
       
Commitments and contingent liabilities      
       
Total liabilities 1,430  3,427 
       
Shareholders' equity (*)      
       
       
Ordinary shares no par value - Authorized: 4,650,000,000 shares as of
June 30, 2025, and as of December 31, 2024;
 -  - 
Issued and outstanding: 413,851,140 Ordinary shares as of June 30, 2025 and
377,132,220 as of December 31, 2024;
 -  - 
Additional paid in capital 117,702  116,160 
Accumulated deficit (108,003) (102,623)
       
Total shareholders’ equity 9,699  13,537 
Total liabilities and shareholders’ equity 11,129  16,964 

(*) 1 American Depositary Share (ADS) represents 20 Ordinary Shares

Chemomab Therapeutics Ltd.
and its subsidiaries

Interim Condensed Consolidated Statements of Operations (Unaudited)
In USD thousands (except for share and per share amounts)
  Three months Three months Six months Six months
  Ended Ended Ended Ended
  June 30, June 30, June 30, June 30,
  2025 2024 2025 2024
Operating expenses        
         
Research and development 1,287 2,928 3,780 6,080
         
General and administrative 975 840 1,969 1,736
         
Total operating expenses 2,262 3,768 5,749 7,816
         
Financing income, net 205 137 369 317
         
Loss before taxes 2,057 3,631 5,380 7,499
         
Taxes on Income - - - -
         
Net loss for the period 2,057 3,631 5,380 7,499


Basic and diluted loss per Ordinary Share (*)0.004 0.013 0.012 0.026
Weighted average number of Ordinary Shares outstanding, basic, and diluted (*)463,508,519 286,080,133 459,829,621 285,111,876

(*) 1 American Depositary Share (ADS) represents 20 Ordinary Shares


FAQ

What were Chemomab's (CMMB) key financial results for Q2 2025?

Chemomab reported a net loss of $2.1M, cash position of $9.5M, R&D expenses of $1.3M, and G&A expenses of $1.0M for Q2 2025.

What is the status of Chemomab's nebokitug Phase 3 program for PSC?

Chemomab has submitted the Phase 3 protocol to FDA, aligned on CMC and toxicology requirements, and is actively seeking strategic partners to advance the program.

What is CMMB's planned ADS ratio change and when will it take effect?

Chemomab will change its ADS ratio from 1:20 to 1:80 ordinary shares, effectively a 1:4 reverse split for ADS holders, effective August 26, 2025.

How long will Chemomab's current cash runway last?

The company's current cash position of $9.5M is expected to fund operations through the end of Q2 2026.

What new developments occurred with nebokitug's patent protection?

Chemomab secured new patents in China and Russia for nebokitug's use in liver diseases, including PSC, providing protection through 2041.
Chemomab Therapeutics Ltd

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