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Decibel Therapeutics to Present at the American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting

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Decibel Therapeutics (Nasdaq: DBTX) announced its participation in the ASGCT 25th Annual Meeting from May 15-19, 2022. The company will present its lead gene therapy, DB-OTO, aimed at restoring hearing in individuals with an otoferlin gene mutation. Additionally, two poster presentations will cover the AAV.104 and AAV.103 programs, targeting patients with stereocilin gene mutations and GJB2 deficiencies, respectively. Key presentations will be made by Dr. Orion Keifer Jr. on May 19 at 10:45 am ET and poster sessions on May 16 at 5:30 pm ET.

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BOSTON, May 02, 2022 (GLOBE NEWSWIRE) -- Decibel Therapeutics (Nasdaq: DBTX), a clinical-stage biotechnology company dedicated to discovering and developing transformative treatments to restore and improve hearing and balance, announced today that it will present at the American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting, being held virtually and in Washington D.C. May 15-19, 2022.

The Company will present on its lead investigational gene therapy, DB-OTO, being developed to restore hearing to individuals with a mutation in the otoferlin gene. Decibel will also present two posters featuring its AAV.104 program, a gene therapy designed to restore hearing to individuals with a mutation in the stereocilin gene, and its AAV.103 program, a gene therapy designed to restore hearing to individuals with a GJB2 deficiency, the most common cause of congenital hearing loss.

Details for the oral presentation are as follows:

Development of an AAV-Based Gene Therapy for Children with Congenital Hearing Loss Due to Otoferlin Deficiency (DB-OTO)
Oral Abstract Session: Pharmacology/Toxicology Studies or Assay Development II
Presenter: Orion Keifer Jr, M.D., Ph.D., Senior Medical Director, Decibel Therapeutics
Date & Time: Thursday, May 19, 2022 at 10:45 am ET

Details for the poster presentations are as follows:

M-185 | Dual Vector Mediated Gene Therapy for Restoration of STRC-Related Hearing Loss
Poster Session: Ophthalmic and Auditory Diseases
Date & Time: Monday, May 16, 2022 at 5:30 pm ET

M-183 | Identification of GJB2’s Upstream Regulatory Elements Facilitates Design of Safe, Precision AAVs and Recovery of Hearing in a GJB2-Deficient Mouse Model
Poster Session: Ophthalmic and Auditory Diseases
Date & Time: Monday, May 16, 2022 at 5:30 pm ET

About Decibel Therapeutics
Decibel Therapeutics is a clinical-stage biotechnology company dedicated to discovering and developing transformative treatments to restore and improve hearing and balance, one of the largest areas of unmet need in medicine. Decibel has built a proprietary platform that integrates single-cell genomics and bioinformatic analyses, precision gene therapy technologies and expertise in inner ear biology. Decibel is leveraging its platform to advance gene therapies designed to selectively replace genes for the treatment of congenital, monogenic hearing loss and to regenerate inner ear hair cells for the treatment of acquired hearing and balance disorders. Decibel’s pipeline, including its lead gene therapy product candidate, DB-OTO, to treat congenital, monogenic hearing loss, is designed to deliver on our vision of creating a world of connection for people with hearing and balance disorders. For more information about Decibel Therapeutics, please visit www.decibeltx.com or follow us on Twitter.

Investor Contact:
Julie Seidel
Stern IR, Inc.
212-362-1200
Julie.seidel@sternir.com

Media Contact:
Chris Railey
Ten Bridge Communications
617-834-0936
chris@tenbridgecommunications.com


FAQ

What is Decibel Therapeutics presenting at ASGCT 2022?

Decibel Therapeutics will present its gene therapy DB-OTO, which focuses on restoring hearing in individuals with an otoferlin gene mutation, at the ASGCT 2022 meeting.

When is the oral presentation of DB-OTO scheduled?

The oral presentation of DB-OTO is scheduled for May 19, 2022, at 10:45 am ET.

What are the poster presentations by Decibel Therapeutics about?

Decibel Therapeutics will present two posters on May 16, 2022, focusing on AAV.104 for stereocilin mutations and AAV.103 for GJB2 deficiencies.

Where is the ASGCT 2022 Annual Meeting taking place?

The ASGCT 2022 Annual Meeting is being held virtually and in Washington D.C. from May 15-19, 2022.
Decibel Therapeutics, Inc.

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