Welcome to our dedicated page for Curis news (Ticker: CRIS), a resource for investors and traders seeking the latest updates and insights on Curis stock.
Curis Inc. reports biotechnology developments centered on emavusertib (CA-4948), an orally available small-molecule IRAK4 and FLT3 inhibitor. Company updates focus on oncology programs in lymphoma, chronic lymphocytic leukemia and acute myeloid leukemia, including clinical data presentations, combination approaches with BTK inhibitors, and studies involving venetoclax and azacitidine.
Recurring Curis news also covers quarterly financial and operating results, conference-call updates, capital actions such as private placements, and security-structure matters involving preferred stock and warrants. The company’s public updates combine clinical-program progress with financing, governance and operating disclosures typical of a development-stage biotechnology issuer.
Curis, Inc. (NASDAQ: CRIS) has announced the 2nd Annual VISTA Symposium, scheduled for September 23, 2022, from 9:00 am to 1:00 pm ET, focusing on VISTA in cancer treatment. Hosted by Dr. Randolph Noelle, the symposium will feature discussions on VISTA biology, immune evasion, and therapeutic strategies. CEO James Dentzer emphasized Curis's leading role in VISTA research, highlighting progress with their program CI-8993. The event will bring together global experts to advance understanding and treatment options for cancer patients.
Curis, a biotechnology company focused on cancer therapeutics, announced that CEO James Dentzer will present at the H.C. Wainwright 24th Annual Global Investment Conference on September 14, 2022, at 4:00 p.m. ET in New York, NY. He will also attend the Cantor Oncology and HemOnc Conference on September 28, 2022, at 3:25 p.m. ET. A webcast of the H.C. Wainwright presentation will be available on the Curis website for 90 days post-event. Curis is developing innovative cancer therapies, including emavusertib, currently in clinical trials.
Curis, Inc. (NASDAQ: CRIS) announced the FDA's approval to resume patient enrollment in the monotherapy phase of its TakeAim Leukemia study. Previously, this study faced a partial hold that the FDA imposed in April 2022 due to safety concerns related to rhabdomyolysis. After reviewing additional data, the FDA allowed Curis to enroll at least nine new patients at the 200mg dose level, while the hold remains for the combination and expansion phases. Curis also projects preliminary clinical data availability in 2023 as it works alongside the FDA on clinical plans for emavusertib.
Curis, Inc. (NASDAQ: CRIS) announced the U.S. FDA lifted the partial clinical hold on its TakeAim Lymphoma Phase 1/2 study of emavusertib. Following the FDA's review, Curis is preparing to resume patient enrollment in Q3 2022. The hold was lifted after agreement on the strategy for managing rhabdomyolysis. Curis will provide a preliminary clinical data update in 2023. The TakeAim Lymphoma study explores emavusertib's effectiveness in treating hematologic malignancies, while the TakeAim Leukemia study remains on hold since April 2022.
Curis, Inc. (CRIS) reported promising clinical results for emavusertib and ibrutinib at ASCO 2022, showing tumor reduction in 8 of 9 evaluable patients, highlighting potential in overcoming ibrutinib resistance. The company appointed Diantha Duvall as CFO, bringing extensive industry experience. For Q2 2022, Curis recorded a net loss of $15.9 million ($0.17/share), a rise from a $10.8 million loss in Q2 2021. Revenue remained stable at $2.4 million. With a strong balance sheet of $107.2 million, Curis is funded into 2024. A conference call is scheduled for today to discuss these results.
Curis, Inc. (NASDAQ: CRIS) announced on July 22, 2022, that its Compensation Committee approved an inducement stock option grant for 540,000 shares to a new employee, effective on the employee's hire date of July 26, 2022. The exercise price matches the stock's closing price on that date. The options have a 10-year term and vest over four years. Curis is engaged in developing cancer therapeutics, including collaborations for innovative treatments. Notably, the FDA has placed a partial clinical hold on certain trials due to safety concerns.
Curis, Inc. (NASDAQ: CRIS) will release its Q2 2022 financial results on August 4, 2022, after the close of U.S. markets. A conference call will be held on the same day at 4:30 pm ET to discuss the results. Investors can dial in or access the call on Curis's website. The company focuses on developing innovative cancer therapeutics, with ongoing trials for its drug emavusertib and partnerships with organizations like Aurigene and Genentech. The FDA has placed a partial clinical hold on certain trials but allows current participants to continue treatment.
Curis, Inc. (NASDAQ: CRIS) announced the grant of 873,750 inducement stock options to 16 new employees, effective July 5, 2022. Each option has an exercise price equal to the closing stock price on that date and vests over four years. This move aims to attract talent and is part of their strategy in developing innovative cancer therapeutics, including ongoing clinical trials for the IRAK4 inhibitor, emavusertib. Curis faces a partial clinical hold on its TakeAim trials, impacting new patient enrollment.
Curis, Inc. (NASDAQ: CRIS) presented novel findings at the 2022 European Hematology Association Congress regarding the IRAK4 inhibitor, emavusertib. The data suggest that nuclear localization of IRAK4 in cancer cells, particularly in acute myeloid leukemia (AML), correlates with better treatment responses. Notably, one patient with primary CNS lymphoma achieved a complete response following emavusertib treatment after prior ibrutinib therapy. The company aims to develop a companion diagnostic for identifying patients most likely to benefit from emavusertib, which is currently undergoing trials for various hematologic malignancies.
Curis, Inc. (NASDAQ: CRIS) presented positive clinical data for emavusertib at the 2022 ASCO Annual Meeting. In the TakeAim Lymphoma study, 8 of 9 evaluable patients achieved tumor reduction, including 2 complete and 2 partial responses. Notably, complete response was observed in a patient with prior ibrutinib treatment, suggesting potential for overcoming ibrutinib resistance. In the TakeAim Leukemia trial, emavusertib showed promising single-agent activity in heavily pretreated AML and HR-MDS patients. The trials are currently under partial clinical hold by the FDA.