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Denali Therapeutics Inc. (DNLI) delivers breakthrough therapies targeting neurodegenerative and lysosomal storage diseases through its innovative blood-brain barrier platform. This page serves as the definitive source for DNLI news, offering investors and researchers timely updates on clinical advancements, regulatory milestones, and strategic collaborations.
Access curated press releases and analysis covering DNLI’s clinical trials, including programs for Parkinson’s disease, ALS, and rare genetic disorders. Track progress on the Transport Vehicle (TV) platform’s applications and partnerships shaping the future of CNS drug development.
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Denali Therapeutics Inc. (DNLI) and Biogen Inc. have entered a significant collaboration with Biogen exercising its option to license Denali's Antibody Transport Vehicle (ATV):Amyloid beta program (ATV:Aβ) aimed at Alzheimer’s treatment.
The ATV technology is designed to enhance the delivery of therapeutic antibodies across the blood-brain barrier, potentially improving efficacy against amyloid beta plaque, a key feature of Alzheimer’s disease. Following this agreement, Biogen will manage all development and commercialization efforts related to the program, while Denali will receive an option exercise payment and may earn milestone payments and royalties based on future sales. This collaboration builds on the partnership initiated in 2020.