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Alpha Tau Announces First-Ever Oral Presentation of Alpha DaRT® Pancreatic Cancer Data at Digestive Disease Week (DDW) 2026

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Alpha Tau (Nasdaq: DRTS) announced acceptance of the first-ever oral presentation of Alpha DaRT pancreatic cancer clinical results at Digestive Disease Week (DDW) 2026.

The abstract, “Updated Results of Feasibility, Safety, and Tumor Control in Two First-In-Human Trials of a Novel Alpha-Emitting Radionuclide for Pancreatic Adenocarcinoma,” will be presented May 2, 2026 at 10:30am Central by Dr. Harold Jacob, using combined data from two Hadassah Medical Center protocols. According to the company, these foundational studies informed the IMPACT pilot now enrolling in the U.S. and ongoing planning toward a future pivotal study.

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News Market Reaction – DRTS

+7.94%
3 alerts
+7.94% Session close to close
+3.8% Peak Tracked
$631.03M Market Cap
0.2x Rel. Volume

In the Mar 31 session, DRTS gained 7.94%, reflecting a notable positive market reaction. Argus tracked a peak move of +3.8% during that session. Our momentum scanner triggered 3 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved +7.9% in the session following this news. A strong positive reaction aligns with Alp...
Analysis

The stock moved +7.9% in the session following this news. A strong positive reaction aligns with Alpha Tau’s history of favorable responses to clinical and regulatory milestones, such as the 11.88% move on prior pancreatic data and gains after Japanese approval. Investors have rewarded concrete progress in difficult indications like pancreatic cancer. However, past divergence on a value-focused update suggests sentiment can shift quickly if expectations reset or if enthusiasm over headline events outpaces tangible execution in trials and commercialization.

Key Figures

Clinical trials count: 2 trials Clinical protocols: 2 protocols DDW session date: May 2, 2026 +1 more
4 metrics
Clinical trials count 2 trials Two clinical trials in Jerusalem pancreatic cancer patients
Clinical protocols 2 protocols Two clinical protocols at Hadassah Medical Center, Jerusalem
DDW session date May 2, 2026 Pancreatic Cancer I: Diagnosis and Treatment session at DDW 2026
Presentation time 10:30am (Central) Scheduled time for DDW oral presentation

Historical Context

5 past events · Latest: Mar 16 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 16 Conference appearance Positive +1.4% CFO presentation at Sidoti Virtual Small Cap investor conference.
Mar 09 Earnings results Positive +1.9% Full-year 2025 results with strong cash, Japanese approval and trial progress.
Feb 24 Regulatory approval Positive +1.2% Japanese Shonin marketing approval for Alpha DaRT in head and neck cancer.
Jan 29 Strategic update Positive -4.7% Shareholder letter outlining five U.S. trials and manufacturing, IP progress.
Jan 06 Clinical data update Positive +11.9% Positive PDAC Alpha DaRT data presented at ASCO GI 2026 with strong DCR/ORR.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent company news has generally seen positive price reactions, with four positive alignments and one notable divergence on a strategic update.

Recent Company History

This announcement adds another clinical milestone to Alpha Tau’s recent string of updates. Since January 2026, the company has reported new positive pancreatic cancer data at ASCO GI 2026, outlined five concurrent U.S. trials and manufacturing scale-up, and secured Japanese marketing approval for Alpha DaRT in unresectable head and neck cancer. Full-year 2025 results highlighted cash of $76.9M and a $42.6M net loss alongside broad clinical and regulatory progress. The new DDW oral presentation continues this focus on expanding pancreatic cancer evidence.

Key Terms

alpha-radiation, pancreatic adenocarcinoma, radionuclide, gastroenterology, +2 more
6 terms
alpha-radiation medical
"the developer of the innovative alpha-radiation cancer therapy Alpha DaRT"
Alpha radiation is a type of ionizing radiation made of heavy, positively charged particles (two protons and two neutrons) emitted by certain radioactive materials; it travels only a short distance and can be stopped by paper or skin but is dangerous if ingested or inhaled. Investors should care because alpha-emitting materials influence regulatory oversight, handling and disposal costs, workplace safety liabilities, and the value of medical or energy projects that use or produce radioactive substances — like a heavy but short‑ranged cannonball that creates big local effects where it lands.
pancreatic adenocarcinoma medical
"for Pancreatic Adenocarcinoma,” has been selected for podium presentation"
Pancreatic adenocarcinoma is a type of cancer that starts in the cells of the pancreas, the organ that helps digestion and controls blood sugar. It matters to investors because it is often aggressive and hard to detect early, so progress or setbacks in diagnostics, drugs or clinical trials can strongly affect the value of companies working on treatments—similar to how a breakthrough or failure in fixing a critical bridge can change the fortunes of contractors and insurers.
radionuclide medical
"a Novel Alpha-Emitting Radionuclide for Pancreatic Adenocarcinoma"
A radionuclide is a type of atom that is unstable and emits radiation as it changes into a more stable form, similar to a tiny battery slowly releasing energy. Investors care about radionuclides because they are the active components in many medical tests and cancer treatments and their production, safety rules, transport logistics and supply reliability can materially affect a company’s costs, regulatory risk and revenue prospects, much like fuel availability affects a factory’s output.
gastroenterology medical
"the world’s premier international gastroenterology conference"
Gastroenterology is the medical specialty that diagnoses and treats disorders of the digestive system—think of it as the maintenance and repair work for the body’s plumbing, including the esophagus, stomach, intestines, liver, pancreas and gallbladder. It matters to investors because demand for related drugs, devices and diagnostics is driven by how common and costly these conditions are, how new treatments perform in trials, and how insurers reimburse care, all of which affect company revenues and valuations.
gastroenterologists medical
"designed to be uniquely suited for delivery by gastroenterologists via EUS"
Gastroenterologists are doctors who diagnose and treat diseases of the digestive system, including the stomach, intestines, liver and pancreas. For investors, they matter because they decide which drugs, medical devices and procedures are used for common and chronic conditions—think of them like specialist mechanics for the body whose choices drive sales, adoption and clinical reputation of healthcare products and services.
eus medical
"uniquely suited for delivery by gastroenterologists via EUS, hopefully positioning"
Endoscopic ultrasound (EUS) is a medical procedure that combines a thin camera on a flexible tube with an ultrasound probe to create detailed images of internal organs and nearby structures, and to guide small tissue samples. For investors, EUS matters because its use and adoption affect demand for specific medical devices, influence clinical trial and diagnostic pathways, and can be tied to regulatory approvals or reimbursement decisions that impact a healthcare company’s revenue and growth prospects.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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JERUSALEM, March 31, 2026 (GLOBE NEWSWIRE) -- Alpha Tau Medical Ltd. (Nasdaq: DRTS, DRTSW) (“Alpha Tau”), the developer of the innovative alpha-radiation cancer therapy Alpha DaRT® today announced that an abstract presenting results of two clinical trials in Jerusalem in patients with pancreatic cancer has been accepted for an oral presentation at Digestive Disease Week (DDW) 2026, the world’s premier international gastroenterology conference. This marks the first time that clinical results of Alpha DaRT in pancreatic cancer patients have been selected for presentation at a major gastroenterology conference.

The abstract, entitled “Updated Results of Feasibility, Safety, and Tumor Control in Two First-In-Human Trials of a Novel Alpha-Emitting Radionuclide for Pancreatic Adenocarcinoma,” has been selected for podium presentation in the Pancreatic Cancer I: Diagnosis and Treatment session on Saturday, May 2, 2026 at 10:30am (Central). The presentation will be led by study Principal Investigator Dr. Harold Jacob, Director of Advanced Gastrointestinal Endoscopy at Hadassah University Medical Center, and is based on combined data from two clinical protocols conducted at Hadassah Medical Center in Jerusalem, Israel.

The acceptance of this abstract for an oral presentation at DDW is an important milestone for Alpha Tau” stated Uzi Sofer, CEO of Alpha Tau, “It reflects the growing recognition of the potential of our technology to address this devastating disease. With the vast majority of pancreatic cancer patients deemed inoperable at diagnosis, Alpha DaRT seeks to offer a truly novel approach for both locally advanced and metastatic patients, and we look forward to sharing these data at DDW.

Dr. Harold Jacob, commented, “I am gratified that our work has been selected for an oral presentation at DDW. As the first clinical data of Alpha DaRT in pancreatic cancer to be presented at a major gastroenterology forum, this acceptance highlights the importance and potential of this technology. Alpha DaRT is designed to be uniquely suited for delivery by gastroenterologists via EUS, hopefully positioning our specialty at the forefront of a new era in pancreatic cancer therapy.

Dr. Robert Den, Chief Medical Officer of Alpha Tau, commented, “The selection of this abstract for an oral presentation at DDW is a testament to the scientific rigor and clinical significance of the work conducted at Hadassah, and of course to Alpha Tau’s excellent investigational technology. These foundational studies have been instrumental in informing our clinical development program, including the IMPACT pilot study now actively enrolling in the U.S., as well as our ongoing work toward a future pivotal study. The full data will be presented at DDW in May.

About DDW 2026

Digestive Disease Week (DDW) is the largest international gathering of physicians, researchers, and academics in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery. DDW 2026 will be held May 2–5, 2026.

About Alpha Tau Medical Ltd.

Founded in 2016, Alpha Tau is an Israeli oncology therapeutics company that focuses on research, development, and potential commercialization of the Alpha DaRT for the treatment of solid tumors. The technology was initially developed by Prof. Itzhak Kelson and Prof. Yona Keisari from Tel Aviv University.

About Alpha DaRT®

Alpha DaRT (Diffusing Alpha-emitters Radiation Therapy) is designed to enable highly potent and conformal alpha-irradiation of solid tumors by intratumoral delivery of radium-224 impregnated sources. When the radium decays, its short-lived daughters are released from the sources and disperse while emitting high-energy alpha particles with the goal of destroying the tumor. Since the alpha-emitting atoms diffuse only a short distance, Alpha DaRT aims to mainly affect the tumor, and to spare the healthy tissue around it.

Forward-Looking Statements

This press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. When used herein, words including “anticipate,” “will,” “plan,” “may,” “continue,” and similar expressions are intended to identify forward-looking statements. In addition, any statements or information that refer to the DDW presentation and Alpha DaRT treatment in pancreatic cancer patients, including the potential benefits, are forward-looking. All forward-looking statements are based upon Alpha Tau’s current expectations and various assumptions. Alpha Tau believes there is a reasonable basis for its expectations and beliefs, but they are inherently uncertain. Alpha Tau may not realize its expectations, and its beliefs may not prove correct. Actual results could differ materially from those described or implied by such forward-looking statements as a result of various important factors, including, without limitation: (i) Alpha Tau’s ability to receive regulatory approval for its Alpha DaRT technology or any future products or product candidates; (ii) Alpha Tau’s limited operating history; (iii) Alpha Tau’s incurrence of significant losses to date; (iv) Alpha Tau’s need for additional funding and ability to raise capital when needed; (v) Alpha Tau’s limited experience in medical device discovery and development; (vi) Alpha Tau’s dependence on the success and commercialization of the Alpha DaRT technology; (vii) the failure of preliminary data from Alpha Tau’s clinical studies to predict final study results; (viii) failure of Alpha Tau’s early clinical studies or preclinical studies to predict future clinical studies; (ix) Alpha Tau’s ability to enroll patients in its clinical trials; (x) undesirable side effects caused by Alpha Tau’s Alpha DaRT technology or any future products or product candidates; (xi) Alpha Tau’s exposure to patent infringement lawsuits; (xii) Alpha Tau’s ability to comply with the extensive regulations applicable to it; (xiii) the ability to meet Nasdaq’s listing standards; (xiv) costs related to being a public company; (xv) changes in applicable laws or regulations; and the other important factors discussed under the caption “Risk Factors” in Alpha Tau’s annual report filed on form 20-F with the SEC on March 9, 2026, and other filings that Alpha Tau may make with the United States Securities and Exchange Commission. These and other important factors could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management’s estimates as of the date of this press release. While Alpha Tau may elect to update such forward-looking statements at some point in the future, except as required by law, it disclaims any obligation to do so, even if subsequent events cause its views to change. These forward-looking statements should not be relied upon as representing Alpha Tau’s views as of any date subsequent to the date of this press release.



Investor Relations Contact:
IR@alphatau.com

FAQ

What will Alpha Tau present about Alpha DaRT at DDW 2026 (DRTS)?

Alpha Tau will present updated feasibility, safety, and tumor control data from two first-in-human pancreatic trials. According to the company, the combined Hadassah data were accepted for an oral podium on May 2, 2026, highlighting clinical findings that inform ongoing U.S. development.

When and where is Alpha DaRT pancreatic data being presented at DDW 2026?

The Alpha DaRT pancreatic abstract is scheduled for an oral presentation on May 2, 2026 at 10:30am Central. According to the company, the talk is in the Pancreatic Cancer I session at Digestive Disease Week, led by Dr. Harold Jacob.

Who will lead the Alpha DaRT pancreatic presentation at DDW and what data source is used?

Dr. Harold Jacob will lead the oral presentation using combined data from two clinical protocols at Hadassah Medical Center. According to the company, these are the first Alpha DaRT pancreatic clinical results presented at a major gastroenterology forum.

How does the DDW presentation affect Alpha Tau's clinical program and IMPACT study (DRTS)?

The DDW presentation publicizes foundational clinical data that informed Alpha Tau's further trials, including the IMPACT pilot now enrolling in the U.S. According to the company, the acceptance supports ongoing planning toward a future pivotal study.

Why is presenting Alpha DaRT pancreatic results at DDW 2026 significant for Alpha Tau (DRTS)?

The acceptance marks the first time Alpha DaRT pancreatic clinical results were chosen for a major gastroenterology conference oral session. According to the company, this milestone signals increasing recognition of the technology within the gastroenterology and oncology communities.